(Q37960068)

25 August 2017

title

Role of arginase in asthma: potential clinical applications (English)

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25 August 2017

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Markus Munder

1

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25 August 2017

language of work or name

English

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publication date

1 January 2010

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Expert Review of Clinical Pharmacology

25 August 2017

published in

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25 August 2017

volume

3

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25 August 2017

issue

1

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25 August 2017

page(s)

17-23

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25 August 2017

cites work

Immunobiology of asthma

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Arginine homeostasis in allergic asthma

21 January 2018

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Nitric oxide in health and disease of the respiratory system

21 January 2018

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Use of exhaled nitric oxide measurements to guide treatment in chronic asthma

21 January 2018

1 reference

Alterations of the arginine metabolome in asthma

21 January 2018

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Decreased arginine bioavailability and increased serum arginase activity in asthma

21 January 2018

1 reference

Genetic polymorphisms in arginase I and II and childhood asthma and atopy

21 January 2018

1 reference

ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts

21 January 2018

1 reference

Roles of arginase variants, atopy, and ozone in childhood asthma

21 January 2018

1 reference

Regulation of immune responses by L-arginine metabolism

21 January 2018

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Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity.

21 January 2018

1 reference

The arginine-arginase balance in asthma and lung inflammation

21 January 2018

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Arginase and pulmonary diseases

21 January 2018

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Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness

21 January 2018

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Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation

21 January 2018

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Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma

21 January 2018

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Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages

21 January 2018

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Functional role and species-specific contribution of arginases in pulmonary fibrosis

21 January 2018

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Transiently, paralleled upregulation of arginase and nitric oxide synthase and the effect of both enzymes on the pathology of asthma

21 January 2018

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Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway

21 January 2018

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Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma.

21 January 2018

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Increased arginase activity in cystic fibrosis airways

21 January 2018

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Glucocorticoid inhibition of interleukin-4 (IL-4) and interleukin-13 (IL-13) induced up-regulation of arginase in rat airway fibroblasts

21 January 2018

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Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response

21 January 2018

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Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment

21 January 2018

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Mechanism of interleukin-25 (IL-17E)-induced pulmonary inflammation and airways hyper-reactivity.

21 January 2018

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Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation

21 January 2018

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Suppression of T-cell functions by human granulocyte arginase

21 January 2018

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Regulation of NK cell function by human granulocyte arginase

21 January 2018

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Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages

21 January 2018

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Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice

21 January 2018

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Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma.

21 January 2018

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Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences

21 January 2018

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IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

21 January 2018

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L-arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction

21 January 2018

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Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects.

21 January 2018

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Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma

21 January 2018

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Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ECP.09.53

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25 August 2017

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