(Q37961732)

26 August 2017

Role of H3K4 demethylases in complex neurodevelopmental diseases (English)

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neurodevelopmental disorder

26 August 2017

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Christopher Wynder

1

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PubMed ID

22121901

26 August 2017

Leanne Stalker

series ordinal

2

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PubMed ID

22121901

26 August 2017

Martin L Doughty

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3

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26 August 2017

1 June 2010

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26 August 2017

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26 August 2017

2

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26 August 2017

3

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26 August 2017

407-418

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Epigenetic mechanisms in memory formation.

26 August 2017

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

21 January 2018

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The role of chromatin during transcription

21 January 2018

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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

21 January 2018

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Dissecting the regulatory circuitry of a eukaryotic genome

21 January 2018

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

21 January 2018

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Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

21 January 2018

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The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

21 January 2018

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Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

21 January 2018

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Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells.

21 January 2018

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Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

21 January 2018

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The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

21 January 2018

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MLL associates specifically with a subset of transcriptionally active target genes

21 January 2018

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Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

21 January 2018

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Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression

21 January 2018

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A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes

21 January 2018

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Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer.

21 January 2018

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The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

21 January 2018

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Sex-specific expression of the X-linked histone demethylase gene Jarid1c in brain

21 January 2018

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Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome

21 January 2018

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Histone lysine methylation: a signature for chromatin function

21 January 2018

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The control of histone lysine methylation in epigenetic regulation

21 January 2018

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Chromatin modifications and their function

21 January 2018

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Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

21 January 2018

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Dynamic Regulation of Histone Lysine Methylation by Demethylases

21 January 2018

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Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage.

21 January 2018

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Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing

21 January 2018

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The key to development: interpreting the histone code?

21 January 2018

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Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

21 January 2018

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Active genes are tri-methylated at K4 of histone H3

21 January 2018

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Histones: annotating chromatin

21 January 2018

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Histone H3 lysine 4 di-methylation: a novel mark for transcriptional fidelity?

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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A chromatin landmark and transcription initiation at most promoters in human cells

21 January 2018

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Application of a translational profiling approach for the comparative analysis of CNS cell types

21 January 2018

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A translational profiling approach for the molecular characterization of CNS cell types

21 January 2018

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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

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Opposing LSD1 complexes function in developmental gene activation and repression programmes

21 January 2018

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21 January 2018

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Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia.

21 January 2018

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cDNA array reveals increased expression of glucose-dependent insulinotropic polypeptide following chronic clozapine treatment: role in atypical antipsychotic drug-induced adverse metabolic effects

21 January 2018

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KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

21 January 2018

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Molecular epigenetics of Angelman syndrome

21 January 2018

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JmjC-domain-containing proteins and histone demethylation

21 January 2018

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Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins.

21 January 2018

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Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.

21 January 2018

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Methylation: lost in hydroxylation?

21 January 2018

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Histone demethylation by a family of JmjC domain-containing proteins

21 January 2018

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PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation

21 January 2018

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The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection

21 January 2018

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The retinoblastoma binding protein RBP2 is an H3K4 demethylase

21 January 2018

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ARID proteins come in from the desert

21 January 2018

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It takes a PHD to read the histone code

21 January 2018

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A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer

21 January 2018

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PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?

21 January 2018

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Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases

21 January 2018

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The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation

21 January 2018

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Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9

21 January 2018

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FOXG1 is responsible for the congenital variant of Rett syndrome

21 January 2018

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Novel FOXG1 mutations associated with the congenital variant of Rett syndrome.

21 January 2018

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A 3 Mb deletion in 14q12 causes severe mental retardation, mild facial dysmorphisms and Rett-like features.

21 January 2018

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Haploinsufficiency of novel FOXG1B variants in a patient with severe mental retardation, brain malformations and microcephaly

21 January 2018

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Isolation and characterization of XE169, a novel human gene that escapes X-inactivation.

21 January 2018

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The murine Xe169 gene escapes X-inactivation like its human homologue.

21 January 2018

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Genetic and epigenetic defects in mental retardation.

21 January 2018

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The many faces of REST oversee epigenetic programming of neuronal genes

21 January 2018

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The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.

21 January 2018

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Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation

21 January 2018

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Novel JARID1C/SMCX mutations in patients with X-linked mental retardation

21 January 2018

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A novel mutation in JARID1C gene associated with mental retardation

21 January 2018

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Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein

21 January 2018

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Identification of a mouse male-specific transplantation antigen, H-Y.

21 January 2018

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Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein

21 January 2018

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RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3

21 January 2018

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MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation

21 January 2018

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A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

21 January 2018

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Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus

21 January 2018

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Cerebellar vermis aplasia: patient report and exclusion of the candidate genes EN2 and ZIC1.

21 January 2018

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Epigenetic regulation in human brain-focus on histone lysine methylation

21 January 2018

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A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

21 January 2018

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Functional interplay between histone demethylase and deacetylase enzymes

21 January 2018

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

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DNA methylation and chromatin modification.

21 January 2018

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MeCP2 dysfunction in Rett syndrome and related disorders

21 January 2018

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Mecp2-null mice provide new neuronal targets for Rett syndrome.

21 January 2018

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Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health.

21 January 2018

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Epigenetic programming of phenotypic variations in reproductive strategies in the rat through maternal care.

21 January 2018

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The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes.

21 January 2018

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Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring.

21 January 2018

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Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

21 January 2018

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Epigenetic programming of stress responses through variations in maternal care

21 January 2018

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The social environment and the epigenome

21 January 2018

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Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation.

21 January 2018

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A histone methyltransferase is required for maximal response to female sex hormones

21 January 2018

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Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules

21 January 2018

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Regulation of gene expression in the nervous system

21 January 2018

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Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders.

21 January 2018

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Huntingtin facilitates polycomb repressive complex 2.

21 January 2018

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Histone H3 and H4 modification profiles in a Rett syndrome mouse model.

21 January 2018

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Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

21 January 2018

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Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

21 January 2018

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REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

21 January 2018

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Mapping Early Brain Development in Autism

21 January 2018

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Total brain volume and corpus callosum size in medication-naïve adolescents and young adults with autism spectrum disorder

21 January 2018

1 reference

The amygdala in autism: not adapting to faces?

21 January 2018

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Revisiting the phenotype associated with FOXG1 mutations: two novel cases of congenital Rett variant

21 January 2018

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Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications

21 January 2018

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Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/EPI.10.12

1 reference

26 August 2017

1 reference

PubMed ID

22121901