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T-bet employs diverse regulatory mechanisms to repress transcription.
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Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
T-bet employs diverse regulatory mechanisms to repress transcription
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author
Kenneth J Oestreich
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Amy S Weinmann
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
publication date
29 November 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Trends in Immunology
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
33
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
78-83
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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T-bet in disease.
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The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns
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T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt
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Molecular mechanisms by which T-bet regulates T-helper cell commitment
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6 September 2017
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.
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Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
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Differentiation of effector CD4 T cell populations (*)
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6 September 2017
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
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Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
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Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases
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6 September 2017
CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus
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Bcl6 mediates the development of T follicular helper cells
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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
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6 September 2017
How are T(H)1 and T(H)2 effector cells made?
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6 September 2017
Surviving the crash: transitioning from effector to memory CD8+ T cell
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A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy
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6 September 2017
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6 September 2017
POZ for effect--POZ-ZF transcription factors in cancer and development
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6 September 2017
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
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PubMed Central
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6 September 2017
IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.
1 reference
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PubMed Central
reference URL
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6 September 2017
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
6 September 2017
NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
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6 September 2017
Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
6 September 2017
A novel transcription factor, T-bet, directs Th1 lineage commitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
6 September 2017
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
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6 September 2017
BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
6 September 2017
Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
14 September 2017
Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
14 September 2017
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
28 September 2017
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
23 June 2018
T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
23 June 2018
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
23 June 2018
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
1 September 2018
A mechanism underlying STAT4-mediated up-regulation of IFN-gamma induction inTCR-triggered T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
1 September 2018
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3273642
retrieved
1 September 2018
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22133865
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-gamma promoter
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22133865
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interaction of NF-kappaB and NFAT with the interferon-gamma promoter
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22133865
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22133865
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.IT.2011.10.005
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PMC publication ID
3273642
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed publication ID
22133865
1 reference
stated in
Europe PubMed Central
PMC publication ID
3273642
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22133865%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
51846205
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