(Q37964608)

26 August 2017

Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy (English)

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26 August 2017

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Takami Sato

1

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26 August 2017

Mizue Terai

2

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26 August 2017

Yutaka Tamura

3

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26 August 2017

Vitali Alexeev

4

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26 August 2017

Michael J Mastrangelo

5

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26 August 2017

Senthamil R Selvan

6

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26 August 2017

1 December 2011

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26 August 2017

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26 August 2017

51

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26 August 2017

2-3

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26 August 2017

170-182

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https://scigraph.springernature.com/pub.10.1007/s12026-011-8262-6

26 August 2017

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cites work

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Macrophage activation and polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

The frequency and suppressor function of CD4+CD25highFoxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Macrophages from irradiated tumors express higher levels of iNOS, arginase-I and COX-2, and promote tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Reactive oxygen species as intracellular messengers during cell growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Mapping of the human IL10 gene and further characterization of the 5' flanking sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

The human interleukin-10 receptor gene maps to chromosome 11q23.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

A model of the ternary complex of interleukin-10 with its soluble receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Comparison of interleukin-22 and interleukin-10 soluble receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Phagocytosis, a potential mechanism for myeloid-derived suppressor cell regulation of CD8+ T cell function mediated through programmed cell death-1 and programmed cell death-1 ligand interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Type 1 T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Regulatory T cells and infection: a dangerous necessity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Neutrophil IL-10 suppresses peritoneal inflammatory monocytes during polymicrobial sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Regulatory T cells and immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 therapy--review of a new approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 induces apoptosis in developing mast cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Targeted inhibition of IL-10-secreting CD25- Treg via p38 MAPK suppression in cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

High incidence of interleukin 10 mRNA but not interleukin 2 mRNA detected in human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Prognostic significance of circulating IL-10 and IL-6 serum levels in colon cancer patients undergoing surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

A synthetic peptide homologous to functional domain of human IL-10 down-regulates expression of MHC class I and Transporter associated with Antigen Processing 1/2 in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin 10 decreases MICA expression on melanoma cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

HLA-G and IL-10 expression in human cancer--different stories with the same message

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 and the immune response against cancer: a counterpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Loss of tumorigenicity and increased immunogenicity induced by interleukin-10 gene transfer in B16 melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Interleukin-10 promotes the maintenance of antitumor CD8(+) T-cell effector function in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

IL-10 expression by primary tumor cells correlates with melanoma progression from radial to vertical growth phase and development of metastatic competence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Recruitment of STAT3 for production of IL-10 by colon carcinoma cells induced by macrophage-derived IL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Human interleukin 10 receptor 1/IgG1-Fc fusion proteins: immunoadhesins for human IL-10 with therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Tumor-associated macrophages mediate immunosuppression in the renal cancer microenvironment by activating the 15-lipoxygenase-2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-011-8262-6

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

21 January 2018

1 reference

12 December 2020

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

1 reference

12 December 2020

C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R

1 reference

12 December 2020

Interleukin 6 mediates production of interleukin 10 in metastatic melanoma.

1 reference

12 December 2020

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production

1 reference

12 December 2020

Interleukin 10 production by human melanoma

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12 December 2020

The role of IL-10 in human B cell activation, proliferation, and differentiation

1 reference

12 December 2020

Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay

1 reference

12 December 2020

Renal cell carcinomas produce IL-6, IL-10, IL-11, and TGF-beta 1 in primary cultures and modulate T lymphocyte blast transformation

1 reference

12 December 2020

Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors

1 reference

12 December 2020

Regulatory NK cells suppress antigen-specific T cell responses

1 reference

12 December 2020

Correlation of serum IL-6, IL-8 and IL-10 levels with clinicopathological features and prognosis in patients with diffuse large B-cell lymphoma

1 reference

12 December 2020

Serum levels of interleukin-6 and interleukin-10 in Turkish patients with aggressive non-Hodgkin's lymphoma.

1 reference

12 December 2020

Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice

1 reference

12 December 2020

IL-10 inhibits human T cell proliferation and IL-2 production

1 reference

12 December 2020

IL-10 inhibits cytokine production by activated macrophages

1 reference

12 December 2020

In vivo effects of locally secreted IL-10 on the murine antitumor immune response

1 reference

12 December 2020

Interleukin-10 is a growth factor for human melanoma cells and down-regulates HLA class-I, HLA class-II and ICAM-1 molecules

1 reference

12 December 2020

Human B-cell interleukin-10: B-cell lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitutively secrete large quantities of interleukin-10.

1 reference

12 December 2020

Cytokines and Immune Response in the Tumor Microenvironment.

1 reference

12 December 2020

CD4+ T Cell Clones Producing both Interferon-γ and Interleukin-10 Predominate in Bronchoalveolar Lavages of Active Pulmonary Tuberculosis Patients

1 reference

12 December 2020

Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells

1 reference

12 December 2020

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

1 reference

12 December 2020

Tumor-derived interleukin-10 as a prognostic factor in stage III patients undergoing adjuvant treatment with an autologous melanoma cell vaccine

1 reference

12 December 2020

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

1 reference

12 December 2020

Interleukin-10 is an autocrine growth factor for acquired immunodeficiency syndrome-related B-cell lymphoma

1 reference

12 December 2020

Advanced colorectal cancer is associated with impaired interleukin 12 and enhanced interleukin 10 production

1 reference

12 December 2020

Human non-small cell lung cancer cells express a type 2 cytokine pattern.

1 reference

12 December 2020

IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells

1 reference

12 December 2020

Cytokine profile of natural killer cells in early human pregnancy

1 reference

12 December 2020

Poor clinical outcome of patients with Hodgkin's disease and elevated interleukin-10 serum levels. Clinical significance of interleukin-10 serum levels for Hodgkin's disease

1 reference

12 December 2020

Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes

1 reference

12 December 2020

Loss of tissue expression of interleukin-10 promotes the disease progression of colorectal carcinoma

1 reference

12 December 2020

Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor

1 reference

12 December 2020

Production of interleukin-10 by human bronchogenic carcinoma.

1 reference

12 December 2020

Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma

1 reference

12 December 2020

Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice

1 reference

12 December 2020

IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response

1 reference

12 December 2020

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

1 reference

12 December 2020

10.1007/S12026-011-8262-6

Identifiers

DOI

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26 August 2017

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