(Q37968322)

26 August 2017

title

Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask (English)

1 reference

26 August 2017

1 reference

regenerative medicine

1 reference

Andrew J Want

1

1 reference

26 August 2017

Alvin W Nienow

series ordinal

2

1 reference

26 August 2017

Christopher J Hewitt

series ordinal

3

1 reference

26 August 2017

Karen Coopman

series ordinal

4

1 reference

26 August 2017

publication date

1 January 2012

1 reference

26 August 2017

published in

Regenerative Medicine

1 reference

26 August 2017

volume

7

1 reference

26 August 2017

issue

1

1 reference

26 August 2017

page(s)

71-84

1 reference

Effectiveness of alternative treatments for reducing potential viral contaminants from plasma-derived products

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Automated, scalable culture of human embryonic stem cells in feeder-free conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Automated maintenance of embryonic stem cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Differences between human embryonic stem cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Embryonic stem cell lines derived from human blastocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Common culture conditions for maintenance and cardiomyocyte differentiation of the human embryonic stem cell lines, BG01 and HUES-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Feeder-free growth of undifferentiated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Feeder- and serum-free establishment and expansion of human induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Matrigel: basement membrane matrix with biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Matrigel: a complex protein mixture required for optimal growth of cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Derivation of human embryonic stem cells in defined conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Innovation in the culture and derivation of pluripotent human stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Feeder layer- and serum-free culture of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alphavbeta5 integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Synthetic surfaces for human embryonic stem cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Hydrogels as artificial matrices for human embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Development of Scalable Culture Systems for Human Embryonic Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Derivation and characterisation of the human embryonic stem cell lines, NOTT1 and NOTT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Defined and serum-free media support undifferentiated human embryonic stem cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Toward xeno-free culture of human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Reactor engineering in large scale animal cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Differential protein expression following low temperature culture of suspension CHO-K1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Expansion of mouse embryonic stem cells on microcarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Mouse embryonic stem cell expansion in a microcarrier-based stirred culture system

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Cardiomyocyte production in mass suspension culture: embryonic stem cells as a source for great amounts of functional cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Embryonic stem cells remain highly pluripotent following long term expansion as aggregates in suspension bioreactors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Attachment and growth of human embryonic stem cells on microcarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Three-dimensional culture systems for the expansion of pluripotent embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Long-term microcarrier suspension cultures of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Basic fibroblast growth factor support of human embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Critical microcarrier properties affecting the expansion of undifferentiated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Low O2 tensions and the prevention of differentiation of hES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Adaptation to oxygen deprivation in cultures of human pluripotent stem cells, endothelial progenitor cells, and umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

A reduced oxygen tension (5%) is not beneficial for maintaining human embryonic stem cells in the undifferentiated state with short splitting intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Characterization of hybridoma cell responses to elevated pCO(2) and osmolality: intracellular pH, cell size, apoptosis, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Strategies for improved dCO2 removal in large-scale fed-batch cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Mechanobiology of adult and stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Bioreactor cultivation enhances the efficiency of human embryoid body (hEB) formation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Establishing a dynamic process for the formation, propagation, and differentiation of human embryoid bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Cardiac cell generation from encapsulated embryonic stem cells in static and scalable culture systems

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Long term expansion of undifferentiated human iPS and ES cells in suspension culture using a defined medium

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Scalable stirred-suspension bioreactor culture of human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Immortalized feeders for the scale-up of human embryonic stem cells in feeder and feeder-free conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Evaluation of Chinese hamster ovary cell stability during repeated batch culture for large-scale antibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

CD30 expression reveals that culture adaptation of human embryonic stem cells can occur through differing routes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

The scale-up of microbial batch and fed-batch fermentation processes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Separation of SSEA-4 and TRA-1-60 labelled undifferentiated human embryonic stem cells from a heterogeneous cell population using magnetic-activated cell sorting (MACS) and fluorescence-activated cell sorting (FACS).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Controlled-size embryoid body formation in concave microwell arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Embryonic stem cell bioprinting for uniform and controlled size embryoid body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Teratomas from pluripotent stem cells: A clinical hurdle

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Cardiac cell repair therapy: a clinical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Suspension culture of undifferentiated human embryonic and induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Engineering cell metabolism for high-density cell culture via manipulation of sugar transport

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Conversion of a CHO cell culture process from perfusion to fed-batch technology without altering product quality.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Ranking bioprocess variables using global sensitivity analysis: a case study in centrifugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Quantities of cells used for regenerative medicine and some implications for clinicians and bioprocessors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Scalable culture and cryopreservation of human embryonic stem cells on microcarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

Growth of Cell-strains and Primary Cells on Micro-carriers in Homogeneous Culture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FRME.11.101

21 January 2018

Identifiers

DOI

10.2217/RME.11.101

1 reference

26 August 2017

1 reference