(Q37970398)

26 August 2017

title

Colorectal cancer mouse models: integrating inflammation and the stroma (English)

1 reference

26 August 2017

1 reference

1 reference

Matthias Ernst

1

1 reference

26 August 2017

Robert G Ramsay

series ordinal

2

1 reference

26 August 2017

publication date

1 January 2012

1 reference

Journal of Gastroenterology and Hepatology

26 August 2017

published in

1 reference

26 August 2017

volume

27

1 reference

26 August 2017

issue

1

1 reference

26 August 2017

page(s)

39-50

1 reference

Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Autoimmune disease and subsequent risk of developing alimentary tract cancers among 4.5 million US male veterans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Effect of aspirin and NSAIDs on risk and survival from colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

The role of COX-2 in intestinal inflammation and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Chemoprevention of colorectal cancer: systematic review and economic evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. III. Entero-endocrine cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Stem cells: the intestinal stem cell as a paradigm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Identification of stem cells in small intestine and colon by marker gene Lgr5

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Bmi1 is expressed in vivo in intestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Ligand-independent toll-like receptor signals generated by ectopic overexpression of MyD88 generate local and systemic antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Apc mice: models, modifiers and mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

The roles of sPLA2-IIA (Pla2g2a) in cancer of the small and large intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

c-Myb is required for progenitor cell homeostasis in colonic crypts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Crypt stem cells as the cells-of-origin of intestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Experimental inflammatory bowel disease: insights into the host-microbiota dialog

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Perforin deficiency attenuates inflammation and tumor growth in colitis-associated cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Predominant T helper type 2-inflammatory responses promote murine colon cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Voluntary exercise inhibits intestinal tumorigenesis in Apc(Min/+) mice and azoxymethane/dextran sulfate sodium-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

AOM-induced mouse colon tumors do not express full-length APC protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Inflammation and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

NF-kappaB as a critical link between inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

STATs in cancer inflammation and immunity: a leading role for STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Acquiring signalling specificity from the cytokine receptor gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Stat proteins and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

A role for JAK2 mutations in myeloproliferative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

MYB function in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

c-Myb is critical for murine colon development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Expression of stress response protein glucose regulated protein-78 mediated by c-Myb

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Members of the nuclear factor kappa B family transactivate the murine c-myb gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

cAMP-induced NF-kappaB (p50/relB) binding to a c-myb intronic enhancer correlates with c-myb up-regulation and inhibition of erythroleukemia cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

NF-kappaB signaling pathway, inflammation and colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

Myb controls intestinal stem cell genes and self-renewal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06883.X

10.1111/J.1440-1746.2011.06883.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference