(Q37983138)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Cerebral malaria pathogenesis: revisiting parasite and host contributions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

0 references

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Georges E Grau

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Georges Emile Raymond Grau

series ordinal

1

1 reference

26 August 2017

publication date

1 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

Future Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

291-302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324996%20AND%20SRC:MED&resulttype=core&format=json

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial

22 January 2020

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Pathogenesis, clinical features, and neurological outcome of cerebral malaria

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The spectrum of retinopathy in adults with Plasmodium falciparum malaria

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Redefining cerebral malaria by including malaria retinopathy

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The neuropathology of fatal cerebral malaria in malawian children

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Malaria parasite proteins that remodel the host erythrocyte

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Genetics of antigenic variation in Plasmodium falciparum

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Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

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PfEMP1-DBL1alpha amino acid motifs in severe disease states of Plasmodium falciparum malaria

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Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks

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CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

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Plasmodium falciparum var gene expression is modified by host immunity

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In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children

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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

21 January 2018

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Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies

21 January 2018

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Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria

21 January 2018

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Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome

21 January 2018

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The role of reduced red cell deformability in the pathogenesis of severe falciparum malaria and its restoration by blood transfusion

21 January 2018

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Direct in vivo assessment of microcirculatory dysfunction in severe falciparum malaria

21 January 2018

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Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes

21 January 2018

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Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB.

21 January 2018

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Altered phenotype and gene transcription in endothelial cells, induced by Plasmodium falciparum-infected red blood cells: pathogenic or protective?

21 January 2018

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Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium

21 January 2018

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Plasmodium falciparum and the blood-brain barrier--contacts and consequences.

21 January 2018

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Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers.

21 January 2018

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Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium

21 January 2018

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Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions.

21 January 2018

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Evidence of blood-brain barrier dysfunction in human cerebral malaria

21 January 2018

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Down-regulation of tight junction mRNAs in human endothelial cells co-cultured with Plasmodium falciparum-infected erythrocytes

21 January 2018

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Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum

21 January 2018

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Elevated cell-specific microparticles are a biological marker for cerebral dysfunctions in human severe malaria

21 January 2018

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Circulating red cell-derived microparticles in human malaria

21 January 2018

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Src-family kinase signaling modulates the adhesion of Plasmodium falciparum on human microvascular endothelium under flow

21 January 2018

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Ectophosphorylation of CD36 regulates cytoadherence of Plasmodium falciparum to microvascular endothelium under flow conditions

21 January 2018

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Levamisole inhibits sequestration of infected red blood cells in patients with falciparum malaria

21 January 2018

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Platelets reorient Plasmodium falciparum-infected erythrocyte cytoadhesion to activated endothelial cells

21 January 2018

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Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings

21 January 2018

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Plasmodium falciparum intercellular adhesion molecule-1-based cytoadherence-related signaling in human endothelial cells

21 January 2018

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Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites

21 January 2018

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Plasmodium falciparum glycosylphosphatidylinositol induces limited apoptosis in liver and spleen mouse tissue

21 January 2018

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Glycosylphosphatidylinositol-induced cardiac myocyte death might contribute to the fatal outcome of Plasmodium falciparum malaria

21 January 2018

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Innate inflammatory response to the malarial pigment hemozoin

21 January 2018

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Intraleucocytic malaria pigment and prognosis in severe malaria

21 January 2018

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Intraleucocytic malaria pigment and clinical severity of malaria in children

21 January 2018

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Purified malaria pigment (hemozoin) enhances dendritic cell maturation and modulates the isotype of antibodies induced by a DNA vaccine

21 January 2018

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Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function

21 January 2018

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Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal

21 January 2018

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Host fibrinogen stably bound to hemozoin rapidly activates monocytes via TLR-4 and CD11b/CD18-integrin: a new paradigm of hemozoin action

21 January 2018

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Phagocytosis of hemozoin enhances matrix metalloproteinase-9 activity and TNF-alpha production in human monocytes: role of matrix metalloproteinases in the pathogenesis of falciparum malaria

21 January 2018

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Natural haemozoin modulates matrix metalloproteinases and induces morphological changes in human microvascular endothelium

21 January 2018

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Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study

21 January 2018

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von Willebrand factor propeptide in malaria: evidence of acute endothelial cell activation

21 January 2018

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Thrombocytopenia and release of activated von Willebrand Factor during early Plasmodium falciparum malaria

21 January 2018

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Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition

21 January 2018

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Severe malaria is associated with a deficiency of von Willebrand factor cleaving protease, ADAMTS13.

21 January 2018

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Functional architecture of Weibel-Palade bodies

21 January 2018

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Immune mimicry in malaria: Plasmodium falciparum secretes a functional histamine-releasing factor homolog in vitro and in vivo

21 January 2018

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The physiological approach to the problems of malaria

21 January 2018

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Cerebral malaria -- a neurovascular pathology with many riddles still to be solved.

21 January 2018

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Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria

21 January 2018

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Tumor necrosis factor and disease severity in children with falciparum malaria

21 January 2018

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TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria

21 January 2018

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Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria

21 January 2018

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Neuropathogenesis of human and murine malaria

21 January 2018

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Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes

21 January 2018

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Malignant malaria and microangiopathies: merging mechanisms

21 January 2018

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Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study

21 January 2018

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Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children

21 January 2018

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Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

21 January 2018

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Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor

21 January 2018

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Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria

21 January 2018

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Induction of pro-inflammatory mediators in Plasmodium berghei infected BALB/c mice breaks blood-brain-barrier and leads to cerebral malaria in an IL-12 dependent manner

21 January 2018

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Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

21 January 2018

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Early cytokine production is associated with protection from murine cerebral malaria

21 January 2018

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[Role of histamine and histamine receptors in the pathogenesis of malaria].

21 January 2018

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Histamine H(3) receptor-mediated signaling protects mice from cerebral malaria

21 January 2018

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C5 deficiency and C5a or C5aR blockade protects against cerebral malaria

21 January 2018

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Heme moves to center stage in cerebral malaria

21 January 2018

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A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction.

21 January 2018

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Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria

21 January 2018

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Is there an interaction between human immunodeficiency virus and Plasmodium falciparum?

21 January 2018

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Defining childhood severe falciparum malaria for intervention studies

21 January 2018

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Host immunity as a determinant of treatment outcome in Plasmodium falciparum malaria

21 January 2018

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Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria

21 January 2018

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On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria

21 January 2018

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Murine cerebral malaria: the whole story

21 January 2018

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A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

21 January 2018

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CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis.

21 January 2018

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CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo

21 January 2018

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Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria

21 January 2018

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Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria

21 January 2018

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Retinal pathology of pediatric cerebral malaria in Malawi

21 January 2018

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TNF in vascular pathology: the importance of platelet-endothelium interactions

21 January 2018

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TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria

21 January 2018

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Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria

21 January 2018

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Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis.

21 January 2018

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Differential microRNA expression in experimental cerebral and noncerebral malaria.

21 January 2018

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Human cerebral malaria and the blood-brain barrier

21 January 2018

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Direct cell/cell contact with stimulated T lymphocytes induces the expression of cell adhesion molecules and cytokines by human brain microvascular endothelial cells.

21 January 2018

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Magnetic resonance imaging of the brain in patients with cerebral malaria

21 January 2018

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Isolated cerebellar edema and obstructive hydrocephalus in a child with cerebral malaria

21 January 2018

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Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema.

21 January 2018

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In the eye of experimental cerebral malaria

21 January 2018

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Coma in fatal adult human malaria is not caused by cerebral oedema

21 January 2018

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Brain swelling and mannitol therapy in adult cerebral malaria: a randomized trial

21 January 2018

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Elevated levels of vascular endothelial growth factor (VEGF) and soluble vascular endothelial growth factor receptor (VEGFR)-2 in human malaria

21 January 2018

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Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

21 January 2018

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Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria

21 January 2018

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Recovery of endothelial function in severe falciparum malaria: relationship with improvement in plasma L-arginine and blood lactate concentrations

21 January 2018

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Host response to cytoadherence in Plasmodium falciparum

21 January 2018

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Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF.

21 January 2018

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Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma

21 January 2018

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Cell vesiculation and immunopathology: implications in cerebral malaria

21 January 2018

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Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier

21 January 2018

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https://api.crossref.org/works/10.2217%2FFMB.11.155

Soluble factors from plasmodium falciparum-infected erythrocytes induce apoptosis in human brain vascular endothelial and neuroglia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Glial activation and matrix metalloproteinase release in cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Cellular stress and injury responses in the brains of adult Vietnamese patients with fatal Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Axonal and astrocyte injury markers in the cerebrospinal fluid of Kenyan children with severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Cerebral calpain in fatal falciparum malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Compromised blood-nerve barrier, astrogliosis, and myelin disruption in optic nerves during fatal murine cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Immunopathogenesis of cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Persistent neurocognitive impairments associated with severe falciparum malaria in Kenyan children.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Developmental impairments following severe falciparum malaria in children

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Rehabilitation for cognitive impairments after cerebral malaria in African children: strategies and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Severe neurological sequelae and behaviour problems after cerebral malaria in Ugandan children

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155

Inflammatory changes in the central nervous system are associated with behavioral impairment in Plasmodium berghei (strain ANKA)-infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.11.155