(Q37990051)

26 August 2017

title

Review article: the iron overload syndromes (English)

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26 August 2017

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A Siddique

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26 August 2017

K V Kowdley

series ordinal

2

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26 August 2017

language of work or name

English

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publication date

4 March 2012

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Alimentary Pharmacology & Therapeutics

26 August 2017

published in

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26 August 2017

volume

35

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26 August 2017

issue

8

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26 August 2017

page(s)

876-893

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

26 August 2017

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A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

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The role of transporters in cellular heme and porphyrin homeostasis

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Characterization and partial purification of a ferrireductase from human duodenal microvillus membranes

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The role of Dcytb in iron metabolism: an update

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A novel mammalian iron-regulated protein involved in intracellular iron metabolism

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Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

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Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

21 January 2018

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An update on iron physiology.

21 January 2018

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pH and the recycling of transferrin during receptor-mediated endocytosis

21 January 2018

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A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron

21 January 2018

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The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein

21 January 2018

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Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

21 January 2018

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Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

21 January 2018

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Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

21 January 2018

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Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

21 January 2018

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Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

21 January 2018

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Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

21 January 2018

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Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

21 January 2018

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The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

21 January 2018

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Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract

21 January 2018

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Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse.

21 January 2018

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Mechanisms of iron accumulation in hereditary hemochromatosis

21 January 2018

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Molecular insights into the pathogenesis of hereditary haemochromatosis

21 January 2018

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Physiologic systemic iron metabolism in mice deficient for duodenal Hfe

21 January 2018

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Penetrance of 845G--> A (C282Y) HFE hereditary haemochromatosis mutation in the USA.

21 January 2018

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Iron-overload-related disease in HFE hereditary hemochromatosis

21 January 2018

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Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Transferrin receptor 2 (TfR2) and HFE mutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Early onset hereditary hemochromatosis resulting from a novel TFR2 gene nonsense mutation (R105X) in two siblings of north French descent

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Non-classical hereditary hemochromatosis in Portugal: novel mutations identified in iron metabolism-related genes

21 January 2018

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A novel mutation of transferrin receptor 2 in a Taiwanese woman with type 3 hemochromatosis

21 January 2018

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New mutations inactivating transferrin receptor 2 in hemochromatosis type 3.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

21 January 2018

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Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin 1 gene (SLC11A3)

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Novel mutation in ferroportin1 is associated with autosomal dominant hemochromatosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

21 January 2018

The ferroportin disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Recent advances in understanding haemochromatosis: a transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

A novel missense mutation in SLC40A1 results in resistance to hepcidin and confirms the existence of two ferroportin-associated iron overload diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Iron absorption and loading in beta-thalassaemia intermedia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Ferroportin (Q248H) mutations in African families with dietary iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Upregulation of transferrin receptor 2 and ferroportin 1 mRNA in the liver of patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Iron accumulation in alcoholic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Serum ferritin and transferrin saturation in patients with chronic alcoholic and non-alcoholic liver diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Serum thioredoxin elucidates the significance of serum ferritin as a marker of oxidative stress in chronic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Nonalcoholic fatty liver disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Steatohepatitis: a tale of two "hits"?

21 January 2018

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Iron overload is associated with hepatic oxidative damage to DNA in nonalcoholic steatohepatitis

21 January 2018

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Interaction of iron, insulin resistance, and nonalcoholic steatohepatitis

21 January 2018

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HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis.

21 January 2018

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Clinical characteristics and prevalence of GB virus C, SEN virus, and HFE gene mutation in Japanese patients with nonalcoholic steatohepatitis

21 January 2018

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Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH

21 January 2018

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High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic.

21 January 2018

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The neurological presentation of ceruloplasmin gene mutations

21 January 2018

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Hereditary ceruloplasmin deficiency with hemosiderosis: a clinicopathological study of a Japanese family

21 January 2018

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EASL International Consensus Conference on Haemochromatosis

21 January 2018

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A population-based study of the clinical expression of the hemochromatosis gene

21 January 2018

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Serum Ferritin Level Predicts Advanced Hepatic Fibrosis among U.S. Patients with Phenotypic Hemochromatosis

21 January 2018

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Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis

21 January 2018

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Reversibility of hepatic fibrosis in treated genetic hemochromatosis: a study of 36 cases.

21 January 2018

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Are haemochromatosis mutations related to the severity of liver disease in hepatitis C virus infection?

21 January 2018

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Insulin resistance-associated hepatic iron overload.

21 January 2018

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Declining prevalence of diabetes mellitus in hereditary haemochromatosis--the result of earlier diagnosis

21 January 2018

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Hypogonadotropic hypogonadism in idiopathic hemochromatosis: evidence for combined hypothalamic and pituitary involvement.

21 January 2018

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Hereditary hemochromatosis as a risk factor for joint replacement surgery

21 January 2018

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Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance

21 January 2018

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What's new in hemochromatosis

21 January 2018

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Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives

21 January 2018

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Increased cancer risk in a cohort of 230 patients with hereditary hemochromatosis in comparison to matched control patients with non-iron-related chronic liver disease.

21 January 2018

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HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

21 January 2018

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Iron, hemochromatosis, and hepatocellular carcinoma

21 January 2018

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Biological variability of transferrin saturation and unsaturated iron-binding capacity.

21 January 2018

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Distribution of transferrin saturation in an Australian population: relevance to the early diagnosis of hemochromatosis.

21 January 2018

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Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis.

21 January 2018

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The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis.

21 January 2018

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Review article: haemochromatosis

21 January 2018

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Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases

21 January 2018

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Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Non-invasive evaluation of liver fibrosis using transient elastography

21 January 2018

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Liver fat: effect of hepatic iron deposition on evaluation with opposed-phase MR imaging

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Magnetic resonance imaging measurement of iron overload

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Clinical expression of haemochromatosis in Irish C282Y homozygotes identified through family screening.

21 January 2018

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Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment

21 January 2018

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HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis

21 January 2018

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The arthropathy of hemochromatosis. Recent studies

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

INTERACTION OF VITAMIN C AND IRON

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Therapeutic erythrocytapheresis versus phlebotomy in the initial treatment of hereditary hemochromatosis - A pilot study

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Liver transplantation for hereditary hemochromatosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Survival of liver transplant recipients with hemochromatosis in the United States

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

The effect of iron depletion on chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: evidence from a case-control study.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2036.2012.05051.X

Association between iron overload and osteoporosis in patients with hereditary hemochromatosis

21 January 2018

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21 January 2018

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Hepatocellular carcinoma occurring in nonfibrotic liver: Epidemiologic and histopathologic analysis of 80 French cases

21 January 2018

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Use of community genetic screening to prevent HFE-associated hereditary haemochromatosis

21 January 2018

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10.1111/J.1365-2036.2012.05051.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference