(Q37994716)

26 August 2017

title

Developmental immunotoxicity (DIT) testing of pharmaceuticals: current practices, state of the science, knowledge gaps, and recommendations (English)

1 reference

26 August 2017

main subject

knowledge gap hypothesis

1 reference

1 reference

Mark Collinge

1

1 reference

26 August 2017

Leigh Ann Burns-Naas

2

1 reference

26 August 2017

Gary J Chellman

3

1 reference

26 August 2017

Thomas T Kawabata

4

1 reference

26 August 2017

Wendy J Komocsar

5

1 reference

26 August 2017

Joseph R Piccotti

6

1 reference

26 August 2017

Jacintha Shenton

7

1 reference

26 August 2017

Daniel Wierda

8

1 reference

26 August 2017

publication date

19 March 2012

1 reference

Journal of Immunotoxicology

26 August 2017

published in

1 reference

26 August 2017

volume

9

1 reference

26 August 2017

issue

2

1 reference

26 August 2017

page(s)

210-230

1 reference

Persistence of maternal antibody in infants beyond 12 months: mechanism of measles vaccine failure

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental and peri-postnatal study in cynomolgus monkeys with belimumab, a monoclonal antibody directed against B-lymphocyte stimulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity investigations in the SD rat following pre- and post-natal exposure to cyclosporin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Transplacental passage of insulin complexed to antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Post-thymectomy autoimmunity: abnormal T-cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

What's so special about the developing immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Functional characterization of N297A, a murine surrogate for low-Fc binding anti-human CD3 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Preclinical development of monoclonal antibodies: considerations for the use of non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental and reproductive toxicology studies in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Cyclosporine induced autoimmunity in newborns prevented by early immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity (DIT) in drug safety testing: matching DIT testing to adverse outcomes and childhood disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Methodologies for developmental immunotoxicity (DIT) testing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Perinatal immunotoxicity: why adult exposure assessment fails to predict risk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Workshop to identify critical windows of exposure for children's health: immune and respiratory systems work group summary

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicology: emerging issues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity of dexamethasone: comparison of fetal versus adult exposures.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in life

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Diethylstilbestrol exposure during fetal development affects thymus: studies in fourteen-month-old mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Applications of immunohistochemistry in the evaluation of immunosuppressive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Prospects for developmental immunotoxicity guidance and an update on ICH S8.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicology and risk assessment: a workshop summary.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity testing: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

A proposed testing framework for developmental immunotoxicology (DIT)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Symposium summary: children's health risk - what's so special about the developing immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Species comparison of anatomical and functional immune system development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental toxicology evaluations--issues with including neurotoxicology and immunotoxicology assessments in reproductive toxicology studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Further evaluation of the incorporation of an immunotoxicological functional assay for assessing humoral immunity for hazard identification purposes in rats in a standard toxicology study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

The comparative immunotoxicity of five selected compounds following developmental or adult exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Consensus workshop on methods to evaluate developmental immunotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity evaluation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental toxicity testing of biopharmaceuticals in nonhuman primates: previous experience and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Maturation of B-Cell Differentiation Ability and T-Cell Regulatory Function in Infancy and Childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Feasibility of human trials to assess developmental immunotoxicity, and some comparison with data on New World monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

T-cell-dependent antibody response: assay development in cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

FcRn: the neonatal Fc receptor comes of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Impaired host resistance to Trichinella spiralis as a consequence of prenatal treatment of rats with diazepam.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Prenatal diazepam induced persisting depression of cellular immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Preclinical safety evaluation using nonrodent species: an industry/welfare project to minimize dog use.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Abnormal thymus development and impaired function of the immune system in rats after prenatal exposure to aciclovir

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental toxicity testing of monoclonal antibodies: an enhanced pre- and postnatal study design option

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Administration of recombinant human stem cell factor (rhSCF) and granulocyte-colony stimulating factor (rhG-CSF) to maternal and fetal rhesus monkeys (Macaca mulatta).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity of di-n-octyltin dichloride (DOTC) in an extended one-generation reproductive toxicity study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity of methylmercury: the relative sensitivity of developmental and immune parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Developmental immunotoxicity in male rats after juvenile exposure to di-n-octyltin dichloride (DOTC).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

Transfer of antibody via mother's milk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

The link between T helper balance and lymphoproliferative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1547691X.2012.661486

10.3109/1547691X.2012.661486

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference