(Q37996291)

26 August 2017

β-Defensins: multifunctional modulators of infection, inflammation and more? (English)

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26 August 2017

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Fiona Semple

1

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PubMed ID

22441423

26 August 2017

Julia R Dorin

series ordinal

2

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26 August 2017

21 March 2012

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26 August 2017

12

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Journal of Innate Immunity

inferred from page(s)

published in

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26 August 2017

4

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26 August 2017

4

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26 August 2017

337-348

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Discovery of alpha-defensins in basal mammals

26 August 2017

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21 January 2018

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21 January 2018

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Evolution of primate theta-defensins: a serpentine path to a sweet tooth

21 January 2018

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Discovery of five conserved beta -defensin gene clusters using a computational search strategy

21 January 2018

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Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity

21 January 2018

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Signal sequence conservation and mature peptide divergence within subgroups of the murine beta-defensin gene family.

21 January 2018

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The complexity of selection at the major primate beta-defensin locus

21 January 2018

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Primate beta-defensins--structure, function and evolution

21 January 2018

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AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

21 January 2018

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The changing of the guard: Molecular diversity and rapid evolution of beta-defensins

21 January 2018

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Defensins and the convergent evolution of platypus and reptile venom genes

21 January 2018

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Allelic recombination between distinct genomic locations generates copy number diversity in human beta-defensins.

21 January 2018

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Psoriasis is associated with increased beta-defensin genomic copy number

21 January 2018

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A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

21 January 2018

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Association of higher DEFB4 genomic copy number with Crohn's disease

21 January 2018

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Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

21 January 2018

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Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

21 January 2018

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The antimicrobial peptide DEFB1 is associated with caries.

21 January 2018

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Single-nucleotide polymorphisms (SNPs) in human beta-defensin 1: high-throughput SNP assays and association with Candida carriage in type I diabetics and nondiabetic controls

21 January 2018

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Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci

21 January 2018

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Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.

21 January 2018

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Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

21 January 2018

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Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

21 January 2018

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Characterization of the mouse beta defensin 1, Defb1, mutant mouse model.

21 January 2018

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beta-Defensin 1 contributes to pulmonary innate immunity in mice

21 January 2018

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Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.

21 January 2018

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Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

21 January 2018

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Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

21 January 2018

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Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3.

21 January 2018

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Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3

21 January 2018

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21 January 2018

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Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.

21 January 2018

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An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis.

21 January 2018

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Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

21 January 2018

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Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.

21 January 2018

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The Toll-like receptor 1/2 agonists Pam(3) CSK(4) and human β-defensin-3 differentially induce interleukin-10 and nuclear factor-κB signalling patterns in human monocytes

21 January 2018

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Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells

21 January 2018

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Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

21 January 2018

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Differential regulation of beta-defensin expression in human skin by microbial stimuli

21 January 2018

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Modulation of human beta-defensin-1 (hBD-1) in plasmacytoid dendritic cells (PDC), monocytes, and epithelial cells by influenza virus, Herpes simplex virus, and Sendai virus and its possible role in innate immunity

21 January 2018

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Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation

21 January 2018

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Use of human reconstructed epidermis to analyze the regulation of beta-defensin hBD-1, hBD-2, and hBD-3 expression in response to LPS

21 January 2018

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Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4.

21 January 2018

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Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family

21 January 2018

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The novel human beta-defensin-3 is widely expressed in oral tissues

21 January 2018

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Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo

21 January 2018

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The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses

21 January 2018

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Endogenous antimicrobial peptides and skin infections in atopic dermatitis

21 January 2018

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Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin

21 January 2018

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Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

21 January 2018

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Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization.

21 January 2018

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Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

21 January 2018

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The novel beta-defensin DEFB123 prevents lipopolysaccharide-mediated effects in vitro and in vivo

21 January 2018

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Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection

21 January 2018

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Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins

21 January 2018

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Interleukin 10 protects mice from lethal endotoxemia

21 January 2018

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Induction of regulatory T cells by a murine β-defensin

21 January 2018

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A -defensin mutation causes black coat color in domestic dogs

21 January 2018

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Molecular and evolutionary history of melanism in North American gray wolves

21 January 2018

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Human beta-defensin-3 promotes wound healing in infected diabetic wounds

21 January 2018

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CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells

21 January 2018

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Defensin Expression by the Cornea: Multiple Signalling Pathways Mediate IL-1β Stimulation of hBD-2 Expression by Human Corneal Epithelial Cells

21 January 2018

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An antimicrobial peptide gene found in the male reproductive system of rats.

21 January 2018

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Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ.

21 January 2018

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Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice

21 January 2018

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Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis

21 January 2018

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The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa

21 January 2018

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Lipopolysaccharide-induced epididymitis disrupts epididymal beta-defensin expression and inhibits sperm motility in rats.

21 January 2018

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An epididymis-specific beta-defensin is important for the initiation of sperm maturation

21 January 2018

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A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility.

21 January 2018

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Beta-defensin 126 on the surface of macaque sperm mediates attachment of sperm to oviductal epithelia

21 January 2018

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Macaque sperm coating protein DEFB126 facilitates sperm penetration of cervical mucus

21 January 2018

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The carbohydrate structure of DEFB126, the major component of the cynomolgus Macaque sperm plasma membrane glycocalyx

21 January 2018

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Beta-defensin 126 on the cell surface protects sperm from immunorecognition and binding of anti-sperm antibodies.

21 January 2018

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Beta-defensin 22 is a major component of the mouse sperm glycocalyx

21 January 2018

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Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells

21 January 2018

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A defensin from tomato with dual function in defense and development

21 January 2018

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Topographical distribution of antimicrobial genes in the zebrafish intestine.

21 January 2018

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Sexually dimorphic gene expression in the developing mouse gonad.

21 January 2018

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EMAGE mouse embryo spatial gene expression database: 2010 update

21 January 2018

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Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product

21 January 2018

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

21 January 2018

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Pattern of mRNA expression of beta-defensins in basal cell carcinoma

21 January 2018

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Loss of human beta-defensin 1, 2, and 3 expression in oral squamous cell carcinoma

21 January 2018

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Molecular classification of renal tumors by gene expression profiling

21 January 2018

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Expression profile of human beta-defensin 3 in oral squamous cell carcinoma.

21 January 2018

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Overexpression of human beta-defensin-3 in oral dysplasia: potential role in macrophage trafficking

21 January 2018

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Human beta-defensin-1, -2, and -3 exhibit opposite effects on oral squamous cell carcinoma cell proliferation

21 January 2018

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Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer

21 January 2018

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Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

21 January 2018

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Antimicrobial human beta-defensin-2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells

21 January 2018

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12 December 2020

Discovery of multiple beta-defensin like homologues in teleost fish

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12 December 2020

Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines

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12 December 2020

Cancer-Specific Loss of β-Defensin 1 in Renal and Prostatic Carcinomas

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12 December 2020

A novel role for defensins in intestinal homeostasis: regulation of IL-1beta secretion

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12 December 2020

Messenger RNA (mRNA) expression for the antimicrobial peptides beta-defensin-1 and beta-defensin-2 in the male rat reproductive tract: beta-defensin-1 mRNA in initial segment and caput epididymidis is regulated by androgens and not bacterial lipopol

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12 December 2020

Clinicopathologic significance of tumor cell-lined vessel and microenvironment in oral squamous cell carcinoma

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12 December 2020

Elevated serum beta-defensins concentrations in patients with lung cancer

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12 December 2020

Evaluation of the effect of human beta-defensins on neutrophil apoptosis

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12 December 2020

Immunization with Bin1b decreases sperm motility with compromised fertility in rats

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12 December 2020

Human beta-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis, and attenuates a pro-inflammatory cytokine response

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12 December 2020

Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity

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12 December 2020

Expression patterns of platypus defensin and related venom genes across a range of tissue types reveal the possibility of broader functions for OvDLPs than previously suspected

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12 December 2020

Identifiers

DOI

10.1159/000336619

1 reference

26 August 2017

1 reference

PubMed ID

22441423