(Q38000156)

26 August 2017

The immune system in the aging human (English)

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26 August 2017

Paulina Dominika Rymkiewicz

1

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26 August 2017

Yi Xiong Heng

2

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26 August 2017

Anusha Vasudev

3

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26 August 2017

Anis Larbi

4

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26 August 2017

1 September 2012

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26 August 2017

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26 August 2017

53

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26 August 2017

1-3

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26 August 2017

235-250

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https://scigraph.springernature.com/pub.10.1007/s12026-012-8289-3

26 August 2017

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cites work

Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans

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https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Nature of the decline in antigen-induced humoral immunity with age.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Tracing thymic output in older individuals.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Thymic involution and immune reconstitution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Thymic involution with ageing: obsolescence or good housekeeping?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Reversal of thymic atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging of the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Signal transduction and functional changes in neutrophils with aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Impairment of SHP-1 down-regulation in the lipid rafts of human neutrophils under GM-CSF stimulation contributes to their age-related, altered functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Baseline total and specific differential white blood cell counts and 5-year all-cause mortality in community-dwelling older women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Impaired in vivo CD4+ T cell expansion and differentiation in aged mice is not solely due to T cell defects: decreased stimulation by aged dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Effect of age on surface molecules and cytokine expression in human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging mice exhibit a functional defect in mucosal dendritic cell response against an intracellular pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Impaired functions of peripheral blood monocyte subpopulations in aged humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Invariant NKT and NKT-like lymphocytes: two different T cell subsets that are differentially affected by ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

NK-like T cells and plasma cytokines, but not anti-viral serology, define immune fingerprints of resilience and mild disability in exceptional aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Natural killer cell function is altered during the primary response of aged mice to influenza infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Gamma/delta T lymphocytes are affected in the elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Skewed representation of functionally distinct populations of Vgamma9Vdelta2 T lymphocytes in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Characterization of naïve, memory and effector CD8+ T cells: effect of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T-cell aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Modulation of human lymphocyte proliferative response with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

T-cell antigen receptor triggering and lipid rafts: a matter of space and time scales. Talking Point on the involvement of lipid rafts in T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Differential role of lipid rafts in the functions of CD4+ and CD8+ human T lymphocytes with aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Plasma membrane microdomains in aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Reversible senescence in human CD4+CD45RA+CD27- memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

The immunology of exceptional individuals: the lesson of centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

B cells in the aged: CD27, CD5, and CD40 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Regulation of aged humoral immune defense against pneumococcal bacteria by IgM memory B cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

A multi-nutrient supplement reduced markers of inflammation and improved physical performance in active individuals of middle to older age: a randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Rac mediates TNF-induced cytokine production via modulation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Inflammatory markers and onset of cardiovascular events: results from the Health ABC study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Metabolic syndrome, inflammation, and incident heart failure in the elderly: the cardiovascular health study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Aging of the immune system as a prognostic factor for human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Seroprevalence of cytomegalovirus infection in the United States, 1988-1994

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Age-associated accumulation of CMV-specific CD8+ T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

The cytomegalovirus-specific CD4+ T-cell response expands with age and markedly alters the CD4+ T-cell repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Cytomegalovirus infection in Gambian infants leads to profound CD8 T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Maintenance of large subpopulations of differentiated CD8 T-cells two years after cytomegalovirus infection in Gambian infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Old age and anti-cytomegalovirus immunity are associated with altered T-cell reconstitution in HIV-1-infected patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Evidence of premature immune aging in patients thymectomized during early childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Frailty is associated with impairment of vaccine-induced antibody response and increase in post-vaccination influenza infection in community-dwelling older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Prevalence and correlates of functional disability in multiethnic elderly Singaporeans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Determinants of successful aging using a multidimensional definition among Chinese elderly in Singapore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Association between C-reactive protein and features of the metabolic syndrome: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Ageing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-012-8289-3

Interleukin-6 and selected plasma proteins in healthy persons of different ages

21 January 2018

1 reference

12 December 2020

Aging affect the anti-tumor potential of dendritic cell vaccination, but it can be overcome by co-stimulation with anti-OX40 or anti-4-1BB

1 reference

12 December 2020

Effect of aging on epidermal dendritic cell populations in C57BL/6J mice

1 reference

12 December 2020

Dendritic cell responsiveness to stimulation with influenza vaccine is unimpaired in old age

1 reference

12 December 2020

Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry

1 reference

12 December 2020

alpha-Interferon cream restores decreased levels of Langerhans/indeterminate (CD1a+) cells in aged and PUVA-treated skin

1 reference

12 December 2020

The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians

1 reference

12 December 2020

Aging and the skin immune system

1 reference

12 December 2020

Thymic involution: effect on T cell differentiation

1 reference

12 December 2020

The SENIEUR protocol after 16 years

1 reference

12 December 2020

Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age

1 reference

12 December 2020

The origins of age-related proinflammatory state

1 reference

12 December 2020

Aging, immunity, and cancer

1 reference

12 December 2020

Tea consumption and cognitive impairment and decline in older Chinese adults.

1 reference

12 December 2020

Changes in the human thymus during aging

1 reference

12 December 2020

Diversity of the Ig repertoire is maintained with age in spite of reduced germinal centre cells in human tonsil lymphoid tissue

1 reference

12 December 2020

Decreased frequency and proliferative response of invariant Vα24Vβ11 natural killer T (iNKT) cells in healthy elderly

1 reference

12 December 2020

Age-associated thymic atrophy in the mouse is due to a deficiency affecting rearrangement of the TCR during intrathymic T cell development.

1 reference

12 December 2020

Vα24+ NKT cells are decreased in elderly humans

1 reference

12 December 2020

Numerical and functional alterations of circulating gammadelta T lymphocytes in aged people and centenarians

1 reference

12 December 2020

Increased cytokine production in mononuclear cells of healthy elderly people

1 reference

12 December 2020

The associations between physical activity and inflammatory markers in high-functioning older persons: MacArthur Studies of Successful Aging

1 reference

12 December 2020

Asthma in older adults: observations from the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) study

1 reference

12 December 2020

Impairment of gamma/delta T lymphocytes in elderly: implications for immunosenescence

1 reference

12 December 2020

1 reference

12 December 2020

Serum total IgE and specific IgE to Dermatophagoides pteronyssinus, but not eosinophil cationic protein, are more likely to be elevated in elderly asthmatic patients.

1 reference

12 December 2020

Interleukin-7 is a critical growth factor in early human T-cell development.

1 reference

12 December 2020

Age-dependent changes in transmembrane signalling: identification of G proteins in human lymphocytes and polymorphonuclear leukocytes

1 reference

12 December 2020

On a causal mechanism of chronic thymic involution in man

1 reference

12 December 2020

10.1007/S12026-012-8289-3

Identifiers

DOI

1 reference

Dimensions Publication ID

26 August 2017

0 references

1 reference