(Q38004366)

26 August 2017

title

The pituitary tumor transforming gene in thyroid cancer (English)

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26 August 2017

4

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26 August 2017

G D Lewy

1

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26 August 2017

N Sharma

2

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26 August 2017

R I Seed

3

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26 August 2017

K Boelaert

5

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26 August 2017

C J McCabe

6

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26 August 2017

publication date

5 April 2012

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Journal of Endocrinological Investigation

26 August 2017

published in

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26 August 2017

volume

35

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26 August 2017

issue

4

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26 August 2017

page(s)

425-433

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Molecular cloning and characterization of the tumor transforming gene (TUTR1): a novel gene in human tumorigenesis

26 August 2017

cites work

1 reference

12 December 2020

Incidence of thyroid cancer in women in relation to reproductive and hormonal factors.

1 reference

12 December 2020

Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer

1 reference

12 December 2020

Structure and chemical inhibition of the RET tyrosine kinase domain

1 reference

12 December 2020

Comparison of nuclear DNA content in primary and metastatic differentiated thyroid carcinoma.

1 reference

12 December 2020

Frequent loss of heterozygosity on chromosomes 3p and 17p without VHL or p53 mutations suggests involvement of unidentified tumor suppressor genes in follicular thyroid carcinoma

1 reference

12 December 2020

Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

1 reference

12 December 2020

Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product

1 reference

12 December 2020

Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)

1 reference

12 December 2020

BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications

1 reference

12 December 2020

Expression of PTTG (pituitary tumor transforming gene) in esophageal cancer

1 reference

12 December 2020

Prognostic significance of RET and NTRK1 rearrangements in sporadic papillary thyroid carcinoma

1 reference

12 December 2020

Mutational screening of RET, HRAS, KRAS, NRAS, BRAF, AKT1, and CTNNB1 in medullary thyroid carcinoma.

1 reference

12 December 2020

Segregating sister genomes: the molecular biology of chromosome separation

1 reference

12 December 2020

Estrogen and thyroid-stimulating hormone (TSH) receptors in neoplastic and nonneoplastic human thyroid tissue

1 reference

12 December 2020

DNA aneuploidy in follicular adenomas of the thyroid gland.

1 reference

12 December 2020

Activation of mitogen-activated protein kinase cascade regulates pituitary tumor-transforming gene transactivation function

1 reference

12 December 2020

1 reference

12 December 2020

Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity.

1 reference

12 December 2020

BRAF mutations in papillary carcinomas of the thyroid

1 reference

12 December 2020

Image analysis of papillary thyroid carcinoma fine-needle aspirates: significant association between aneuploidy and death from disease

1 reference

12 December 2020

Identification of c-myc as a down-stream target for pituitary tumor-transforming gene

1 reference

12 December 2020

BRAF kinase in melanoma development and progression.

1 reference

12 December 2020

Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells

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12 December 2020

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12 December 2020

Promoter mutations are no major cause of PTTG overexpression in pituitary adenomas

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12 December 2020

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

1 reference

12 December 2020

Expression of hpttg proto-oncogene in lymphoid neoplasias

1 reference

12 December 2020

Role and regulation of the fibroblast growth factor axis in human thyroid follicular cells

1 reference

12 December 2020

Increasing incidence of thyroid cancer in the United States, 1973-2002

1 reference

12 December 2020

Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo

1 reference

12 December 2020

Pituitary tumor transforming gene causes aneuploidy and p53-dependent and p53-independent apoptosis.

1 reference

12 December 2020

Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer

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12 December 2020

Molecular evidence for the same clonal origin of multifocal papillary thyroid carcinomas

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12 December 2020

Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis

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12 December 2020

Cancer statistics, 2003.

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12 December 2020

Expression of pituitary-tumour transforming gene in colorectal tumours

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12 December 2020

Activation of the hepatocyte growth factor (HGF)-Met system in papillary thyroid cancer: biological effects of HGF in thyroid cancer cells depend on Met expression levels

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12 December 2020

Regulation of the pituitary tumor transforming gene by insulin-like-growth factor-I and insulin differs between malignant and non-neoplastic astrocytes

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12 December 2020

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

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12 December 2020

RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions.

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12 December 2020

Gene expression profile of human thyroid cancer in relation to its mutational status

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12 December 2020

Database of p53 gene somatic mutations in human tumors and cell lines

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12 December 2020

Apoptosis of human glioma cells in vitro and in vivo induced by a neutralizing antibody against human basic fibroblast growth factor.

1 reference

12 December 2020

hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

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12 December 2020

Specific pattern of RAS oncogene mutations in follicular thyroid tumors

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12 December 2020

Chromosome 1 rearrangements involving the genes TPR and NTRK1 produce structurally different thyroid-specific TRK oncogenes

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12 December 2020

Loss of heterozygosity on chromosome 1p in thyroid adenoma and medullary carcinoma, but not in papillary carcinoma.

1 reference

12 December 2020

Inhibition of pituitary tumor-transforming gene-1 in thyroid cancer cells by drugs that decrease specificity proteins

1 reference

12 December 2020

Prognostic Significance of Human Pituitary Tumor-Transforming Gene Immunohistochemical Expression in Differentiated Thyroid Cancer

1 reference

12 December 2020

RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.

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12 December 2020

Expression of the Na+/I- symporter gene in human thyroid tumors: a comparison study with other thyroid-specific genes

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12 December 2020

Molecular cloning of pituitary tumor transforming gene 1 from ovarian tumors and its expression in tumors

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12 December 2020

A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns]

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12 December 2020

p53, the cellular gatekeeper for growth and division

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12 December 2020

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

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12 December 2020

Isolation and characterization of human thyroid endothelial cells

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12 December 2020

A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

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12 December 2020

Transforming events in thyroid tumorigenesis and their association with follicular lesions

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12 December 2020

Prevalence of Ras mutations in thyroid neoplasia

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12 December 2020

PPARgamma staining as a surrogate for PAX8/PPARgamma fusion oncogene expression in follicular neoplasms: clinicopathological correlation and histopathological diagnostic value

1 reference

12 December 2020

BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and Resistance

1 reference

12 December 2020

Pituitary tumor transforming gene binding factor: a novel transforming gene in thyroid tumorigenesis

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12 December 2020

Differential loss of heterozygosity in the region of the Cowden locus within 10q22-23 in follicular thyroid adenomas and carcinomas

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12 December 2020

PTTG/securin activates expression of p53 and modulates its function

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12 December 2020

Prognostic scoring systems in patients with follicular thyroid cancer: a comparison of different staging systems in predicting the patient outcome

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12 December 2020

RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features.

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12 December 2020

Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a vascular endothelial growth factor/kinase insert domain receptor/inhibitor of DNA binding-3 autocrine pathway

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12 December 2020

Pituitary tumor transforming gene (PTTG) transforming and transactivation activity

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12 December 2020

Oncogenes in thyroid cancer

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12 December 2020

Genetic and biological subgroups of low-stage follicular thyroid cancer

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12 December 2020

Expression pattern of the pendrin and sodium/iodide symporter genes in human thyroid carcinoma cell lines and human thyroid tumors.

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12 December 2020

Insulin and IGF-1 regulate the expression of the pituitary tumor transforming gene (PTTG) in breast tumor cells

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12 December 2020

Vascular endothelial growth factor expression is higher in differentiated thyroid cancer than in normal or benign thyroid

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12 December 2020

Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells

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12 December 2020

Allelotyping of follicular thyroid tumors

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12 December 2020

Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells

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12 December 2020

Expression of pituitary tumor transforming gene (PTTG) and its binding protein in human astrocytes and astrocytoma cells: function and regulation of PTTG in U87 astrocytoma cells

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12 December 2020

Iodide symporter gene expression in human thyroid tumors

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12 December 2020

An intronless homolog of human proto-oncogene hPTTG is expressed in pituitary tumors: evidence for hPTTG family

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12 December 2020

Human pituitary tumor-transforming gene induces angiogenesis

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12 December 2020

A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor-transforming gene product

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12 December 2020

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

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12 December 2020

PTTG and PBF repress the human sodium iodide symporter

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12 December 2020

Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma

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12 December 2020

p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis

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12 December 2020

Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological features

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12 December 2020

Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells.

1 reference

12 December 2020

Genomic instability in sporadic colorectal cancer quantitated by inter-simple sequence repeat PCR analysis

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12 December 2020

Suppression of lung cancer with siRNA targeting PTTG.

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12 December 2020

Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

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12 December 2020

Over-expression of hepatocyte growth factor/scatter factor (HGF/SF) and the HGF/SF receptor (cMET) are associated with a high risk of metastasis and recurrence for children and young adults with papillary thyroid carcinoma

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12 December 2020

A case-control study of thyroid cancer in women under age 55 in Shanghai (People's Republic of China).

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12 December 2020

The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer

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12 December 2020

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

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12 December 2020

Proteolytic balance and capillary morphogenesis

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12 December 2020

ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer.

1 reference

12 December 2020

Allelotype of follicular thyroid carcinomas reveals genetic instability consistent with frequent nondisjunctional chromosomal loss

1 reference

12 December 2020

BRAF V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas

1 reference

12 December 2020

Molecular prognostic markers in papillary and follicular thyroid cancer: Current status and future directions

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12 December 2020

Vascular endothelial growth factor is a secreted angiogenic mitogen

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12 December 2020

BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas

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12 December 2020

Pituitary tumor transforming gene (PTTG) regulates placental JEG-3 cell division and survival: evidence from live cell imaging

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12 December 2020

Transcripts of PTTG and growth factors bFGF and IGF-1 are correlated in pituitary adenomas

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12 December 2020

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

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12 December 2020

Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells

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12 December 2020

Pituitary tumor-transforming gene regulates multiple downstream angiogenic genes in thyroid cancer

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12 December 2020

Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

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12 December 2020

Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis

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12 December 2020

Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors.

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12 December 2020

The Raf/MEK/ERK pathway: new concepts of activation.

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12 December 2020

The PAX8/PPAR gamma fusion oncogene as a potential therapeutic target in follicular thyroid carcinoma

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12 December 2020

Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas

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12 December 2020

Outcomes of patients with differentiated thyroid carcinoma following initial therapy

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12 December 2020

Angiogenesis in endocrine tumors.

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12 December 2020

Well-differentiated thyroid carcinomas: p53 mutation status and microvessel density.

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12 December 2020

Pituitary tumor-transforming gene protein associates with ribosomal protein S10 and a novel human homologue of DnaJ in testicular cells

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12 December 2020

Pathology and genetics of thyroid carcinoma

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12 December 2020

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

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12 December 2020

DNA damage-induced inhibition of securin expression is mediated by p53.

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12 December 2020

Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis

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12 December 2020

Expression of pituitary tumor transforming gene in human gastric carcinoma

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12 December 2020

Thyroid cancer epidemiology and prognostic variables

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12 December 2020

Studies of allelic loss in thyroid tumors reveal major differences in chromosomal instability between papillary and follicular carcinomas

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12 December 2020

Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment

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12 December 2020

Increased expression of the vascular endothelial growth factor is a pejorative prognosis marker in papillary thyroid carcinoma

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12 December 2020

Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression

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12 December 2020

Functional role of estrogen in pituitary tumor pathogenesis

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12 December 2020

The paired box-8/peroxisome proliferator-activated receptor-gamma oncogene in thyroid tumorigenesis

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12 December 2020

Increased angiogenesis in papillary thyroid carcinoma but lack of prognostic importance

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12 December 2020

Clonal origin of non-medullary thyroid tumours assessed by non-random X-chromosome inactivation

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12 December 2020

Thyroid cancer among young women related to prior thyroid disease and pregnancy history

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12 December 2020

Identifiers

DOI

10.3275/8332

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Dimensions Publication ID

26 August 2017

1078551437

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