(Q38005275)

26 August 2017

title

Multipotent mesenchymal stromal cells and the innate immune system (English)

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26 August 2017

Katarina Le Blanc

1

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26 August 2017

Dimitrios Mougiakakos

series ordinal

2

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26 August 2017

publication date

25 April 2012

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Nature Reviews Immunology

26 August 2017

published in

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26 August 2017

volume

12

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26 August 2017

issue

5

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26 August 2017

page(s)

383-396

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Fibroblast Colony Formation from Monolayer Cultures of Blood Cells

26 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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Mesenchymal stromal cells: a novel and effective strategy for facilitating engraftment and accelerating hematopoietic recovery after transplantation?

31 March 2020

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Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy

31 March 2020

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Mesenchymal stem cells remain of host origin even a long time after allogeneic peripheral blood stem cell or bone marrow transplantation.

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Identity and ranking of colonic mesenchymal stromal cells

31 March 2020

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Stem cell in gastrointestinal structure and neoplastic development

31 March 2020

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Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

31 March 2020

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Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

31 March 2020

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Human bone marrow-derived stem cells acquire epithelial characteristics through fusion with gastrointestinal epithelial cells

31 March 2020

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Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type

31 March 2020

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"Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs).

31 March 2020

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Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung

31 March 2020

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Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis

31 March 2020

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Human Nasal Mucosa Contains Tissue-Resident Immunologically Responsive Mesenchymal Stromal Cells

31 March 2020

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Isolation of stem cell populations with trophic and immunoregulatory functions from human intestinal tissues: potential for cell therapy in inflammatory bowel disease

31 March 2020

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Mesenchymal cells of the intestinal lamina propria

31 March 2020

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Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing

31 March 2020

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Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production

31 March 2020

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Exploring the full spectrum of macrophage activation

31 March 2020

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Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile

31 March 2020

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Mesenchymal stem cell homing: the devil is in the details

31 March 2020

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Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6

31 March 2020

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Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages

31 March 2020

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Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation

31 March 2020

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Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

31 March 2020

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The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells

31 March 2020

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Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice

31 March 2020

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Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages.

31 March 2020

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Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury

31 March 2020

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Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells

31 March 2020

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Toll-Like Receptor-3-Activated Human Mesenchymal Stromal Cells Significantly Prolong the Survival and Function of Neutrophils

31 March 2020

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Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche

31 March 2020

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Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

31 March 2020

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Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge

31 March 2020

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Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.

31 March 2020

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Role of mast cells in allergic and non-allergic immune responses: comparison of human and murine data

31 March 2020

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Bone marrow stromal cells inhibit mast cell function via a COX2-dependent mechanism

31 March 2020

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Human gingiva-derived mesenchymal stromal cells attenuate contact hypersensitivity via prostaglandin E2-dependent mechanisms.

31 March 2020

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Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells

31 March 2020

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IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis

31 March 2020

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Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells

31 March 2020

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Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: role of NKp30 and NKG2D receptors

31 March 2020

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Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.

31 March 2020

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Mesenchymal stem cells protect breast cancer cells through regulatory T cells: role of mesenchymal stem cell-derived TGF-beta

31 March 2020

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Interactions between human mesenchymal stem cells and natural killer cells

31 March 2020

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Human mesenchymal stem cells modulate allogeneic immune cell responses

31 March 2020

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Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.

31 March 2020

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Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells.

31 March 2020

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Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways

31 March 2020

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Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells.

31 March 2020

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Th17 T cells: linking innate and adaptive immunity

31 March 2020

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Identification of an innate T helper type 17 response to intestinal bacterial pathogens.

31 March 2020

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31 March 2020

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Interleukin-17A: a T-cell-derived growth factor for murine and human mesenchymal stem cells.

31 March 2020

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Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.

31 March 2020

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Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner

31 March 2020

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Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype.

31 March 2020

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Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor.

31 March 2020

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Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation.

31 March 2020

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Opposing effect of mesenchymal stem cells on Th1 and Th17 cell polarization according to the state of CD4+ T cell activation

31 March 2020

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Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis

31 March 2020

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The role of complement in inflammatory diseases from behind the scenes into the spotlight

31 March 2020

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C3a and C5a are chemotactic factors for human mesenchymal stem cells, which cause prolonged ERK1/2 phosphorylation

31 March 2020

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Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress.

31 March 2020

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Mesenchymal stem cells and their microenvironment

31 March 2020

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Fate of culture-expanded mesenchymal stem cells in the microvasculature: in vivo observations of cell kinetics

31 March 2020

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Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

31 March 2020

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Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses

31 March 2020

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Reduction of N-glycolylneuraminic acid xenoantigen on human adipose tissue-derived stromal cells/mesenchymal stem cells leads to safer and more useful cell sources for various stem cell therapies

31 March 2020

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Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β.

31 March 2020

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Mesenchymal stem cells inhibit complement activation by secreting factor H.

31 March 2020

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Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

31 March 2020

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

31 March 2020

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Toll-like receptor-mediated signaling in human adipose-derived stem cells: implications for immunogenicity and immunosuppressive potential

31 March 2020

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Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R.

31 March 2020

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Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses

31 March 2020

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Toll-like receptors and their ligands control mesenchymal stem cell functions

31 March 2020

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Immunomodulatory properties of mesenchymal stem cells derived from dental pulp and dental follicle are susceptible to activation by toll-like receptor agonists

31 March 2020

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Toll-like receptor triggering in cord blood mesenchymal stem cells

31 March 2020

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Role of toll-like receptors on human adipose-derived stromal cells.

31 March 2020

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Inflammation modifies the pattern and the function of Toll-like receptors expressed by human mesenchymal stromal cells

31 March 2020

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Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors.

31 March 2020

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Role of MyD88 in TLR agonist-induced functional alterations of human adipose tissue-derived mesenchymal stem cells

31 March 2020

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Evidence for the involvement of galectin-3 in mesenchymal stem cell suppression of allogeneic T-cell proliferation

31 March 2020

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Implication of NOD1 and NOD2 for the differentiation of multipotent mesenchymal stem cells derived from human umbilical cord blood

31 March 2020

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Lipopolysaccharides can protect mesenchymal stem cells (MSCs) from oxidative stress-induced apoptosis and enhance proliferation of MSCs via Toll-like receptor(TLR)-4 and PI3K/Akt

31 March 2020

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Toll-like receptor 9 ligands enhance mesenchymal stem cell invasion and expression of matrix metalloprotease-13.

31 March 2020

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Modulation of adult mesenchymal stem cells activity by toll-like receptors: implications on therapeutic potential

31 March 2020

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Osteoblast responses to bacterial pathogens: a previously unappreciated role for bone-forming cells in host defense and disease progression

31 March 2020

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Intravenous administration of 99mTc-HMPAO-labeled human mesenchymal stem cells after stroke: in vivo imaging and biodistribution

31 March 2020

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A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype

31 March 2020

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Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines

31 March 2020

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Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

31 March 2020

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TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

31 March 2020

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Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

31 March 2020

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IFN-γ and TNF-α differentially regulate immunomodulation by murine mesenchymal stem cells

31 March 2020

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IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

31 March 2020

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Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma

31 March 2020

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TLR signaling in the gut in health and disease

31 March 2020

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TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

31 March 2020

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Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase

31 March 2020

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Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37.

31 March 2020

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Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis.

31 March 2020

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Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses

31 March 2020

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A paradoxical role for IFN-gamma in the immune properties of mesenchymal stem cells during viral challenge

31 March 2020

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Bone-marrow-derived mesenchymal stem cells as a target for cytomegalovirus infection: implications for hematopoiesis, self-renewal and differentiation potential

31 March 2020

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Persistence of human parvovirus B19 in multipotent mesenchymal stromal cells expressing the erythrocyte P antigen: implications for transplantation

31 March 2020

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Immunogenicity of Human Mesenchymal Stem Cells in HLA-Class I-Restricted T-Cell Responses Against Viral or Tumor-Associated Antigens

31 March 2020

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Reciprocal interactions between human mesenchymal stem cells and gammadelta T cells or invariant natural killer T cells

31 March 2020

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Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma

31 March 2020

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31 March 2020

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12 December 2020

Marrow microenvironment transfer by heterotopic transplantation of freshly isolated and cultured cells in porous sponges

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12 December 2020

Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche.

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12 December 2020

Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.

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12 December 2020

Limited engraftment capacity of bone marrow-derived mesenchymal cells following T-cell-depleted hematopoietic stem cell transplantation

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12 December 2020

Toll-like receptor triggering in cord blood mesenchymal stem cells

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12 December 2020

Identifiers

DOI

10.1038/NRI3209

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26 August 2017

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