(Q38005397)

26 August 2017

1 reference

title

Tumor progression: potential role of unstable genomic changes (English)

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26 August 2017

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R P Hill

1

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26 August 2017

1 September 1990

1 reference

Cancer and Metastasis Reviews

26 August 2017

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26 August 2017

9

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26 August 2017

2

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26 August 2017

137-147

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https://scigraph.springernature.com/pub.10.1007/bf00046340

26 August 2017

0 references

cites work

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12 December 2020

Cancer metastasis. Organ colonization and the cell-surface properties of malignant cells

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DNA amplification is rare in normal human cells

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Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis

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Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

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Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines

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Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms

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Genetic instability of cancer. Why a metastatic tumor is unstable and a benign tumor is stable

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Involvement of soybean agglutinin binding cells in the lymphatic metastasis of the R3230AC rat mammary adenocarcinoma

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Dynamic heterogeneity: isolation of murine tumor cell populations enriched for metastatic variants and quantification of the unstable expression of the phenotype.

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Amplified pulmonary metastases of a rat rhabdomyosarcoma in response to nitrosourea treatment

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Cytogenetic evidence of gene amplification as a mechanism for tumor cell invasion

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Mechanisms of tumor progression

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Gene amplification in cultured cells

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Normal fibroblasts responding to anoxia exhibit features of the malignant phenotype

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The importance of circular DNA in mammalian gene amplification

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Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells

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Correlation of frequency of induced mutation and metastatic potential in tumor cell lines from a single mouse mammary tumor.

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Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting

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Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.

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Oncogene amplification in tumor cells.

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An experimental model for oncogene activation during tumor progression in vivo

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12 December 2020

Frequencies of independent and simultaneous selection of Chinese hamster cells for methotrexate and doxorubicin (adriamycin) resistance

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12 December 2020

Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma

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Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

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Chromosomal and molecular clues to tumor progression

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12 December 2020

Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression

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12 December 2020

Increased incidence of CAD gene amplification in tumorigenic rat lines as an indicator of genomic instability of neoplastic cells.

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DNA amplification in drug resistant cells and in tumours

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12 December 2020

Evidence for a novel gene associated with low tumor metastatic potential

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12 December 2020

Mechanisms of development of metastases

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12 December 2020

Quantitative genetic analysis of tumor progression

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12 December 2020

Clonal heterogeneity, experimental metastatic ability, and p21 expression in H-ras-transformed NIH 3T3 cells

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12 December 2020

Analysis of gene amplification in human tumor cell lines

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12 December 2020

Tumor suppressor genes: the puzzle and the promise

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12 December 2020

The identification of a neutral glycosphingolipid antigenic marker for metastatic cells in the R3230AC rat mammary adenocarcinoma

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12 December 2020

Gene amplification: an example of accelerated evolution in tumorigenic cells

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12 December 2020

Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells

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Recent progress in understanding mechanisms of mammalian DNA amplification

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12 December 2020

Genetic instability and tumor progression

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12 December 2020

Evidence that beta 1-6 branched Asn-linked oligosaccharides on metastatic tumor cells facilitate invasion of basement membranes

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12 December 2020

Clonal dominance of primary tumours by metastatic cells: genetic analysis and biological implications

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12 December 2020

Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts

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Metastatic Inefficiency

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12 December 2020

Drug resistance in KHT fibrosarcoma cell lines with different metastatic ability

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12 December 2020

Metastatic potential and spontaneous mutation rates: studies with two murine cell lines and their recently induced metastatic variants.

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12 December 2020

Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs

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12 December 2020

Comparison of spontaneous mutation rates of normal and chemically transformed human skin fibroblasts

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12 December 2020

Enhanced metastatic potential of murine fibrosarcomas treated in vitro with ultraviolet radiation.

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12 December 2020

The clonal evolution of tumor cell populations

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12 December 2020

Effects of folate deficiency on the metastatic potential of murine melanoma cells

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12 December 2020

Identifiers

DOI

10.1007/BF00046340

1 reference

PubMed ID

2253313

Dimensions Publication ID

26 August 2017

1017040806

0 references

Fatcat ID

release_dm2f52iyrbhrtmwnpsnkko62qi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dm2f52iyrbhrtmwnpsnkko62qi

24 November 2022

mapped directly with Wikidata item

PubMed ID

2253313

1 reference

PubMed ID

2253313