(Q38005895)

30 June 2019

title

Neuroprotection and estrogen receptors (English)

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30 June 2019

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2

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30 June 2019

author name string

James W Simpkins

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1

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30 June 2019

Courtney Brock

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3

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30 June 2019

Anne M Etgen

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4

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30 June 2019

publication date

14 September 2012

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30 June 2019

published in

Neuroendocrinology

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30 June 2019

volume

96

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30 June 2019

issue

2

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30 June 2019

page(s)

119-130

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30 June 2019

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

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Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats

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17 beta-estradiol protects neurons from ischemic damage and attenuates accumulation of extracellular excitatory amino acids

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The neurotoxic effects of estrogen on ischemic stroke in older female rats is associated with age-dependent loss of insulin-like growth factor-1.

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Neuroprotection by estrogen in animal models of global and focal ischemia

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Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse

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Modulation of the endocannabinoid system by focal brain ischemia in the rat is involved in neuroprotection afforded by 17beta-estradiol

21 January 2018

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Neuronal estrogen receptor-alpha mediates neuroprotection by 17beta-estradiol

21 January 2018

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Estrogen receptor agonists and estrogen attenuate TNF-α-induced apoptosis in VSC4.1 motoneurons

21 January 2018

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MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia

21 January 2018

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Estrogen can act via estrogen receptor alpha and beta to protect hippocampal neurons against global ischemia-induced cell death.

21 January 2018

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Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation

21 January 2018

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Neurosteroid estradiol rescues ischemia-induced deficit in the long-term potentiation of rat hippocampal CA1 neurons

21 January 2018

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C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection

21 January 2018

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Neuroprotective effects of R,R-tetrahydrochrysene against glutamate-induced cell death through anti-excitotoxic and antioxidant actions involving estrogen receptor-dependent and -independent pathways.

21 January 2018

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Estrogen-mediated neuroprotection against beta-amyloid toxicity requires expression of estrogen receptor alpha or beta and activation of the MAPK pathway

21 January 2018

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An ICI 182,780-sensitive, membrane-related estrogen receptor contributes to estrogenic neuroprotective actions against amyloid-beta toxicity.

21 January 2018

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Neuroprotective properties of selective estrogen receptor agonists in cultured neurons.

21 January 2018

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Modulation of Abeta-induced neurotoxicity by estrogen receptor alpha and other associated proteins in lipid rafts

21 January 2018

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Seladin-1 is a fundamental mediator of the neuroprotective effects of estrogen in human neuroblast long-term cell cultures

21 January 2018

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Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against β-amyloid toxicity

21 January 2018

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Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway

21 January 2018

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Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons.

21 January 2018

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Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons

21 January 2018

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Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism

21 January 2018

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Estrogen receptor α and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models

21 January 2018

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Roles of estrogen receptors alpha and beta in sexually dimorphic neuroprotection against glutamate toxicity

21 January 2018

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Oestrogen receptor subtype-specific repression of calpain expression and calpain enzymatic activity in neuronal cells--implications for neuroprotection against Ca-mediated excitotoxicity

21 January 2018

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Oestrogen receptors and signalling pathways: implications for neuroprotective effects of sex steroids in Parkinson's disease

21 January 2018

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Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon

21 January 2018

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Implication of the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in the neuroprotective effect of estradiol in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice

21 January 2018

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Effect of estrogen receptor agonists treatment in MPTP mice: evidence of neuroprotection by an ER alpha agonist

21 January 2018

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17Beta-estradiol differentially protects cortical pericontusional zone from programmed cell death after traumatic cerebral contusion at distinct stages via non-genomic and genomic pathways.

21 January 2018

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Neuroprotection mediated through estrogen receptor-alpha in astrocytes

21 January 2018

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Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro

21 January 2018

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Estrogen provides neuroprotection against activated microglia-induced dopaminergic neuronal injury through both estrogen receptor-alpha and estrogen receptor-beta in microglia

21 January 2018

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17Beta-estradiol prevents retinal ganglion cell loss induced by acute rise of intraocular pressure in rat.

21 January 2018

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Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma.

21 January 2018

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Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta.

21 January 2018

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Estradiol attenuates neuroprotective benefits of isoflurane preconditioning in ischemic mouse brain

21 January 2018

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Neuroprotection by a selective estrogen receptor beta agonist in a mouse model of global ischemia

21 January 2018

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Neuroprotective effects of genistein in Mongolian gerbils: estrogen receptor-β involvement.

21 January 2018

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Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-β.

21 January 2018

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The effects of estradiol on estrogen receptor and glutamate transporter expression in organotypic hippocampal cultures exposed to oxygen--glucose deprivation.

21 January 2018

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Estrogen receptor beta protects against acoustic trauma in mice

21 January 2018

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Neuroprotective effects of genistein in VSC4.1 motoneurons exposed to activated microglial cytokines

21 January 2018

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Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination

21 January 2018

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The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus

21 January 2018

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Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats

21 January 2018

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Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a novel GPR30-dependent Mechanism

21 January 2018

1 reference

Neuroprotective effects of oestrogen against oxidative toxicity through activation of G-protein-coupled receptor 30 receptor.

21 January 2018

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GPR30 is positioned to mediate estrogen effects on basal forebrain cholinergic neurons and cognitive performance

21 January 2018

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Membrane estrogen receptor regulation of hypothalamic function

21 January 2018

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A transmembrane intracellular estrogen receptor mediates rapid cell signaling

21 January 2018

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17alpha-estradiol: a brain-active estrogen?

21 January 2018

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Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo

21 January 2018

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Estrogen protection in Friedreich's ataxia skin fibroblasts

21 January 2018

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The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties

21 January 2018

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Subcellular localization of estrogen receptor beta in mouse hippocampus

21 January 2018

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Role of estrogen receptor alpha in membrane-initiated signaling in neural cells: interaction with IGF-1 receptor

21 January 2018

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Control of CNS neuronal excitability by estrogens via membrane-initiated signaling

21 January 2018

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Estrogen receptor alpha is expressed on the cell-surface of embryonic hypothalamic neurons

21 January 2018

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Estradiol-induced estrogen receptor-alpha trafficking

21 January 2018

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Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes.

21 January 2018

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Estradiol rapidly regulates membrane estrogen receptor alpha levels in hypothalamic neurons

21 January 2018

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Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex.

21 January 2018

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Rapid estrogen signaling in the brain: implications for the fine-tuning of neuronal circuitry

21 January 2018

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Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat striatal neurons

21 January 2018

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17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats

21 January 2018

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Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus

21 January 2018

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Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway

21 January 2018

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Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity

21 January 2018

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Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation

21 January 2018

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Acetylation of the pro-apoptotic factor, p53 in the hippocampus following cerebral ischemia and modulation by estrogen

21 January 2018

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Effects of 3-beta-diol, an androgen metabolite with intrinsic estrogen-like effects, in modulating the aquaporin-9 expression in the rat efferent ductules

21 January 2018

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Rationale for routine and immediate administration of intravenous estrogen for all critically ill and injured patients

21 January 2018

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The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons.

21 January 2018

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12 December 2020

Localization of estrogen receptor beta-immunoreactivity in astrocytes of the adult rat brain

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12 December 2020

Neuroprotective effects of estradiol in the adult rat hippocampus: Interaction with insulin-like growth factor-I signalling

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12 December 2020

Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats

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12 December 2020

Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice.

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12 December 2020

Stroke in estrogen receptor-alpha-deficient mice

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12 December 2020

Estradiol exerts neuroprotective effects when administered after ischemic insult

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12 December 2020

Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons

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12 December 2020

Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites

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12 December 2020

Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury

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12 December 2020

Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke

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12 December 2020

17beta-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: a new neuroprotective pathway

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12 December 2020

Examination of estradiol effects on the rapid estradiol mediated increase in hippocampal synaptic transmission in estrogen receptor alpha knockout mice

1 reference

12 December 2020

Estradiol is a protective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies

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12 December 2020

Effects of hormone replacement therapy on cognitive and brain aging.

1 reference

12 December 2020

ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury.

1 reference

12 December 2020

Estrogen and Parkinson's disease

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12 December 2020

Estrogen stimulates postsynaptic density-95 rapid protein synthesis via the Akt/protein kinase B pathway.

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12 December 2020

The use of estrogens and related compounds in the treatment of damage from cerebral ischemia.

1 reference

12 December 2020

A new, nongenomic estrogen action: the rapid release of intracellular calcium

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12 December 2020

Are estrogens protective or risk factors in brain injury and neurodegeneration? Reevaluation after the Women's health initiative

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12 December 2020

Novel mechanisms for estrogen-induced neuroprotection

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12 December 2020

Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia

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12 December 2020

Decreased mortality in users of estrogen replacement therapy

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12 December 2020

Activation of estrogen receptor-α and of angiotensin-converting enzyme 2 suppresses ischemic brain damage in oophorectomized rats

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12 December 2020

Differential Neuroprotection of Selective Estrogen Receptor Agonists against Autonomic Dysfunction and Ischemic Cell Death in Permanent versus Reperfusion Injury

1 reference

12 December 2020

The four-vessel occlusion rat model: method for complete occlusion of vertebral arteries and control of collateral circulation

1 reference

12 December 2020

Hormone replacement therapy and the risk of stroke. Follow-up of a population-based cohort in Sweden.

1 reference

12 December 2020

Decreased risk of stroke among postmenopausal hormone users. Results from a national cohort

1 reference

12 December 2020

17 beta-Estradiol potentiates kainate-induced currents via activation of the cAMP cascade

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12 December 2020

17 alpha-estradiol exerts neuroprotective effects on SK-N-SH cells

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12 December 2020

Neuroprotection against oxidative stress by estrogens: structure-activity relationship

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12 December 2020

Estrogen and cognitive functioning in women

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12 December 2020

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12 December 2020

Rapid action of 17beta-estradiol on kainate-induced currents in hippocampal neurons lacking intracellular estrogen receptors.

1 reference

12 December 2020

Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways.

1 reference

12 December 2020

Identifiers

DOI

10.1159/000338409

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30 June 2019

PMC publication ID

6507404

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30 June 2019

PubMed publication ID

22538356

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30 June 2019