(Q38008992)

26 August 2017

title

From protein interaction networks to novel therapeutic strategies (English)

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26 August 2017

2

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Samira Jaeger

1

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26 August 2017

publication date

9 May 2012

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volume

64

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issue

6

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page(s)

529-537

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Sequencing technologies - the next generation

26 August 2017

cites work

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Genome annotation: from sequence to biology

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Protein function in the post-genomic era.

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SEX LIMITED INHERITANCE IN DROSOPHILA.

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Surfing the p53 network

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30 years and a long way into p53 research

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The first 30 years of p53: growing ever more complex

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p53 in health and disease

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Awakening guardian angels: drugging the p53 pathway

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Network biology: understanding the cell's functional organization

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Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators.

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A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

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A novel genetic system to detect protein-protein interactions

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A generic protein purification method for protein complex characterization and proteome exploration

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High-quality binary protein interaction map of the yeast interactome network

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Protein-protein interactions essentials: key concepts to building and analyzing interactome networks

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Functional and topological characterization of protein interaction networks

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Network-based prediction of protein function

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Identifying functional modules in protein-protein interaction networks: an integrated exact approach

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Protein complexes and functional modules in molecular networks

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Combining modularity, conservation, and interactions of proteins significantly increases precision and coverage of protein function prediction

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Conserved patterns of protein interaction in multiple species

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The human disease network

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Protein networks in disease

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Unveiling the role of network and systems biology in drug discovery

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A human MAP kinase interactome

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Genome-wide association data reveal a global map of genetic interactions among protein complexes

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Modifier genes convert "simple" Mendelian disorders to complex traits

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Interactome mapping suggests new mechanistic details underlying Alzheimer's disease

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Charting the molecular network of the drug target Bcr-Abl

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A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib

21 January 2018

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Drug repositioning: identifying and developing new uses for existing drugs

21 January 2018

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The price of innovation: new estimates of drug development costs

21 January 2018

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PROMISCUOUS: a database for network-based drug-repositioning

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Drug target identification using side-effect similarity

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Recycling side-effects into clinical markers for drug repositioning

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Oral miltefosine for Indian visceral leishmaniasis

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Thalidomide: tragic past and promising future

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Multicomponent therapeutics for networked systems

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Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer

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Mediators of vascular remodelling co-opted for sequential steps in lung metastasis.

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21 January 2018

Identifiers

DOI

10.1002/IUB.1040

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26 August 2017

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