(Q38011034)

26 August 2017

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title

Extrapolation of animal toxicity to humans: interspecies comparisons in drug development (English)

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26 August 2017

Voisin EM

1

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26 August 2017

Ruthsatz M

series ordinal

2

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26 August 2017

Collins JM

series ordinal

3

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26 August 2017

Hoyle PC

series ordinal

4

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26 August 2017

language of work or name

English

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publication date

1 October 1990

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Regulatory Toxicology and Pharmacology

26 August 2017

published in

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26 August 2017

volume

12

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26 August 2017

issue

2

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26 August 2017

page(s)

107-116

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Quantitative Relations in the Physiological Constitutions of Mammals

26 August 2017

cites work

1 reference

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Pharmacokinetics for regulatory risk analysis: the case of trichloroethylene

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Pharmacokinetics for regulatory risk analysis: the case of 1,1,1-trichloroethane (methyl chloroform).

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7 January 2021

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics.

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7 January 2021

Sources of uncertainty in pharmacokinetic prediction

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7 January 2021

Symposium on clinical drug evaluation and human pharmacology. VI. Difficulties in extrapolating data on metabolism of drugs from animal to man.

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7 January 2021

Review of interspecies risk comparisons

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7 January 2021

Animal extrapolation and the challenge of human heterogeneity.

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7 January 2021

Relevance of experimental studies to human risk

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7 January 2021

Physiologically Based Pharmacokinetic Modeling: Principles and Applications

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Therapeutic Dosage in Small and Large Mammals

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Nonclinical toxicity studies of antiviral drugs indicated for the treatment of non-life-threatening diseases: evaluation of drug toxicity prior to phase 1 clinical studies

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Body size and metabolism

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7 January 2021

Extrapolation of experimental data from animals to man

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7 January 2021

General toxicity testing: sense and non-sense, science and policy

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Relationship of lethal toxic dose to body weight of the mouse

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Altered tissue distribution of amphotericin B by liposomal encapsulation: comparison of normal mice to mice infected with Candida albicans

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7 January 2021

Safety assessments of chemicals with thresholded effects.

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7 January 2021

The value of chronic animal toxicology studies of pharmaceutical compounds: A retrospective analysis.

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7 January 2021

A toxicology databank based on animal safety evaluation studies of pharmaceutical compounds

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7 January 2021

Implications of pharmacokinetic modeling in risk assessment analysis

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7 January 2021

Dosage regimen design for pharmaceutical studies conducted in animals.

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7 January 2021

Man versus beast: pharmacokinetic scaling in mammals

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7 January 2021

Physiologically based pharmacokinetic modeling with methylchloroform: implications for interspecies, high dose/low dose, and dose route extrapolations.

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7 January 2021

In vitro metabolism of methylene chloride in human and animal tissues: use in physiologically based pharmacokinetic models

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7 January 2021

Physiologic pharmacokinetic models and interanimal species scaling

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7 January 2021

Determination of human body surface area from height and weight

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7 January 2021

The role of toxicology in drug research and development

1 reference

https://api.crossref.org/works/10.1016%2FS0273-2300%2805%2980052-2

7 January 2021

Interspecific Scaling of Toxicity Data

1 reference

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7 January 2021

Extrapolation of animal toxicity data to man.

1 reference

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7 January 2021

Lysergic Acid Diethylamide: Its Effects on a Male Asiatic Elephant

1 reference

https://api.crossref.org/works/10.1016%2FS0273-2300%2805%2980052-2

7 January 2021

10.1016/S0273-2300(05)80052-2

Identifiers

DOI

1 reference

26 August 2017

1 reference