(Q38017580)

English

Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases

scientific article published on 10 June 2012

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scholarly article

1 reference

Europe PubMed Central

27 August 2017

Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases (English)

1 reference

Europe PubMed Central

27 August 2017

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author name string

Leonid Tarassishin

1

1 reference

Europe PubMed Central

27 August 2017

Avital Bauman

2

1 reference

Europe PubMed Central

27 August 2017

Hyeon-Sook Suh

3

1 reference

Europe PubMed Central

27 August 2017

Sunhee C Lee

4

1 reference

Europe PubMed Central

27 August 2017

publication date

10 June 2012

1 reference

Europe PubMed Central

27 August 2017

Journal of Neuroimmune Pharmacology

1 reference

Europe PubMed Central

27 August 2017

8

1 reference

Europe PubMed Central

27 August 2017

1

1 reference

Europe PubMed Central

27 August 2017

132-144

1 reference

Europe PubMed Central

27 August 2017

https://scigraph.springernature.com/pub.10.1007/s11481-012-9360-5

0 references

Promoter polymorphisms in the IRF3 gene confer protection against systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Pathogen recognition and innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

MicroRNAs: new regulators of immune cell development and function

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Cytoplasmic DNA innate immune pathways

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

STING-dependent signaling.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Akt/GSK3 signaling in the action of psychotropic drugs

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Host genetic risk factors for West Nile virus infection and disease progression

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

HIV-1 activates macrophages independent of Toll-like receptors

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Primer: inflammasomes and interleukin 1beta in inflammatory disorders

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Immunological and inflammatory functions of the interleukin-1 family

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

IL-1: discoveries, controversies and future directions

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Characterization of retinoic acid-inducible gene-I expression in primary murine glia following exposure to vesicular stomatitis virus

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

MasterCARD: a priceless link to innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Cytidine deamination and resistance to retroviral infection: towards a structural understanding of the APOBEC proteins

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Central roles of NLRs and inflammasomes in viral infection

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Cell type-specific involvement of RIG-I in antiviral response

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interleukin-1, nitric oxide and reactive astrocytes

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Cloning and functional analysis of the human IRF-3 promoter

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: a critical role for IRF3

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Viruses selectively upregulate Toll-like receptors in the central nervous system.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interferon regulatory factor 3-dependent pathways are critical for control of herpes simplex virus type 1 central nervous system infection

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

MicroRNA-155 is induced during the macrophage inflammatory response

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Novel interferon-beta-induced gene expression in peripheral blood cells.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

An autoinflammatory disease due to homozygous deletion of the IL1RN locus

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

TLR3 ligation activates an antiviral response in human fetal astrocytes: a role for viperin/cig5

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interleukin-1 and neuronal injury: mechanisms, modification, and therapeutic potential

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

West Nile virus replication interferes with both poly(I:C)-induced interferon gene transcription and response to interferon treatment

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

TLR3 in antiviral immunity: key player or bystander?

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Hitching RIG to action

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interleukin-1 and inflammatory neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Nuanced roles of cytokines in three major human brain disorders

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Toll-like receptors in CNS viral infections

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

TLR3 and TLR4 are innate antiviral immune receptors in human microglia: role of IRF3 in modulating antiviral and inflammatory response in the CNS.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Aberrant expression of interferon regulatory factor 3 in human lung cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

IFI16 is an innate immune sensor for intracellular DNA

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Negative regulation of interferon-β gene expression during acute and persistent virus infections

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Differential mechanisms of action of interferon-beta and glatiramer aetate in MS.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3

1 reference

https://api.crossref.org/works/10.1007%2FS11481-012-9360-5

21 January 2018

Modulation of astrocyte inducible nitric oxide synthase and cytokine expression by interferon beta is associated with induction and inhibition of interferon gamma-activated sequence binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFNs are critical regulators of IL-1 receptor antagonist and IL-1 expression in human microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta and the autoinflammatory diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia in human disease, with an emphasis on acquired immune deficiency syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22684309

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11481-012-9360-5

1 reference

Europe PubMed Central

27 August 2017

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1 reference

Europe PubMed Central

27 August 2017

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