(Q38025661)

27 August 2017

title

CGRP and NO in the trigeminal system: mechanisms and role in headache generation (English)

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27 August 2017

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Karl Messlinger

1

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27 August 2017

Jochen K Lennerz

series ordinal

2

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27 August 2017

Mirjam Eberhardt

series ordinal

3

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27 August 2017

Michael J M Fischer

series ordinal

4

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27 August 2017

publication date

12 July 2012

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27 August 2017

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27 August 2017

volume

52

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27 August 2017

issue

9

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27 August 2017

page(s)

1411-1427

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Calcitonin gene-related peptide and its role in migraine pathophysiology

27 August 2017

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A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks

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Glyceryl trinitrate induces attacks of migraine without aura in sufferers of migraine with aura

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21 January 2018

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Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack

21 January 2018

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Calcitonin gene-related peptide levels during nitric oxide-induced headache in patients with chronic tension-type headache

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New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

21 January 2018

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CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine.

21 January 2018

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The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs

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21 January 2018

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Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: trigeminal origin and co-existence with substance P.

21 January 2018

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Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Functional immunohistochemistry of neuropeptides and nitric oxide synthase in the nerve fibers of the supratentorial dura mater in an experimental migraine model

21 January 2018

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Alterations in neurokinin A-, substance P- and calcitonin gene-related peptide immunoreactivities in the caudal trigeminal nucleus of the rat following electrical stimulation of the trigeminal ganglion.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Evidence for CGRP re-uptake in rat dura mater encephali

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene related peptide released from dural nerve fibers mediates increase of meningeal blood flow in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Tumor necrosis factor-alpha stimulation of calcitonin gene-related peptide expression and secretion from rat trigeminal ganglion neurons

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Repression of stimulated calcitonin gene-related peptide secretion by topiramate

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Characterization of the prostanoid receptor types involved in mediating calcitonin gene-related peptide release from cultured rat trigeminal neurones

21 January 2018

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Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Regulation of calcitonin gene-related peptide secretion from trigeminal nerve cells by botulinum toxin type A: implications for migraine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide stimulation of nitric oxide synthesis and release from trigeminal ganglion glial cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Nitric oxide releases calcitonin-gene-related peptide from rat dura mater encephali promoting increases in meningeal blood flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Nitric oxide regulation of calcitonin gene-related peptide gene expression in rat trigeminal ganglia neurons.

21 January 2018

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The use of nitric oxide donors in pharmacological studies.

21 January 2018

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Nitric oxide activates TRP channels by cysteine S-nitrosylation.

21 January 2018

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TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation

21 January 2018

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Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.

21 January 2018

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Pharmacology of receptors for calcitonin gene-related peptide and amylin

21 January 2018

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CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors.

21 January 2018

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Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: implications for the pathophysiology of migraine

21 January 2018

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Mast cell degranulation activates a pain pathway underlying migraine headache

21 January 2018

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Interaction of calcitonin gene-related peptide, nitric oxide and histamine release in neurogenic blood flow and afferent activation in the rat cranial dura mater.

21 January 2018

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Modulation of dural nociceptor mechanosensitivity by the nitric oxide-cyclic GMP signaling cascade

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Localization and effects of neuropeptide Y, vasoactive intestinal polypeptide, substance P, and calcitonin gene-related peptide in human temporal arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Neurogenically Mediated Plasma Extravasation in Dura Mater: Effect of Ergot Alkaloids: A Possible Mechanism of Action in Vascular Headache

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Sumatriptan inhibits neurogenic vasodilation of dural blood vessels in the anaesthetized rat--intravital microscope studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Increase of meningeal blood flow after electrical stimulation of rat dura mater encephali: mediation by calcitonin gene‐related peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Intravital microscope studies on the effects of neurokinin agonists and calcitonin gene-related peptide on dural vessel diameter in the anaesthetized rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Measurement of meningeal blood vessel diameter in vivo with a plug-in for ImageJ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide mediates nitroglycerin and sodium nitroprusside-induced vasodilation in feline cerebral arterioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

The nonpeptide calcitonin gene-related peptide receptor antagonist BIBN4096BS lowers the activity of neurons with meningeal input in the rat spinal trigeminal nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti-nociceptive potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Calcitonin gene-related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Kainate receptors are primarily postsynaptic to SP-containing axon terminals in the trigeminal dorsal horn

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Presynaptic NMDA receptors modulate glutamate release from primary sensory neurons in rat spinal cord dorsal horn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Biphasic response to nitric oxide of spinal trigeminal neurons with meningeal input in rat--possible implications for the pathophysiology of headaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Nitric oxide synthase inhibition lowers activity of neurons with meningeal input in the rat spinal trigeminal nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Nitric oxide potentiates response of trigeminal neurones to dural or facial stimulation in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Systemic nitroglycerin induces Fos immunoreactivity in brainstem and forebrain structures of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Nitric oxide synthase inhibition: a new principle in the treatment of migraine attacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Lack of efficacy of the selective iNOS inhibitor GW274150 in prophylaxis of migraine headache.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Does the unfavorable pharmacokinetic and pharmacodynamic profile of the iNOS inhibitor GW273629 lead to inefficacy in acute migraine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

A pivotal role of nitric oxide in migraine pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1526-4610.2012.02212.X

10.1111/J.1526-4610.2012.02212.X

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference