(Q38027074)

30 June 2019

title

The EYA-SO/SIX complex in development and disease (English)

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30 June 2019

author name string

Pin-Xian Xu

series ordinal

1

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30 June 2019

publication date

19 July 2012

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30 June 2019

published in

Pediatric Nephrology

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30 June 2019

volume

28

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30 June 2019

issue

6

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30 June 2019

page(s)

843-854

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30 June 2019

A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The zebrafish eya1 gene and its expression pattern during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six class homeobox genes in drosophila belong to three distinct families and are involved in head development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The Caenorhabditis elegans Six/sine oculis class homeobox gene ceh-32 is required for head morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Homologs of animal eyes absent (eya) genes are found in higher plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

sine oculis in basal Metazoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 is required for the early organogenesis of mammalian kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The role of Six1 in mammalian auditory system development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

EYA4, a novel vertebrate gene related to Drosophila eyes absent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eyes absent represents a class of protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The transcription factor Eyes absent is a protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Structure, function and expression of a murine homeobox protein AREC3, a homologue of Drosophila sine oculis gene product, and implication in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Identification and expression of six family genes in mouse retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Autoregulatory binding sites in the zebrafish six3a promoter region define a new recognition sequence for Six3 proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Impaired interactions between mouse Eyal harboring mutations found in patients with branchio-oto-renal syndrome and Six, Dach, and G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Multiple roles of the eyes absent gene in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

EYA1 expression in the developing inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six3 activation of Pax6 expression is essential for mammalian lens induction and specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 controls patterning of the mouse otic vesicle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The transcription factor six1 inhibits neuronal and promotes hair cell fate in the developing zebrafish (Danio rerio) inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Evolutionary origins of vertebrate placodes: insights from developmental studies and from comparisons with other deuterostomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Induction and specification of cranial placodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Mutations of a human homologue of the Drosophila eyes absent gene (EYA1) detected in patients with congenital cataracts and ocular anterior segment anomalies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

EYA1 mutation in a newborn female presenting with cardiofacial syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Branchio-oto-renal syndrome associated mutations in Eyes Absent 1 result in loss of phosphatase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Holoprosencephaly: clinical, anatomic, and molecular dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The six family of homeobox genes in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The cellular basis of kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Kidney morphogenesis: cellular and molecular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Sequential cell and tissue interactions governing organogenesis of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Early organogenesis of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Coordinating early kidney development: lessons from gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Genes and proteins in renal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Renal branching morphogenesis: concepts, questions, and recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

GDNF/Ret signaling and the development of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Advances in early kidney specification, development and patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Frequency of the branchio-oto-renal (BOR) syndrome in children with profound hearing loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Branchio-oto-renal syndrome: reduced penetrance and variable expressivity in four generations of a large kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Phenotypic manifestations of branchio-oto-renal syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

SIX2 and BMP4 mutations associate with anomalous kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

A transcriptional chain linking eye specification to terminal determination of cone cells in the Drosophila eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

The transcription factor Six2 activates expression of the Gdnf gene as well as its own promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Quantitative proteomic identification of six4 as the trex-binding factor in the muscle creatine kinase enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

Tbx18 regulates the development of the ureteral mesenchyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-012-2246-1

A conserved blueprint for the eye?

21 January 2018

1 reference

12 December 2020

Six family genes--structure and function as transcription factors and their roles in development

1 reference

12 December 2020

Tissue-specific regulation of retinal and pituitary precursor cell proliferation

1 reference

12 December 2020

A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10

1 reference

12 December 2020

Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice

1 reference

12 December 2020

Expression of zebrafish six1 during sensory organ development and myogenesis.

1 reference

12 December 2020

SIX3 mutations with holoprosencephaly

1 reference

12 December 2020

Evolution of the gene families forming the Pax/Six regulatory network: isolation of genes from primitive animals and molecular phylogenetic analyses

1 reference

12 December 2020

Regulation of the innate immune response by threonine-phosphatase of Eyes absent

1 reference

12 December 2020

Homeobox genes and connective tissue patterning

1 reference

12 December 2020

sine oculis is a homeobox gene required for Drosophila visual system development

1 reference

12 December 2020

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.

1 reference

12 December 2020

Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode

1 reference

12 December 2020

BOR and BO syndromes are allelic defects of EYA1

1 reference

12 December 2020

A binding site for nuclear receptors is required for the differential expression of the aldolase A fast-twitch muscle promoter in body and head muscles

1 reference

12 December 2020

Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila

1 reference

12 December 2020

Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.

1 reference

12 December 2020

10.1007/S00467-012-2246-1

Identifiers

DOI

1 reference

30 June 2019

Dimensions Publication ID

1012332914

0 references

Fatcat ID

release_gjfss4odh5hyvlscshznkojcue

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gjfss4odh5hyvlscshznkojcue

24 November 2022

mapped directly with Wikidata item

PMC publication ID

6592036

1 reference

30 June 2019

PubMed publication ID

22806561

1 reference

30 June 2019