(Q38027948)

27 August 2017

title

Choosing and using Drosophila models to characterize modifiers of Huntington's disease (English)

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27 August 2017

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Edward W Green

1

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27 August 2017

Flaviano Giorgini

series ordinal

2

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27 August 2017

publication date

1 August 2012

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Biochemical Society Transactions

27 August 2017

published in

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27 August 2017

volume

40

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27 August 2017

issue

4

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27 August 2017

page(s)

739-745

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Huntingtin: a single bait hooks many species

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Huntington's disease: the case for genetic modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

A cell-based screen for drugs to treat Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

A putative Drosophila homolog of the Huntington's disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

A kinder, gentler genetic analysis of behavior: dissection gives way to modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Genetic Transformation of Drosophila with Transposable Element Vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

GAL4 system in Drosophila: a fly geneticist's Swiss army knife

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

The commonly used marker ELAV is transiently expressed in neuroblasts and glial cells in the Drosophila embryonic CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Aging causes distinct characteristics of polyglutamine amyloids in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Refinement of tools for targeted gene expression in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Fly models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Tetracycline-inducible systems for Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

P element insertion-dependent gene activation in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Gal4 in the Drosophila female germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120072

21 January 2018

Identifiers

DOI

10.1042/BST20120072

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27 August 2017

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