(Q38034269)

27 August 2017

title

At the crossroad of T cells, adipose tissue, and diabetes (English)

1 reference

27 August 2017

Giuseppe Matarese

1

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27 August 2017

Claudio Procaccini

series ordinal

2

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27 August 2017

Veronica De Rosa

series ordinal

3

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27 August 2017

publication date

1 September 2012

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27 August 2017

published in

Immunological Reviews

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27 August 2017

volume

249

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27 August 2017

issue

1

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27 August 2017

page(s)

116-134

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Leptin and the regulation of body weight in mammals

27 August 2017

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Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

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Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

21 January 2018

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Leptin Regulates Functional Capacities of Polymorphonuclear Neutrophils

21 January 2018

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Leptin indirectly activates human neutrophils via induction of TNF-alpha

21 January 2018

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Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia

21 January 2018

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High-dose leptin activates human leukocytes via receptor expression on monocytes.

21 January 2018

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Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis

21 January 2018

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Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines

21 January 2018

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Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation

21 January 2018

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Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.

21 January 2018

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Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis

21 January 2018

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Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.

21 January 2018

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Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor

21 January 2018

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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

21 January 2018

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Serum leptin levels in patients with nonalcoholic steatohepatitis.

21 January 2018

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Thyroid hormones influence serum leptin levels in patients with Graves' disease during suppression of beta-adrenergic receptors

21 January 2018

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Leptin consumption in the inflamed joints of patients with rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Immune cells in adipose tissue: key players in metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Type 2 diabetes as an inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Normalization of obesity-associated insulin resistance through immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

21 January 2018

Expanding mTOR signaling

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The AMP-activated protein kinase pathway--new players upstream and downstream.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Foxo: in command of T lymphocyte homeostasis and tolerance

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Regulatory T cells and immune tolerance

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Elevated serum leptin concentrations induced by experimental acute inflammation.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Measurement of the serum leptin level could assist disease activity monitoring in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Glucose-dependent regulation of cholesterol ester metabolism in macrophages by insulin and leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin signaling and obesity: cardiovascular consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Murine models to investigate the influence of diabetic metabolism on the development of atherosclerosis and restenosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin and adipocytokines: bridging the gap between immunity and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Plasma plasminogen activator inhibitor-I is associated with plasma leptin irrespective of body mass index, body fat mass, and plasma insulin and metabolic parameters in premenopausal women.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Plasma leptin levels are associated with abnormal fibrinolysis in men and postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin increase is associated with markers of the hemostatic system in obese healthy women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin and renal fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: potential role in glomerulosclerosis [seecomments]

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The evolving role of leptin and adiponectin in chronic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Adipocytokines and liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Synergistic induction of nitric oxide synthase type II: in vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The weight of leptin in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Decreased CD4+ lymphocyte activation and increased interleukin-4 production in peripheral blood of rheumatoid arthritis patients after acute starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Serum leptin levels in women with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Body size and risk of MS in two cohorts of US women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin modulates the survival of autoreactive CD4+ T cells through the nutrient/energy-sensing mammalian target of rapamycin signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin: a pivotal mediator of intestinal inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Leptin-deficient mice are protected from accelerated nephrotoxic nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

mTOR signalling and metabolic regulation of T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The liver kinase B1 is a central regulator of T cell development, activation, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

SirT1 regulates energy metabolism and response to caloric restriction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Calorie restriction--the SIR2 connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Apoptosis of lymphocytes in allograft in a rat liver transplantation model induced by resveratrol

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

21 January 2018

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Interplay between FOXO, TOR, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The cunning little vixen: Foxo and the cycle of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Foxo transcription factors control regulatory T cell development and function

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

ERRalpha: a metabolic function for the oldest orphan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Nutritional programming of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

A frameshift mutation in human MC4R is associated with a dominant form of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

A frameshift mutation in MC4R associated with dominantly inherited human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Profound obesity associated with a balanced translocation that disrupts the SIM1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Large, rare chromosomal deletions associated with severe early-onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Through thick and thin: wasting, obesity, and TNF alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Adipocytokines and the metabolic complications of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Direct and macrophage-mediated actions of fatty acids causing insulin resistance in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Role of macrophage tissue infiltration in obesity and insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Does hypothalamic inflammation cause obesity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Obesity in psoriasis: the metabolic, clinical and therapeutic implications. Report of an interdisciplinary conference and review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Thyroid function and structure are affected in childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Fuel utilization by hypothalamic neurons: roles for ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Inflammation and endoplasmic reticulum stress in obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Beta-cell failure as a complication of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Regulatory T-cell immunity and its relevance to atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Testing the accelerator hypothesis: the relationship between body mass and age at diagnosis of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Increasing body weight predicts the earlier onset of insulin-dependant diabetes in childhood: testing the 'accelerator hypothesis' (2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The 'accelerator hypothesis': relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9,248 German and Austrian children with type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Higher body weight is associated with earlier onset of Type 1 diabetes in children: confirming the 'Accelerator Hypothesis'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes--indication of an increased environmental pressure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The accelerator hypothesis and increasing incidence of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Insulin resistance is a risk factor for progression to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

No evidence for genetically determined alteration in insulin secretion or sensitivity predisposing to type 1 diabetes: a study of identical twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Can we slow the rising incidence of childhood-onset autoimmune diabetes? The overload hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Thyroid autoimmunity in children with features of both type 1 and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Multidimensional genome scans identify the combinations of genetic loci linked to diabetes-related phenotypes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The NOD mouse model of type 1 diabetes: as good as it gets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The NOD mouse: a model of immune dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Suppression of experimental autoimmune encephalomyelitis by ghrelin

21 January 2018

1 reference

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Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo.

21 January 2018

1 reference

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Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis

21 January 2018

1 reference

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Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis

21 January 2018

1 reference

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Calorie restriction and cancer prevention: metabolic and molecular mechanisms

21 January 2018

1 reference

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Experimental allergic encephalomyelitis in male Lewis rats subjected to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction

21 January 2018

1 reference

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The intricate interface between immune system and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Effect of low saturated fat diet in early and late cases of multiple sclerosis.

21 January 2018

1 reference

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The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

21 January 2018

1 reference

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Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders

21 January 2018

1 reference

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Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

The role of depot fat in the hypothalamic control of food intake in the rat.

21 January 2018

1 reference

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Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

21 January 2018

1 reference

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Obesity, increased linear growth, and risk of type 1 diabetes in children

21 January 2018

1 reference

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Identification of a monoclonal antibody against the leptin receptor that acts as an antagonist and blocks human monocyte and T cell activation

21 January 2018

1 reference

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T-ing up inflammation in fat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01154.X

Elevated Leptin Levels Are Associated with Excess Gains in Fat Mass in Girls, But Not Boys, with Type 1 Diabetes: Longitudinal Study during Adolescence

21 January 2018

1 reference

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Serum Leptin Concentrations in Endometriosis

21 January 2018

1 reference

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10.1111/J.1600-065X.2012.01154.X

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference