(Q38037192)

27 August 2017

title

Human cathelicidin LL-37 prevents bacterial biofilm formation (English)

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27 August 2017

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Andreas S Jacobsen

1

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27 August 2017

Håvard Jenssen

series ordinal

2

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27 August 2017

publication date

1 August 2012

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Future Medicinal Chemistry

27 August 2017

published in

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27 August 2017

volume

4

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27 August 2017

issue

12

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27 August 2017

page(s)

1587-1599

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The clinical impact of bacterial biofilms

27 August 2017

cites work

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Staphylococcus epidermidis infections.

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Activity of antimicrobial peptides in the presence of polysaccharides produced by pulmonary pathogens

21 January 2018

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Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.

21 January 2018

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Human antimicrobial peptides: defensins, cathelicidins and histatins

21 January 2018

1 reference

Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domain

21 January 2018

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LL-37, the only human member of the cathelicidin family of antimicrobial peptides

21 January 2018

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Structural, functional analysis and localization of the human CAP18 gene

21 January 2018

1 reference

The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes

21 January 2018

1 reference

Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles

21 January 2018

1 reference

Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity

21 January 2018

1 reference

Anti-microbial activity of human CAP18 peptides.

21 January 2018

1 reference

Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells

21 January 2018

1 reference

Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide

21 January 2018

1 reference

hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules

21 January 2018

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Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

21 January 2018

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Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium

21 January 2018

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Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori

21 January 2018

1 reference

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection

21 January 2018

1 reference

The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa

21 January 2018

1 reference

The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface

21 January 2018

1 reference

FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis

21 January 2018

1 reference

Biochemical and antibacterial analysis of human wound and blister fluid

21 January 2018

1 reference

Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin.

21 January 2018

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Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

21 January 2018

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Cathelicidin antimicrobial peptides are expressed in salivary glands and saliva

21 January 2018

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Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina

21 January 2018

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Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense

21 January 2018

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Antimicrobial and antibiofilm activity of cathelicidins and short, synthetic peptides against Francisella

21 January 2018

1 reference

Elicitation of epithelial cell-derived immune effectors by outer membrane vesicles of nontypeable Haemophilus influenzae

21 January 2018

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Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic

21 January 2018

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Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells

21 January 2018

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Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1.

21 January 2018

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PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells

21 January 2018

1 reference

Regulation of cathelicidin gene expression: induction by lipopolysaccharide, interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection.

21 January 2018

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Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis

21 January 2018

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Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study.

21 January 2018

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Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

21 January 2018

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The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders

21 January 2018

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Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases

21 January 2018

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Antimicrobial peptide LL-37 is upregulated in chronic nasal inflammatory disease.

21 January 2018

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Antimicrobial protein hCAP18/LL-37 is highly expressed in breast cancer and is a putative growth factor for epithelial cells.

21 January 2018

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Sensitivity of Actinobacillus actinomycetemcomitans and Capnocytophaga spp. to the bactericidal action of LL-37: a cathelicidin found in human leukocytes and epithelium

21 January 2018

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Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus

21 January 2018

1 reference

Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia

21 January 2018

1 reference

Kostmann syndrome or infantile genetic agranulocytosis, part one: celebrating 50 years of clinical and basic research on severe congenital neutropenia

21 January 2018

1 reference

Expression of cathelicidin in recurrent throat infection.

21 January 2018

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Salivary antimicrobial peptide expression and dental caries experience in children

21 January 2018

1 reference

In vitro assessment of antimicrobial peptides as potential agents against several oral bacteria

21 January 2018

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Susceptibility of various oral bacteria to antimicrobial peptides and to phagocytosis by neutrophils.

21 January 2018

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Effect of salt on the interactions of antimicrobial peptides with zwitterionic lipid bilayers.

21 January 2018

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NaCl and sugar release, salivation and taste during mastication of salted chewing gum.

21 January 2018

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Candidacidal effects of two antimicrobial peptides: histatin 5 causes small membrane defects, but LL-37 causes massive disruption of the cell membrane

21 January 2018

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Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection.

21 January 2018

1 reference

Serum 25-hydroxyvitamin d and the incidence of acute viral respiratory tract infections in healthy adults

21 January 2018

1 reference

Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren

21 January 2018

1 reference

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

21 January 2018

1 reference

Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37

21 January 2018

1 reference

Evaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides.

21 January 2018

1 reference

Human cathelicidin (LL-37), a multifunctional peptide, is expressed by ocular surface epithelia and has potent antibacterial and antiviral activity

21 January 2018

1 reference

Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum

21 January 2018

1 reference

Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins

21 January 2018

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Effects of cathelicidin and its fragments on three key enzymes of HIV-1.

21 January 2018

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Impact of LL-37 on anti-infective immunity.

21 January 2018

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LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

21 January 2018

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A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis

21 January 2018

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Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells

21 January 2018

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The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes

21 January 2018

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Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells

21 January 2018

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A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release

21 January 2018

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21 January 2018

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Dental plaque as a biofilm

21 January 2018

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21 January 2018

Dental plaque formation

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Staphylococcus epidermidis isolated from newborn infants express pilus-like structures and are inhibited by the cathelicidin-derived antimicrobial peptide LL37.

21 January 2018

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Natural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus

21 January 2018

1 reference

Role of curli fimbriae in mediating the cells of enterohaemorrhagic Escherichia coli to attach to abiotic surfaces.

21 January 2018

1 reference

Curli fibers are required for development of biofilm architecture in Escherichia coli K-12 and enhance bacterial adherence to human uroepithelial cells

21 January 2018

1 reference

Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli

21 January 2018

1 reference

Human host defense peptide LL-37 prevents bacterial biofilm formation

21 January 2018

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Susceptibility of Pseudomonas aeruginosa Biofilm to Alpha-Helical Peptides: D-enantiomer of LL-37

21 January 2018

1 reference

Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide

21 January 2018

1 reference

Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development

21 January 2018

1 reference

A component of innate immunity prevents bacterial biofilm development

21 January 2018

1 reference

Defensins: antimicrobial peptides of innate immunity

21 January 2018

1 reference

Dermcidin: a novel human antibiotic peptide secreted by sweat glands

21 January 2018

1 reference

A peptide antibiotic from human skin

21 January 2018

1 reference

Innate antimicrobial peptide protects the skin from invasive bacterial infection

21 January 2018

1 reference

Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities

21 January 2018

1 reference

Structure, Dynamics, and Antimicrobial and Immune Modulatory Activities of Human LL-23 and Its Single-Residue Variants Mutated on the Basis of Homologous Primate Cathelicidins

21 January 2018

1 reference

Use of antimicrobial peptides against microbial biofilms: advantages and limits

21 January 2018

1 reference

Extraction of the synthetic lytic peptide, cecropin B, from biological fluid and analysis using reversed-phase high-performance liquid chromatography.

21 January 2018

1 reference

Structure-based design of an indolicidin peptide analogue with increased protease stability

21 January 2018

1 reference

Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity

21 January 2018

1 reference

The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.

21 January 2018

1 reference

All-D-magainin: chirality, antimicrobial activity and proteolytic resistance.

21 January 2018

1 reference

Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide.

21 January 2018

1 reference

Antimicrobial β-peptides and α-peptoids.

21 January 2018

1 reference

Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides

21 January 2018

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Antimicrobial peptoids are effective against Pseudomonas aeruginosa biofilms

21 January 2018

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Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure

21 January 2018

1 reference

Patient-reported outcomes in adults with type 2 diabetes using mealtime inhaled technosphere insulin and basal insulin versus premixed insulin.

21 January 2018

1 reference

Helix induction in antimicrobial peptides by alginate in biofilms

21 January 2018

1 reference

Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model

21 January 2018

1 reference

On-resin cleavage of bacterially expressed fusion proteins for purification of active recombinant peptides SK-29, KR-20, LL-29, and LL-23 from human sweat or skin

21 January 2018

1 reference

An investigation on the antibacterial, cytotoxic, and antibiofilm efficacy of starch-stabilized silver nanoparticles

21 January 2018

1 reference

Developmental pathway for biofilm formation in curli-producing Escherichia coli strains: role of flagella, curli and colanic acid

21 January 2018

1 reference

Human cathelicidin peptide LL37 inhibits both attachment capability and biofilm formation ofStaphylococcus epidermidis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/FMC.12.97

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27 August 2017

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