(Q38037881)

27 August 2017

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title

Clinical pharmacokinetics of ciprofloxacin (English)

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27 August 2017

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Vance-Bryan K

1

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27 August 2017

Guay DR

series ordinal

2

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27 August 2017

Rotschafer JC

series ordinal

3

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27 August 2017

publication date

1 December 1990

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Clinical Pharmacokinetics

27 August 2017

published in

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27 August 2017

volume

19

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27 August 2017

issue

6

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27 August 2017

page(s)

434-461

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https://scigraph.springernature.com/pub.10.2165/00003088-199019060-00003

27 August 2017

exact match

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cites work

Toxicological studies on pipemidic acid. V. Effect on diarthrodial joints of experimental animals

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12 December 2020

Site-specific cleavage of DNA by E. coli DNA gyrase

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12 December 2020

The effect of sucralfate pretreatment on the pharmacokinetics of ciprofloxacin

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12 December 2020

Ciprofloxacin and antacids

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12 December 2020

Ciprofloxacin concentrations in human fluids and tissues following a single oral dose.

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12 December 2020

Drug-drug interactions affecting fluoroquinolones

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12 December 2020

An investigation of the hydrophobicity of the quinolones

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12 December 2020

Clinical experience with ciprofloxacin in the USA.

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12 December 2020

Effect of dose size on bioavailability of ciprofloxacin

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12 December 2020

Ofloxacin and antacids

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12 December 2020

In vitro activity of ciprofloxacin against gram-positive cocci.

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12 December 2020

Reduced enteral absorption of ciprofloxacin in the presence of antacids

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12 December 2020

Inhibition of enoxacin absorption by antacids or ranitidine

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12 December 2020

Effect of norfloxacin on theophylline pharmacokinetics at steady state

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12 December 2020

Concentrations of ciprofloxacin in serum and prostatic tissue in patients undergoing transurethral resection

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12 December 2020

Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli

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12 December 2020

Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

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12 December 2020

Ciprofloxacin in the treatment of infections caused by gentamicin-resistant gram-negative bacteria.

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12 December 2020

In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus

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12 December 2020

Safety of ciprofloxacin based on phase IV studies ("Anwendungsbeobachtung") in the Federal Republic of Germany

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12 December 2020

The in-vitro activity of ciprofloxacin compared with that of norfloxacin and nalidixic acid.

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12 December 2020

Enhanced renal excretion of dicloxacillin in patients with cystic fibrosis

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12 December 2020

Multiple-dose pharmacokinetics of ciprofloxacin administered intravenously to normal volunteers

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12 December 2020

Enoxacin--a potent inhibitor of theophylline metabolism.

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12 December 2020

Overview of preclinical studies with ciprofloxacin

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12 December 2020

Enoxacin raises plasma theophylline concentrations

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12 December 2020

Inhibition of theophylline clearance by coadministered ofloxacin without alteration of theophylline effects

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12 December 2020

Ciprofloxacin distribution in prostatic tissue and fluid following oral administration

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12 December 2020

Pharmacokinetics of single-dose oral ciprofloxacin in patients undergoing chronic ambulatory peritoneal dialysis

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12 December 2020

Pharmacokinetics of ciprofloxacin in cystic fibrosis

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12 December 2020

Comparative studies on interaction between theophylline and quinolones

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12 December 2020

Elimination of plasmids by new 4-quinolones

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12 December 2020

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12 December 2020

Isolation and characterization of norfloxacin-resistant mutants of Escherichia coli K-12.

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12 December 2020

Pharmacokinetics of ciprofloxacin after oral and intravenous administration in healthy volunteers

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12 December 2020

Pharmacokinetics of ciprofloxacin tablets in renal failure; influence of haemodialysis

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12 December 2020

Safety of oral ciprofloxacin. An update based on clinical trial results

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12 December 2020

In vitro activity of Ro 23-6240, a new difluoroquinolone derivative, compared with that of other antimicrobial agents

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12 December 2020

High-performance liquid chromatographic method for determination of ciprofloxacin in biological fluids

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12 December 2020

Intraperitoneal penetration of ciprofloxacin

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12 December 2020

Transfer of ciprofloxacin to bile and determination of biliary metabolites in humans

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12 December 2020

In vitro study with ciprofloxacin: interpretive criteria of agar diffusion test according to standards of the NCCLS and DIN.

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12 December 2020

Antimicrobial activity of ciprofloxacin against Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus determined by the killing curve method: antibiotic comparisons and synergistic interactions

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12 December 2020

Intraprostatic concentrations of ciprofloxacin after intravenous administration

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12 December 2020

Comparative in vitro activities of several new fluoroquinolones and beta-lactam antimicrobial agents against community isolates of Streptococcus pneumoniae

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12 December 2020

[Ciprofloxacine: evaluation of its biliary elimination in man]

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12 December 2020

The importance of pharmacodynamics in determining the dosing interval in therapy for experimental pseudomonas endocarditis in the rat

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12 December 2020

Rapid selection of organisms with increasing resistance on subinhibitory concentrations of norfloxacin in agar

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12 December 2020

Concentrations of ciprofloxacin in human liver, gallbladder, and bile after oral administration.

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12 December 2020

Bacterial resistance to fluoroquinolones

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12 December 2020

Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration

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12 December 2020

In vitro activities of the quinolone antimicrobial agents A-56619 and A-56620.

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12 December 2020

The theophylline-enoxacin interaction: I. Effect of enoxacin dose size on theophylline disposition

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12 December 2020

Determination of ciprofloxacin in biological samples by reversed-phase high performance liquid chromatography

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12 December 2020

Pharmacokinetics of Ciprofloxacin in the Elderly

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12 December 2020

Isolation and structural elucidation of urinary metabolites of ciprofloxacin

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12 December 2020

The in-vitro activities of enoxacin and ofloxacin compared with that of ciprofloxacin

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12 December 2020

Concentration of ciprofloxacin in human serum, lung and pleural tissues and fluids during and after lung surgery

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12 December 2020

Effect of norfloxacin on theophylline metabolism

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12 December 2020

Mode of action of the quinolone antimicrobial agents.

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12 December 2020

Safety of intravenous ciprofloxacin. A review

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12 December 2020

Pharmacokinetics of oral ciprofloxacin, 100 mg single dose, in volunteers and elderly patients

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12 December 2020

A clinically significant interaction between ciprofloxacin and theophylline

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12 December 2020

Pharmacokinetics and pharmacodynamics of ciprofloxacin in cystic fibrosis patients

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12 December 2020

In vitro activity of ciprofloxacin, a new carboxyquinoline antimicrobial agent

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12 December 2020

Ciprofloxacin pharmacokinetics in patients with cystic fibrosis

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12 December 2020

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

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12 December 2020

Aqueous humor penetration of ciprofloxacin in the human eye.

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12 December 2020

In vitro activity of ciprofloxacin (Bay o 9867)

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12 December 2020

Antibacterial activities of ciprofloxacin, norfloxacin, oxolinic acid, cinoxacin, and nalidixic acid

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12 December 2020

Gyrase-inhibitors impair caffeine elimination in man

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12 December 2020

New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay

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12 December 2020

Dose- and sex-independent disposition of ciprofloxacin

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12 December 2020

Disposition of tobramycin in patients with cystic fibrosis: a prospective controlled study

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12 December 2020

Concentration of ciprofloxacin in human prostatic tissue after oral administration

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12 December 2020

Norfloxacin and warfarin

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12 December 2020

Comparative pharmacokinetics of theophylline following two fluoroquinolones co-administration

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12 December 2020

Cross resistance to ciprofloxacin and other antimicrobial agents among clinical isolates of Acinetobacter calcoaceticus biovar anitratus

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12 December 2020

Biology of bacterial deoxyribonucleic acid topoisomerases

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12 December 2020

Comparison of high-pressure liquid chromatography and microbiological assay for the determination of biliary elimination of ciprofloxacin in humans

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12 December 2020

Evaluation of the effect of norfloxacin on the pharmacokinetics of theophylline

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12 December 2020

Effect of ferrous sulfate and multivitamins with zinc on absorption of ciprofloxacin in normal volunteers

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12 December 2020

Interaction between oral ciprofloxacin and caffeine in normal volunteers

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12 December 2020

Antibacterial activity of the metabolites of ciprofloxacin and its significance in the bioassay.

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12 December 2020

Ciprofloxacin concentrations in tonsils following single or multiple administrations

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12 December 2020

Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents

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12 December 2020

Renal elimination of sulfo-ciprofloxacin, a new metabolite of ciprofloxacin

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12 December 2020

Impact of ciprofloxacin on theophylline clearance and steady-state concentrations in serum

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12 December 2020

Pharmacokinetics of ciprofloxacin and effect of repeated dosage on salivary and fecal microflora

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12 December 2020

Ciprofloxacin concentrations and impact of the colon microflora in patients undergoing colorectal surgery

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12 December 2020

New nalidixic acid resistance mutations related to deoxyribonucleic acid gyrase activity.

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12 December 2020

An overview of the pharmacology of intravenously administered ciprofloxacin

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12 December 2020

Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes.

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12 December 2020

Comparative in vitro activity of five quinoline derivatives and five other antimicrobial agents used in oral therapy

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12 December 2020

Pharmacokinetics of single dose intravenous ciprofloxacin in patients undergoing gastrointestinal surgery

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12 December 2020

Ciprofloxacin concentrations in tonsils following a single intravenous infusion

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12 December 2020

The 4-quinolone antibiotics: past, present, and future

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12 December 2020

Ciprofloxacin biliary disposition in cholecystectomised patients with special references to HPLC and bioassay data

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12 December 2020

New synthetic quinolone antibacterial agents and serum concentration of theophylline

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12 December 2020

The pharmacokinetics of ciprofloxacin in patients with impaired renal function

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12 December 2020

Ciprofloxacin-induced hematuria

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12 December 2020

Ciprofloxacin penetration into lungs

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12 December 2020

4-quinolones inhibit biotransformation of caffeine

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12 December 2020

Pharmacokinetics of ciprofloxacin in the elderly: increased oral bioavailability and reduced renal clearance

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12 December 2020

Possible interaction between ciprofloxacin and warfarin

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12 December 2020

Penetration of ciprofloxacin into kidney, fat, muscle and skin tissue

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12 December 2020

Inhibition of norfloxacin absorption by antacids

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12 December 2020

Ofloxacin and warfarin

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12 December 2020

Tissue penetration of ciprofloxacin after single and multiple doses

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12 December 2020

Cyclosporine (cyclosporin A) pharmacokinetics in renal transplant patients receiving ciprofloxacin

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12 December 2020

Ciprofloxacin pharmacokinetics in patients with normal and impaired renal function

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12 December 2020

Single and multiple dose pharmacokinetics of oral ciprofloxacin in elderly patients

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12 December 2020

Relationships between renal function and disposition of oral ciprofloxacin

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12 December 2020

Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria

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12 December 2020

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12 December 2020

Penetration of ciprofloxacin into cerebrospinal fluid of patients with bacterial meningitis

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12 December 2020

Effect of multiple dose oral ciprofloxacin on the pharmacokinetics of theophylline and indocyanine green

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12 December 2020

Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

1 reference

12 December 2020

In-vitro activity of ofloxacin, a quinolone carboxylic acid compared to other quinolones and other antimicrobial agents

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12 December 2020

Differences in susceptibility to quinolones of outer membrane mutants of Salmonella typhimurium and Escherichia coli

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12 December 2020

Tissue penetration and metabolism of ciprofloxacin

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12 December 2020

In-vitro selection of bacteria resistant to the 4-quinolone agents.

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12 December 2020

Efficacy, safety, and potential economic benefits of oral ciprofloxacin in the treatment of infections

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12 December 2020

Diffusion of ciprofloxacin into prostatic fluid

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12 December 2020

Recent advances in pharmaceutical chemistry. The 4-quinolone antibiotics

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12 December 2020

Inhibition of Micrococcus luteus DNA gyrase by norfloxacin and 10 other quinolone carboxylic acids

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12 December 2020

Pharmacokinetics of intravenously administered ciprofloxacin in patients with various degrees of renal function

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12 December 2020

Dose ranging study and constant infusion evaluation of ciprofloxacin

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12 December 2020

Post-antibiotic suppressive effect of ciprofloxacin against gram-positive and gram-negative bacteria.

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12 December 2020

Effect of dose on serum pharmacokinetics of intravenous ciprofloxacin with identification and characterization of extravascular compartments using noncompartmental and compartmental pharmacokinetic models

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12 December 2020

The in vitro and in vivo activity of ciprofloxacin

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12 December 2020

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

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12 December 2020

Ciprofloxacin disk susceptibility tests: interpretive zone size standards for 5-microgram disks

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12 December 2020

Single-dose pharmacokinetics of oral ciprofloxacin in patients with cystic fibrosis

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12 December 2020

Pharmacokinetics of ciprofloxacin in elderly subjects

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12 December 2020

Pharmacokinetics and tolerance of ciprofloxacin after sequential increasing oral doses

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12 December 2020

Determination of ciprofloxacin and its 7-ethylenediamine metabolite in human serum and urine by high-performance liquid chromatography

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12 December 2020

DNA gyrase (Topoisomerase II) from Pseudomonas aeruginosa.

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12 December 2020

Single and multiple dose pharmacokinetics of ciprofloxacin in gynecological tissues

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12 December 2020

Ciprofloxacin and antacids

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12 December 2020

Multiple-dose ciprofloxacin dose ranging and kinetics

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12 December 2020

Ciprofloxacin: multiple-dose pharmacokinetic and clinical results in patients with hypercrinic bronchopulmonary diseases

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12 December 2020

Clinical isolate of Citrobacter freundii highly resistant to new quinolones

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12 December 2020

In vitro activity of CI-934 compared with ciprofloxacin, enoxacin, norfloxacin, and vancomycin

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12 December 2020

Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth

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12 December 2020

Ciprofloxacin increases serum levels of theophylline

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12 December 2020

Effect of quinolones on caffeine disposition

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12 December 2020

DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acid

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12 December 2020

Antibiotic use in cystic fibrosis.

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12 December 2020

Changes in the pharmacokinetics of ciprofloxacin and fecal flora during administration of a 7-day course to human volunteers

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12 December 2020

Pharmacokinetics and tissue penetration of ciprofloxacin

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12 December 2020

Ciprofloxacin pharmacokinetics after a standard or high-fat/high-calcium breakfast

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12 December 2020

Biochemical characteristics and physiological significance of major DNA topoisomerases

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12 December 2020

Pharmacokinetics of ciprofloxacin after oral and parenteral administration

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12 December 2020

Pharmacokinetics of three oral formulations of ciprofloxacin

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12 December 2020

The influence of chronic administration of calcium carbonate on the bioavailability of oral ciprofloxacin.

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12 December 2020

In vitro activity of enoxacin, a quinolone carboxylic acid, compared with those of norfloxacin, new beta-lactams, aminoglycosides, and trimethoprim

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12 December 2020

Pharmacokinetics in the elderly. Studies on ciprofloxacin.

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12 December 2020

Sucralfate reduces the gastrointestinal absorption of norfloxacin

1 reference

12 December 2020

Pharmacokinetics of ciprofloxacin in peripheral lymph and skin blisters

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12 December 2020

In-vitro studies with ciprofloxacin, a new 4-quinolone compound.

1 reference

12 December 2020

In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid

1 reference

12 December 2020

Ciprofloxacin: chemistry, mechanism of action, resistance, antimicrobial spectrum, pharmacokinetics, clinical trials, and adverse reactions

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12 December 2020

Tissue distribution of ciprofloxacin following oral and intravenous administration

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12 December 2020

Adverse effects of the fluoroquinolones.

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12 December 2020

Absolute oral bioavailability of ciprofloxacin

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12 December 2020

Pharmacokinetics of two dosage regimens of ciprofloxacin during a two-week therapeutic trial in patients with cystic fibrosis

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12 December 2020

Pharmacokinetics of intravenously administered ciprofloxacin

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12 December 2020

Comparative evaluation of recently developed quinolone compounds--with a note on the frequency of resistant mutants.

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12 December 2020

Quinolones, theophylline, and diclofenac interactions with the gamma-aminobutyric acid receptor

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12 December 2020

Multiple-dose pharmacokinetics and safety of ciprofloxacin in normal volunteers

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12 December 2020

In-vitro activity of newer quinolones against aerobic bacteria.

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12 December 2020

Enoxacin decreases the clearance of theophylline in man.

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12 December 2020

Intraprostatic concentration of ciprofloxacin and its activity against urinary pathogens

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12 December 2020

Synergistic nephrotoxicity due to ciprofloxacin and cyclosporine

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12 December 2020

Pharmacokinetics of ciprofloxacin

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12 December 2020

Comparative in vitro activities of pefloxacin, ofloxacin, enoxacin and ciprofloxacin against 256 clinical isolates

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12 December 2020

Co-administration of ciprofloxacin and cyclosporin: lack of evidence for a pharmacokinetic interaction

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12 December 2020

Ciprofloxacin in acute exacerbations of chronic bronchitis

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12 December 2020

Penetration of ciprofloxacin into bronchial secretions

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12 December 2020

The theophylline-enoxacin interaction: II. Changes in the disposition of theophylline and its metabolites during intermittent administration of enoxacin

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12 December 2020

In vitro activity of ciprofloxacin compared with those of other new fluorinated piperazinyl-substituted quinoline derivatives

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12 December 2020

Suspected ciprofloxacin-induced interstitial nephritis.

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12 December 2020

Escherichia coli K-12 Mutants Resistant to Nalidixic Acid: Genetic Mapping and Dominance Studies

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12 December 2020

Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile

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12 December 2020

Pharmacokinetics of intravenous ciprofloxacin at three different doses

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12 December 2020

Pharmacokinetics of ciprofloxacin in acutely ill and convalescent elderly patients

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12 December 2020

Contribution of permeability and sensitivity to inhibition of DNA synthesis in determining susceptibilities of Escherichia coli, Pseudomonas aeruginosa, and Alcaligenes faecalis to ciprofloxacin

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12 December 2020

Mechanisms of action of and resistance to ciprofloxacin

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12 December 2020

Oral ciprofloxacin therapy of infections due to Pseudomonas aeruginosa

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12 December 2020

Evaluation of the in vitro bactericidal action of ciprofloxacin on cells of Escherichia coli in the logarithmic and stationary phases of growth

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12 December 2020

Liquid chromatographic determination of ciprofloxacin and some metabolites in human body fluids

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12 December 2020

Use of ciprofloxacin in the treatment of Pseudomonas aeruginosa infections

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12 December 2020

Multiple-dose ciprofloxacin kinetics in normal subjects

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12 December 2020

Pharmacokinetics of ciprofloxacin in healthy volunteers after oral and intravenous administration.

1 reference

12 December 2020

Possible interaction of ciprofloxacin with cyclosporin A

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12 December 2020

A Survey of Clinical Experience with Ciprofloxacin, a New Quinolone Antimicrobial

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12 December 2020

Ciprofloxacin Penetration in Pancreatic Juice

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12 December 2020

Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens

1 reference

12 December 2020

Ofloxacin: antibacterial activity, induction of resistance and killing curves

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12 December 2020

Ciprofloxacin: an overview of adverse experiences

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12 December 2020

Comparison of high-pressure liquid chromatography and bioassay for determination of ciprofloxacin in serum and urine

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12 December 2020

The influence of quinolone derivatives on theophylline clearance

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12 December 2020

Site-specific interaction of DNA gyrase with DNA

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12 December 2020

Effect of lomefloxacin on theophylline pharmacokinetics

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12 December 2020

10.2165/00003088-199019060-00003

Identifiers

DOI

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Dimensions Publication ID

27 August 2017

1024055665

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