(Q38038452)

27 August 2017

title

Digital PCR strategies in the development and analysis of molecular biomarkers for personalized medicine (English)

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27 August 2017

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personalized medicine

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Elizabeth Day

1

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27 August 2017

Paul H Dear

series ordinal

2

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27 August 2017

Frank McCaughan

series ordinal

3

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27 August 2017

publication date

19 August 2012

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27 August 2017

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27 August 2017

volume

59

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27 August 2017

issue

1

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27 August 2017

page(s)

101-107

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

27 August 2017

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Happy mapping: linkage mapping using a physical analogue of meiosis

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Principle and applications of digital PCR

7 January 2021

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Mathematical analysis of copy number variation in a DNA sample using digital PCR on a nanofluidic device

7 January 2021

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Interrogation of genomes by molecular copy-number counting (MCC).

7 January 2021

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Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

7 January 2021

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Evaluation of digital PCR for absolute DNA quantification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Evaluation of a droplet digital polymerase chain reaction format for DNA copy number quantification

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Single molecule detection in nanofluidic digital array enables accurate measurement of DNA copy number

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

BEAMing up for detection and quantification of rare sequence variants.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Development of personalized tumor biomarkers using massively parallel sequencing

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Absolute quantitative detection of ABL tyrosine kinase domain point mutations in chronic myeloid leukemia using a novel nanofluidic platform and mutation-specific PCR.

7 January 2021

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Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

7 January 2021

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Inferring tumor progression from genomic heterogeneity

7 January 2021

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Relative impact of nucleotide and copy number variation on gene expression phenotypes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Taking qPCR to a higher level: Analysis of CNV reveals the power of high throughput qPCR to enhance quantitative resolution

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

7 January 2021

Megapixel digital PCR.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Microdissection molecular copy-number counting (microMCC)--unlocking cancer archives with digital PCR

7 January 2021

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Comprehensive human genome amplification using multiple displacement amplification

7 January 2021

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Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.

7 January 2021

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Sensitive quantitation of minimal residual disease in chronic myeloid leukemia using nanofluidic digital polymerase chain reaction assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Digital PCR provides sensitive and absolute calibration for high throughput sequencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Effect of sustained elevated temperature prior to amplification on template copy number estimation using digital polymerase chain reaction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Genomic evidence of pre-invasive clonal expansion, dispersal and progression in bronchial dysplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Biomarkers of response to epidermal growth factor receptor inhibitors in Non-Small-Cell Lung Cancer Working Group: standardization for use in the clinical trial setting.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

High-resolution characterization of a hepatocellular carcinoma genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Genetic variegation of clonal architecture and propagating cells in leukaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Cell-free nucleic acids as biomarkers in cancer patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Digital PCR for the molecular detection of fetal chromosomal aneuploidy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Implementing prenatal diagnosis based on cell-free fetal DNA: accurate identification of factors affecting fetal DNA yield

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Universal noninvasive detection of solid organ transplant rejection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Copy number variants and pharmacogenomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Genomics and drug response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Quantification noise in single cell experiments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Clinical outcome prediction by microRNAs in human cancer: a systematic review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

MicroRNAs in metabolism and metabolic disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Comprehensive microRNA expression profiling of the hematopoietic hierarchy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

A decade of exploring the cancer epigenome - biological and translational implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

The implications of heterogeneous DNA methylation for the accurate quantification of methylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Single molecule epigenetic analysis in a nanofluidic channel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Digital PCR on a SlipChip

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Studying copy number variations using a nanofluidic platform

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Spinning disk platform for microfluidic digital polymerase chain reaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

High-throughput quantitative polymerase chain reaction in picoliter droplets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

CONTRA: copy number analysis for targeted resequencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Comprehensive qPCR profiling of gene expression in single neuronal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

10.1016/J.YMETH.2012.08.001

7 January 2021

Identifiers

DOI

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27 August 2017

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