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Wnt pathway regulation of embryonic stem cell self-renewal
scientific article published on September 2012
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
title
Wnt pathway regulation of embryonic stem cell self-renewal
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
main subject
stem cell self-renewal
1 reference
based on heuristic
inferred from title
author name string
Bradley J Merrill
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
publication date
1 September 2012
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
published in
Cold Spring Harbor Perspectives in Biology
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
volume
4
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
issue
9
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
page(s)
a007971
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
cites work
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6 September 2017
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
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6 September 2017
Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
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6 September 2017
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.
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6 September 2017
The transcriptional and signalling networks of pluripotency
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6 September 2017
A PiggyBac-based recessive screening method to identify pluripotency regulators
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6 September 2017
Control of the embryonic stem cell state
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6 September 2017
Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/β-catenin signaling and competence provider for Brachyury induction
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A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency.
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Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling
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6 September 2017
Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression
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Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation
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Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules
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6 September 2017
Non-cell-autonomous stimulation of stem cell proliferation following ablation of Tcf3.
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6 September 2017
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
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6 September 2017
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.
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6 September 2017
Metastable pluripotent states in NOD-mouse-derived ESCs
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6 September 2017
Klf4 reverts developmentally programmed restriction of ground state pluripotency
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6 September 2017
Epigenetic reprogramming and induced pluripotency
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6 September 2017
Wnt signaling mediates self-organization and axis formation in embryoid bodies
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PubMed Central
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6 September 2017
Promotion of reprogramming to ground state pluripotency by signal inhibition
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PubMed Central
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6 September 2017
Back and forth between cell fate specification and movement during vertebrate gastrulation
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PubMed Central
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6 September 2017
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
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PubMed Central
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6 September 2017
Chromosomal transposition of PiggyBac in mouse embryonic stem cells
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6 September 2017
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
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PubMed Central
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6 September 2017
The ground state of embryonic stem cell self-renewal
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PubMed Central
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6 September 2017
Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal
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PubMed Central
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6 September 2017
T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways
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6 September 2017
An extended transcriptional network for pluripotency of embryonic stem cells
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6 September 2017
Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
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PubMed Central
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6 September 2017
Nanog safeguards pluripotency and mediates germline development
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PubMed Central
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6 September 2017
Derivation of pluripotent epiblast stem cells from mammalian embryos
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PubMed Central
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6 September 2017
New cell lines from mouse epiblast share defining features with human embryonic stem cells
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PubMed Central
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6 September 2017
POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos
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PubMed Central
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6 September 2017
Diversity of LEF/TCF action in development and disease
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6 September 2017
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
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PubMed Central
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6 September 2017
Dissecting self-renewal in stem cells with RNA interference
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PubMed Central
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6 September 2017
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
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PubMed Central
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6 September 2017
Core transcriptional regulatory circuitry in human embryonic stem cells
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PubMed Central
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6 September 2017
Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos
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6 September 2017
Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development
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PubMed Central
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6 September 2017
Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
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PubMed Central
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6 September 2017
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.
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6 September 2017
Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells
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6 September 2017
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
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6 September 2017
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
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PubMed Central
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6 September 2017
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
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PubMed Central
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6 September 2017
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
1 reference
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PubMed Central
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6 September 2017
GSK-3: tricks of the trade for a multi-tasking kinase
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6 September 2017
Multipotent cell lineages in early mouse development depend on SOX2 function
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6 September 2017
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
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6 September 2017
Brachyury is a target gene of the Wnt/beta-catenin signaling pathway
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PubMed Central
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6 September 2017
Requirement for beta-catenin in anterior-posterior axis formation in mice
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6 September 2017
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
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PubMed Central
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6 September 2017
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
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PubMed Central
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6 September 2017
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
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6 September 2017
Embryonic stem cell lines derived from human blastocysts
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6 September 2017
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
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PubMed Central
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6 September 2017
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
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PubMed Central
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6 September 2017
Lack of beta-catenin affects mouse development at gastrulation
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6 September 2017
LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor
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6 September 2017
Establishment in culture of pluripotential cells from mouse embryos
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6 September 2017
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
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6 September 2017
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
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6 September 2017
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
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6 September 2017
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130
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6 September 2017
Clonal analysis of epiblast fate during germ layer formation in the mouse embryo.
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PubMed Central
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6 September 2017
Oncostatin M binds the high-affinity leukemia inhibitory factor receptor
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6 September 2017
β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
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PubMed Central
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14 September 2017
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells
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PubMed Central
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14 September 2017
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
1 reference
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PubMed Central
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14 September 2017
Beta-catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells
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PubMed Central
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14 September 2017
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
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14 September 2017
Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells
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14 September 2017
Beta-catenin signaling is required for neural differentiation of embryonic stem cells
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14 September 2017
Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
14 September 2017
Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
23 June 2018
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
23 June 2018
Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
23 June 2018
Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
23 June 2018
Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
A core Klf circuitry regulates self-renewal of embryonic stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
An autoradiographic analysis of tissue potency in different regions of the embryonic ectoderm during gastrulation in the mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Histogenetic and neoplastic potential of different regions of the mouse embryonic egg cylinder.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428775
retrieved
31 August 2018
Identifiers
DOI
10.1101/CSHPERSPECT.A007971
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
PMCID
3428775
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
PubMed ID
22952393
1 reference
stated in
Europe PubMed Central
PMCID
3428775
retrieved
27 August 2017
ResearchGate publication ID
230804945
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