(Q38052872)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23074044%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

FLT4/VEGFR3 and Milroy disease: novel mutations, a review of published variants and database update (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23074044%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

0 references

1

1 reference

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15 February 2020

Pia Ostergaard

11

1 reference

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15 February 2020

author name string

Sarah L Spiden

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23074044%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Fiona C Connell

3

1 reference

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15 February 2020

Glen Brice

4

1 reference

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15 February 2020

Sally Cottrell

5

1 reference

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15 February 2020

John Short

6

1 reference

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15 February 2020

Rohan Taylor

7

1 reference

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15 February 2020

Steve Jeffery

8

1 reference

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15 February 2020

Peter S Mortimer

9

1 reference

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15 February 2020

Sahar Mansour

10

1 reference

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15 February 2020

publication date

16 October 2012

1 reference

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15 February 2020

1 reference

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15 February 2020

volume

34

1 reference

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15 February 2020

issue

1

1 reference

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15 February 2020

page(s)

23-31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23074044%20AND%20SRC:MED&resulttype=core&format=json

Vascular endothelial growth factor D is dispensable for development of the lymphatic system

15 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Milroy disease and the VEGFR-3 mutation phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

A new classification system for primary lymphatic dysplasias based on phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Analysis of the coding regions of VEGFR3 and VEGFC in Milroy disease and other primary lymphoedemas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Identification of eight novel VEGFR-3 mutations in families with primary congenital lymphoedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Mapping of primary congenital lymphedema to the 5q35.3 region

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Hereditary lymphedema: evidence for linkage and genetic heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

LOVD: easy creation of a locus-specific sequence variation database using an "LSDB-in-a-box" approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Sox18 induces development of the lymphatic vasculature in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Sporadic in utero generalized edema caused by mutations in the lymphangiogenic genes VEGFR3 and FOXC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Recessive primary congenital lymphoedema caused by a VEGFR3 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

VEGFR3 gene structure, regulatory region, and sequence polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

A model for gene therapy of human hereditary lymphedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Development of the zebrafish lymphatic system requires VEGFC signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Lymphatic dysfunction, not aplasia, underlies Milroy disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Biological basis of therapeutic lymphangiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Lymphatic vascular morphogenesis in development, physiology, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

MutationTaster evaluates disease-causing potential of sequence alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Wide clinical spectrum in a family with hereditary lymphedema type I due to a novel missense mutation in VEGFR3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Lymphangiogenesis: Molecular mechanisms and future promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Improving sequence variant descriptions in mutation databases and literature using the Mutalyzer sequence variation nomenclature checker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Molecular cloning of a novel vascular endothelial growth factor, VEGF-D

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Live imaging of lymphatic development in the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Three children with Milroy disease and de novo mutations in VEGFR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Hereditary lymphedema type I associated with VEGFR3 mutation: the first de novo case and atypical presentations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Growth Factor Therapy and Autologous Lymph Node Transfer in Lymphedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

Functional Analysis of FLT4 Mutations Associated with Nonne–Milroy Lymphedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

A novel VEGFR3 mutation causes Milroy disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

7 January 2021

Segregation analyses and a genome-wide linkage search confirm genetic heterogeneity and suggest oligogenic inheritance in some Milroy congenital primary lymphedema families

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

7 January 2021

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

7 January 2021

Clinical variability in a Japanese hereditary lymphedema type I family with an FLT4 mutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

7 January 2021

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

7 January 2021

Identification of a novel VEGFR-3 missense mutation in a Chinese family with hereditary lymphedema type I

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22223

7 January 2021

Identifiers

DOI

10.1002/HUMU.22223

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23074044%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23074044%20AND%20SRC:MED&resulttype=core&format=json