(Q38054535)

27 August 2017

title

Mechanisms of mesenchymal stromal cell immunomodulation (English)

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27 August 2017

1

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27 August 2017

publication date

23 October 2012

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Immunology & Cell Biology

27 August 2017

published in

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27 August 2017

volume

91

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27 August 2017

issue

1

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27 August 2017

page(s)

19-26

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https://scigraph.springernature.com/pub.10.1038/icb.2012.56

27 August 2017

exact match

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cites work

Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Administration of bone marrow stromal cells ameliorates experimental autoimmune myasthenia gravis by altering the balance of Th1/Th2/Th17/Treg cell subsets through the secretion of TGF-β

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Pathogen recognition and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Sterile inflammation: sensing and reacting to damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Inflammation 2010: new adventures of an old flame

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

C3a and C5a are chemotactic factors for human mesenchymal stem cells, which cause prolonged ERK1/2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

IL1β induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Evidence for the involvement of galectin-3 in mesenchymal stem cell suppression of allogeneic T-cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells inhibit complement activation by secreting factor H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Emerging roles for multipotent, bone marrow-derived stromal cells in host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Macrophage plasticity and polarization: in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Interferon-gamma does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Prostaglandins as modulators of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human mesenchymal stem cells modulate allogeneic immune cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton's Jelly and bone marrow sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Bone marrow stromal cells inhibit mast cell function via a COX2-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Immunomodulation of delayed-type hypersensitivity responses by mesenchymal stem cells is associated with bystander T cell apoptosis in the draining lymph node.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Plasticity of CD4+ T cell lineage differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cell effects on T-cell effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stromal cells: facilitators of successful transplantation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Allogeneic mesenchymal stem cells: agents of immune modulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Bone marrow-derived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Effects of human mesenchymal stem cells on the differentiation of dendritic cells from CD34+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human mesenchymal stem cells license adult CD34+ hemopoietic progenitor cells to differentiate into regulatory dendritic cells through activation of the Notch pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem/stromal cells induce the generation of novel IL-10-dependent regulatory dendritic cells by SOCS3 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human regulatory T cells in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Regulatory immune cells in transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells induce functionally active T-regulatory lymphocytes in a paracrine fashion and ameliorate experimental autoimmune uveitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

TGF-beta expression by allogeneic bone marrow stromal cells ameliorates diabetes in NOD mice through modulating the distribution of CD4+ T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Inflammatory cytokine-induced intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in mesenchymal stem cells are critical for immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

New insights into mesenchymal stromal cell-mediated T-cell suppression through galectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of CX3CL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Human mesenchymal stem cells inhibit antibody production induced in vitro by allostimulation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Proteomic analysis of tumor necrosis factor-alpha-induced secretome of human adipose tissue-derived mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Mesenchymal stromal cells derived from umbilical cord blood migrate in response to complement C1q

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

IFN-γ and TNF-α differentially regulate immunomodulation by murine mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Bone marrow-derived mesenchymal stem cells inhibit acute rejection of rat liver allografts in association with regulatory T-cell expansion

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.56

7 January 2021

Identifiers

DOI

10.1038/ICB.2012.56

1 reference

Dimensions Publication ID

27 August 2017

1036157958

0 references

1 reference