(Q38056038)

1 July 2019

title

EYA1-SIX1 complex in neurosensory cell fate induction in the mammalian inner ear (English)

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1 July 2019

author name string

Elaine Y M Wong

series ordinal

1

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1 July 2019

Mohi Ahmed

series ordinal

2

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1 July 2019

Pin-Xian Xu

series ordinal

3

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1 July 2019

language of work or name

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24 October 2012

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1 July 2019

published in

Hearing Research

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1 July 2019

volume

297

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1 July 2019

page(s)

13-19

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1 July 2019

p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti

cites work

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12 December 2020

Math1: an essential gene for the generation of inner ear hair cells

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12 December 2020

The zebrafish eya1 gene and its expression pattern during embryogenesis

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12 December 2020

Six class homeobox genes in drosophila belong to three distinct families and are involved in head development

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12 December 2020

Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia

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12 December 2020

Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya

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12 December 2020

A conserved blueprint for the eye?

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12 December 2020

Autoregulation and multiple enhancers control Math1 expression in the developing nervous system

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12 December 2020

Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians

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12 December 2020

Six family genes--structure and function as transcription factors and their roles in development

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12 December 2020

The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteins

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12 December 2020

Making sense of making hair cells.

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12 December 2020

Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus

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12 December 2020

The Caenorhabditis elegans Six/sine oculis class homeobox gene ceh-32 is required for head morphogenesis

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12 December 2020

Revisiting cell fate specification in the inner ear.

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12 December 2020

Impaired interactions between mouse Eyal harboring mutations found in patients with branchio-oto-renal syndrome and Six, Dach, and G proteins

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12 December 2020

The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination

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12 December 2020

Tissue-specific regulation of retinal and pituitary precursor cell proliferation

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12 December 2020

A 4-bp insertion in the eya-homologous region (eyaHR) of EYA4 causes hearing impairment in a Hungarian family linked to DFNA10

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12 December 2020

Six1 is required for the early organogenesis of mammalian kidney

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12 December 2020

Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice

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12 December 2020

The role of Six1 in mammalian auditory system development

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12 December 2020

Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.

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12 December 2020

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

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12 December 2020

Eyes absent represents a class of protein tyrosine phosphatases

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12 December 2020

The transcription factor Eyes absent is a protein tyrosine phosphatase

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12 December 2020

Six1 controls patterning of the mouse otic vesicle

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12 December 2020

The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1

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12 December 2020

SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes

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12 December 2020

Expression of zebrafish six1 during sensory organ development and myogenesis.

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12 December 2020

Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family

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12 December 2020

From placode to polarization: new tunes in inner ear development

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12 December 2020

Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes

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12 December 2020

Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor.

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12 December 2020

The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line

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12 December 2020

Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss

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12 December 2020

Sox2 is required for sensory organ development in the mammalian inner ear

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12 December 2020

Evolutionary origins of vertebrate placodes: insights from developmental studies and from comparisons with other deuterostomes

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12 December 2020

Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis

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12 December 2020

The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis.

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12 December 2020

Induction and specification of cranial placodes

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12 December 2020

A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti development.

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12 December 2020

Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear

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12 December 2020

Inducible Cre recombinase activity in mouse cerebellar granule cell precursors and inner ear hair cells.

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12 December 2020

The transcription factor six1 inhibits neuronal and promotes hair cell fate in the developing zebrafish (Danio rerio) inner ear.

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12 December 2020

Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome

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12 December 2020

Evolution of the gene families forming the Pax/Six regulatory network: isolation of genes from primitive animals and molecular phylogenetic analyses

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12 December 2020

Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear.

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12 December 2020

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

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12 December 2020

Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent

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12 December 2020

Regulation of the innate immune response by threonine-phosphatase of Eyes absent

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12 December 2020

EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis

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12 December 2020

Sox2 induces neuronal formation in the developing mammalian cochlea

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12 December 2020

The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cells

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12 December 2020

Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development

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12 December 2020

Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2.

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12 December 2020

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

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12 December 2020

Development of the inner ear of the mouse: a radioautographic study of terminal mitoses

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12 December 2020

Homeobox genes and connective tissue patterning

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12 December 2020

sine oculis is a homeobox gene required for Drosophila visual system development

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12 December 2020

The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system

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12 December 2020

The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

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12 December 2020

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.

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12 December 2020

Structure, function and expression of a murine homeobox protein AREC3, a homologue of Drosophila sine oculis gene product, and implication in development

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12 December 2020

Identification and expression of six family genes in mouse retina

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12 December 2020

Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode

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12 December 2020

A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family

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12 December 2020

Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene

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12 December 2020

Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function

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12 December 2020

Clustering of mutations responsible for branchio-oto-renal (BOR) syndrome in the eyes absent homologous region (eyaHR) of EYA1

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12 December 2020

The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development

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12 December 2020

Development of the mouse inner ear and origin of its sensory organs.

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12 December 2020

Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis

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12 December 2020

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

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12 December 2020

EYA4, a novel vertebrate gene related to Drosophila eyes absent

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12 December 2020

10.1016/J.HEARES.2012.09.009

Identifiers

DOI

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1 July 2019

PMC publication ID

6592049

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1 July 2019

PubMed publication ID

23104013

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1 July 2019