(Q38059391)

28 August 2017

The ASXL-BAP1 axis: new factors in myelopoiesis, cancer and epigenetics (English)

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28 August 2017

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1

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28 August 2017

A Dey

2

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28 August 2017

9 October 2012

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28 August 2017

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28 August 2017

27

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28 August 2017

1

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28 August 2017

10-15

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https://scigraph.springernature.com/pub.10.1038/leu.2012.288

28 August 2017

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cites work

Loss of the tumor suppressor BAP1 causes myeloid transformation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Defining the human deubiquitinating enzyme interaction landscape

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Clinical effect of point mutations in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Frequent mutation of BAP1 in metastasizing uveal melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Germline BAP1 mutations predispose to malignant mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Germline mutations in BAP1 predispose to melanocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

BAP1 loss defines a new class of renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

The mutational landscape of lethal castration-resistant prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

An emerging model for BAP1's role in regulating cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Host cell factor-1 and E2F4 interact via multiple determinants in each protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Functional conservation of Asxl2, a murine homolog for the Drosophila enhancer of trithorax and polycomb group gene Asx

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Mutations of ASXL1 gene in myeloproliferative neoplasms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

EZH2 mutational status predicts poor survival in myelofibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

The consensus coding sequences of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

inferred from DOI database lookup

7 January 2021

based on heuristic

Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.288

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2012.288

1 reference

PubMed ID

23147254

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23147254