(Q38059468)

28 August 2017

title

Disease modelling using induced pluripotent stem cells: status and prospects (English)

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28 August 2017

Oz Pomp

1

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28 August 2017

Alan Colman

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

13 November 2012

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28 August 2017

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28 August 2017

volume

35

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28 August 2017

issue

3

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28 August 2017

page(s)

271-280

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Embryonic stem cell lines derived from human blastocysts

28 August 2017

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iPS cells can support full-term development of tetraploid blastocyst-complemented embryos

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iPS cells produce viable mice through tetraploid complementation

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Human pluripotent stem cells in drug discovery and predictive toxicology

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Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells

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Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

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Two factor reprogramming of human neural stem cells into pluripotency

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Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells

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Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2.

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Environmental pollutants and skin cancer

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Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells

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Reprogramming efficiency and quality of induced Pluripotent Stem Cells (iPSCs) generated from muscle-derived fibroblasts of mdx mice at different ages

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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

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Virus-free induction of pluripotency and subsequent excision of reprogramming factors

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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

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Reprogramming of mouse and human cells to pluripotency using mature microRNAs.

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

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The promise of induced pluripotent stem cells in research and therapy

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

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Somatic coding mutations in human induced pluripotent stem cells

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Copy number variation and selection during reprogramming to pluripotency

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Disease-specific induced pluripotent stem cells

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

21 January 2018

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Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

21 January 2018

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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

21 January 2018

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Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells

21 January 2018

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

21 January 2018

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Dissecting direct reprogramming through integrative genomic analysis

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Epigenetic memory in induced pluripotent stem cells

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Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation

21 January 2018

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Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.

21 January 2018

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Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation

21 January 2018

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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

21 January 2018

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Derivation of pluripotent epiblast stem cells from mammalian embryos

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New cell lines from mouse epiblast share defining features with human embryonic stem cells

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

21 January 2018

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X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

21 January 2018

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Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions

21 January 2018

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Erosion of dosage compensation impacts human iPSC disease modeling

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Unexpected X chromosome skewing during culture and reprogramming of human somatic cells can be alleviated by exogenous telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Female human iPSCs retain an inactive X chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Metastable pluripotent states in NOD-mouse-derived ESCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Harnessing the potential of induced pluripotent stem cells for regenerative medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Advances in the understanding of dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

A functionally characterized test set of human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200088

Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Modeling oculopharyngeal muscular dystrophy in myotube cultures reveals reduced accumulation of soluble mutant PABPN1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

MeCP2, a key contributor to neurological disease, activates and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Modelling schizophrenia using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Constructing and deconstructing stem cell models of neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Comparative analysis of human embryonic stem cell and induced pluripotent stem cell-derived hepatocyte-like cells reveals current drawbacks and possible strategies for improved differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

New approaches in the therapy of cardiomyopathy in muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

The ground state of embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

The dark side of induced pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200088

21 January 2018

Identifiers

DOI

10.1002/BIES.201200088

1 reference

28 August 2017

1 reference