(Q38060419)

28 August 2017

The Ca-calmodulin dependent kinase II: a promising target for future antiarrhythmic therapies? (English)

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Collaborative Research Centre (CRC) 1002: "Modulatory Units in Heart Failure"

28 August 2017

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author name string

Thomas H Fischer

series ordinal

1

1 reference

PubMed ID

23159442

28 August 2017

Stefan Neef

series ordinal

2

1 reference

PubMed ID

23159442

28 August 2017

Lars S Maier

series ordinal

3

1 reference

28 August 2017

13 November 2012

1 reference

Journal of Molecular and Cellular Cardiology

28 August 2017

1 reference

28 August 2017

58

1 reference

28 August 2017

182-187

1 reference

Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).

28 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Sudden unexpected death in patients with congestive heart failure: a second frontier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Prevalence of left-ventricular systolic dysfunction and heart failure in the Echocardiographic Heart of England Screening study: a population based study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

The prognosis of heart failure in the general population: The Rotterdam Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Evidence of improving prognosis in heart failure: trends in case fatality in 66 547 patients hospitalized between 1986 and 1995

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Survival of patients with a new diagnosis of heart failure: a population based study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Intermittent, ambulatory dobutamine infusions in patients with severe congestive heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Interaction of ischaemia and encainide/flecainide treatment: a proposed mechanism for the increased mortality in CAST I

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

New therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

CaMKII regulation of phospholamban and SR Ca2+ load

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calmodulin kinase II is required for fight or flight sinoatrial node physiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Phospholamban is required for CaMKII-dependent recovery of Ca transients and SR Ca reuptake during acidosis in cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Effects on recovery during acidosis in cardiac myocytes overexpressing CaMKII.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calmodulin trapping by calcium-calmodulin-dependent protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Alterations of calcium-regulatory proteins in heart failure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Differential cardiac remodeling in preload versus afterload

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calcium release from the sarcoplasmic reticulum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Cardiac excitation-contraction coupling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Overexpression of CaMKIIδc in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Structure and regulation of voltage-gated Ca2+ channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Orphaned ryanodine receptors in the failing heart.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Pathophysiologic mechanisms of cardiac arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

A calcium sensor in the sodium channel modulates cardiac excitability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

A single Na(+) channel mutation causing both long-QT and Brugada syndromes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Diagnosis and management of Brugada Syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδ(C) can be reversed by inhibition of late Na(+) current

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events: implications for mutation-specific response to β-blocker therapy in type 1 long-QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Ca/calmodulin kinase II differentially modulates potassium currents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Differential inhibition of hjkhj transient outward currents of Kv1.4 and Kv4.3 by endothelin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Calmodulin kinase II inhibition shortens action potential duration by upregulation of K+ currents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.11.003

10.1016/J.YJMCC.2012.11.003

7 January 2021

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23159442