(Q38060941)

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Multiple effects of physical activity on molecular and cognitive signs of brain aging: can exercise slow neurodegeneration and delay Alzheimer's disease?

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23164816%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

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Europe PubMed Central

Multiple effects of physical activity on molecular and cognitive signs of brain aging: can exercise slow neurodegeneration and delay Alzheimer's disease? (English)

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Europe PubMed Central

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18 February 2020

Alzheimer's disease

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neurodegeneration

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based on heuristic

inferred from title

Jeremiah J. Peiffer

2

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18 February 2020

3

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18 February 2020

author name string

B M Brown

1

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18 February 2020

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20 November 2012

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18 February 2020

Molecular Psychiatry

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18 February 2020

18

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18 February 2020

8

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18 February 2020

864-874

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18 February 2020

https://scigraph.springernature.com/pub.10.1038/mp.2012.162

0 references

Physical activity and the incidence of coronary heart disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Ph

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Changes in cognition and mortality in relation to exercise in late life: a population based study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Cognition in older women: the importance of daytime movement

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

A prospective study of physical activity and cognitive decline in elderly women: women who walk

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity and risk of cognitive impairment and dementia in elderly persons

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Replication of age and physical activity effects on reaction and movement time

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity, including walking, and cognitive function in older women.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Improvement of cognitive function by mental and/or individualized aerobic training in healthy elderly subjects.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Intensity, but not duration, of physical activities is related to cognitive function.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical exercise, aging, and mild cognitive impairment: a population-based study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Limits to the measurement of habitual physical activity by questionnaires

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Activity energy expenditure and incident cognitive impairment in older adults

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity, diet, and risk of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Total daily physical activity and the risk of AD and cognitive decline in older adults.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Participation in cognitively stimulating activities and risk of incident Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Effects of aerobic exercise on mild cognitive impairment: a controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Changes in cognitive function in a randomized trial of physical activity: results of the lifestyle interventions and independence for elders pilot study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Ageing, fitness and neurocognitive function.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

The Impact of Resistance Exercise on the Cognitive Function of the Elderly

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Resistance training and executive functions: a 12-month randomized controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Fitness effects on the cognitive function of older adults: a meta-analytic study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Resistance training and functional plasticity of the aging brain: a 12-month randomized controlled trial.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Resistance training promotes cognitive and functional brain plasticity in seniors with probable mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity and functional limitations in older adults: a systematic review related to Canada's Physical Activity Guidelines

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity and risk of cognitive decline: a meta-analysis of prospective studies

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise physiologists talk about sex differences

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity in relation to cognitive decline in elderly men: the FINE Study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Walking and dementia in physically capable elderly men.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

A 3-year follow-up study of social, lifestyle and health predictors of cognitive impairment in a Chinese older cohort.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Protective actions of sex steroid hormones in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise and Alzheimer's disease biomarkers in cognitively normal older adults

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise moderates age-related atrophy of the medial temporal lobe

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Aerobic fitness reduces brain tissue loss in aging humans.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Aerobic fitness is associated with hippocampal volume in elderly humans

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Aerobic exercise training increases brain volume in aging humans.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Cardiorespiratory fitness and preserved medial temporal lobe volume in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise training increases size of hippocampus and improves memory

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

The adaptive brain: aging and neurocognitive scaffolding

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Cardiovascular fitness modulates brain activation associated with spatial learning.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Beyond vascularization: aerobic fitness is associated with N-acetylaspartate and working memory

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

High impact running improves learning.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Social and leisure activities and risk of dementia: a prospective longitudinal study.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Evidence for a release of brain-derived neurotrophic factor from the brain during exercise.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Sedentary life impairs self-reparative processes in the brain: the role of serum insulin-like growth factor-I.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Serum growth factors and neuroprotective surveillance: focus on IGF-1.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Insulin-like growth factor-I enhances the biological activity of brain-derived neurotrophic factor on cerebrocortical neurons.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Dopamine modulates cholinergic cortical excitability in Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Regulation of brain function by exercise

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Striatal dopamine turnover during treadmill running in the rat: relation to the speed of running.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Moderate exercise and chronic stress produce counteractive effects on different areas of the brain by acting through various neurotransmitter receptor subtypes: a hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Running enhances neurogenesis, learning, and long-term potentiation in mice

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Mechanisms of stroke protection by physical activity.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity of moderate intensity and risk of type 2 diabetes: a systematic review

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Physical activity and insulin sensitivity: the RISC study

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Sedentary behavior, physical activity, and concentrations of insulin among US adults

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Age-associated chronic diseases require age-old medicine: role of chronic inflammation

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Association of leisure-time physical activity with cognition by apolipoprotein-E genotype in persons aged 60 years and over: the National Health and Nutrition Examination Survey (NHANES-III)

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Perceived exertion of physical activity: Negative association with self-rated fitness

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Exercise and brain neurotrophins

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

21 January 2018

Cognitive activity and incident AD in a population-based sample of older persons

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Physical activity and cognitive decline, the role of the apolipoprotein e4 allele

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical localization of N-acetylaspartate in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Letter to the Editor: Standardized use of the terms “sedentary” and “sedentary behaviours”

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.162

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/MP.2012.162

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23164816%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23164816%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

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