(Q38062476)

28 August 2017

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title

The central theme of Parkinson's disease: α-synuclein (English)

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28 August 2017

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Mehmet Ozansoy

1

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28 August 2017

A Nazli Başak

series ordinal

2

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28 August 2017

publication date

23 November 2012

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28 August 2017

published in

Molecular Neurobiology

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28 August 2017

volume

47

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28 August 2017

issue

2

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28 August 2017

page(s)

460-465

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https://scigraph.springernature.com/pub.10.1007/s12035-012-8369-3

28 August 2017

exact match

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cites work

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

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alpha-Synuclein locus triplication causes Parkinson's disease

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Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication.

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Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms

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α-Synuclein and dopamine at the crossroads of Parkinson's disease

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

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Inhibition of tyrosine hydroxylase expression in alpha-synuclein-transfected dopaminergic neuronal cells

21 January 2018

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

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Alpha-synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells

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Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

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Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

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Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

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Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

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α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

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Identifying PD-causing genes and genetic susceptibility factors: current approaches and future prospects

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12 December 2020

Ubiquitination of alpha-synuclein by Siah-1 promotes alpha-synuclein aggregation and apoptotic cell death.

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12 December 2020

Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines

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Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

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12 December 2020

Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation

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12 December 2020

10.1007/S12035-012-8369-3

Identifiers

DOI

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Dimensions Publication ID

28 August 2017

1012508788

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