(Q38082796)

28 August 2017

title

Transient receptor potential vanilloid 1 as a therapeutic target in analgesia (English)

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28 August 2017

János Szolcsányi

1

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28 August 2017

Erika Pintér

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

20 February 2013

1 reference

Expert Opinion on Therapeutic Targets

28 August 2017

published in

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28 August 2017

volume

17

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28 August 2017

issue

6

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28 August 2017

page(s)

641-657

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Forty years in capsaicin research for sensory pharmacology and physiology

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Sensory neuron-specific actions of capsaicin: mechanisms and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The capsaicin receptor: a heat-activated ion channel in the pain pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The cloned capsaicin receptor integrates multiple pain-producing stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Transient receptor potential vanilloid-1 antagonists: a survey of recent patent literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

A multicenter, randomized, double-blind, controlled study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

NGX-4010, a capsaicin 8% dermal patch, administered alone or in combination with systemic neuropathic pain medications, reduces pain in patients with postherpetic neuralgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Separate peripheral pathways for pruritus in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Inhibition of the function of TRPV1-expressing nociceptive sensory neurons by somatostatin 4 receptor agonism: mechanism and therapeutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The history of TRP channels, a commentary and reflection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Structure of TRPV1 channel revealed by electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Identification of a tetrameric assembly domain in the C terminus of heat-activated TRPV1 channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Nociception, neurogenic inflammation and thermoregulation in TRPV1 knockdown transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Regulation of nociceptive transmission at the periphery via TRPA1-TRPV1 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

TRPV1 and TRPA1 function and modulation are target tissue dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The transient receptor potential family of ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Multisteric TRPV1 nocisensor: a target for analgesics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

TRPV1 acts as proton channel to induce acidification in nociceptive neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

TRPV1 shows dynamic ionic selectivity during agonist stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Tunable calcium current through TRPV1 receptor channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The dilated TRPA1 channel pore state is blocked by amiloride and analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Activation of transient receptor potential vanilloid 1 (TRPV1) by resiniferatoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Versatile regulation of cytosolic Ca2+ by vanilloid receptor I in rat dorsal root ganglion neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The influence of removing extracellular Ca2+ in the desensitization responses to capsaicin, zingerone and olvanil in rat trigeminal ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Nociceptor structural specialization in canine and rodent testicular "free" nerve endings

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Inflammatory pain: the cellular basis of heat hyperalgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Receptor-targeting mechanisms of pain-causing toxins: How ow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Modulation of single-channel properties of TRPV1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Phosphorylation of vanilloid receptor 1 by Ca2+/calmodulin-dependent kinase II regulates its vanilloid binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Relative roles of protein kinase A and protein kinase C in modulation of transient receptor potential vanilloid type 1 receptor responsiveness in rat sensory neurons in vitro and peripheral nociceptors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

NGF and GDNF differentially regulate TRPV1 expression that contributes to development of inflammatory thermal hyperalgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Comparison of P2X and TRPV1 receptors in ganglia or primary culture of trigeminal neurons and their modulation by NGF or serotonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Thermal nociception and TRPV1 function are attenuated in mice lacking the nucleotide receptor P2Y2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

A "cute" desensitization of TRPV1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Antinociceptive desensitizing actions of TRPV1 receptor agonists capsaicin, resiniferatoxin and N-oleoyldopamine as measured by determination of the noxious heat and cold thresholds in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Neonatal capsaicin treatment results in prolonged mitochondrial damage and delayed cell death of B cells in the rat trigeminal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Neonatal anandamide treatment results in prolonged mitochondrial damage in the vanilloid receptor type 1-immunoreactive B-type neurons of the rat trigeminal ganglion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The receptive part of the primary afferent axon is most vulnerable to systemic capsaicin in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Correlation of mitochondrial swelling after capsaicin treatment and substance P and somatostatin immunoreactivity in small neurons of dorsal root ganglion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

TRPV1-lineage neurons are required for thermal sensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Effect of transient receptor potential vanilloid 1 (TRPV1) receptor antagonist compounds SB705498, BCTC and AMG9810 in rat models of thermal hyperalgesia measured with an increasing-temperature water bath.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Human keratinocytes are vanilloid resistant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Unravelling the mystery of capsaicin: a tool to understand and treat pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Transient receptor potential channels as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Capsaicin and central control of thermoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Transient receptor potential ion channels as participants in thermosensation and thermoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Capsaicin 8% topical patch (Qutenza)--a review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Essential role of mitochondrial permeability transition in vanilloid receptor 1-dependent cell death of sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Intranasal civamide for the treatment of episodic cluster headaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Acute and preventive pharmacologic treatment of cluster headache

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Betulin is a potent anti-tumor agent that is enhanced by cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Therapeutic targeting of TRPV1 by resiniferatoxin, from preclinical studies to clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

The vanilloid agonist resiniferatoxin for interventional-based pain control

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.772580

10.1517/14728222.2013.772580

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference