(Q38086137)

28 August 2017

title

Targeting interleukin-6 in rheumatoid arthritis (English)

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28 August 2017

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2

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28 August 2017

Md Yuzaiful Md Yusof

1

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28 August 2017

publication date

1 March 2013

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full work available at URL

28 August 2017

http://eprints.whiterose.ac.uk/85075/

content deliverer

White Rose Research Online

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published in

Drugs

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28 August 2017

volume

73

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28 August 2017

issue

4

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28 August 2017

page(s)

341-356

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The epidemiology of rheumatoid arthritis

28 August 2017

cites work

1 reference

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21 January 2018

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IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

21 January 2018

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21 January 2018

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Molecular cloning and expression of an IL-6 signal transducer, gp130

21 January 2018

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Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

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Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family

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The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells

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The roles of interleukin-6 in the pathogenesis of rheumatoid arthritis

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

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Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

21 January 2018

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IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae

21 January 2018

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21 January 2018

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Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation

21 January 2018

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Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor

21 January 2018

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Tocilizumab - a novel therapy for non-organ-specific autoimmune diseases

21 January 2018

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21 January 2018

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Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman's disease

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The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.

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Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial

21 January 2018

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Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study

21 January 2018

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Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

21 January 2018

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Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study.

21 January 2018

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Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score

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Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

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Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

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21 January 2018

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21 January 2018

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Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials

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Total cholesterol and LDL levels decrease before rheumatoid arthritis

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Interleukin-6 stimulates lipolysis and fat oxidation in humans

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21 January 2018

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21 January 2018

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

"Arthritis specific" global health analog scales assess "generic" health related quality-of-life in patients with rheumatoid arthritis.

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12 December 2020

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12 December 2020

A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis

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12 December 2020

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12 December 2020

Complete remission of myeloperoxidase-anti-neutrophil cytoplasmic antibody-associated crescentic glomerulonephritis complicated with rheumatoid arthritis using a humanized anti-interleukin 6 receptor antibody

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Interleukin-6 receptor inhibition with tocilizumab and attainment of disease remission in rheumatoid arthritis: the role of acute-phase reactants

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12 December 2020

Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis

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12 December 2020

Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate

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12 December 2020

Interleukin-6 in synovial fluid is closely associated with chronic synovitis in rheumatoid arthritis

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12 December 2020

Interleukin-6 induces demargination of intravascular neutrophils and shortens their transit in marrow

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12 December 2020

Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of s

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

10.1007/S40265-013-0018-2

Identifiers

DOI

1 reference

10.1007/S40265-013-0018-2

28 August 2017

Altmetric DOI

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Dimensions Publication ID

1008400750

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Fatcat ID

release_sedlektwh5fs7bwvr22m2tblxy

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Fatcat

https://api.fatcat.wiki/v0/release/sedlektwh5fs7bwvr22m2tblxy

24 November 2022

mapped directly with Wikidata item

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