(Q38089206)

28 August 2017

Preclinical development of cancer stem cell drugs (English)

1 reference

28 August 2017

neoplastic stem cells

1 reference

Jiangbing Zhou

1

1 reference

PubMed ID

23489167

28 August 2017

Ying Zhang

series ordinal

2

1 reference

PubMed ID

23489167

28 August 2017

language of work or name

English

0 references

publication date

9 June 2009

1 reference

Expert Opinion on Drug Discovery

28 August 2017

1 reference

28 August 2017

4

1 reference

28 August 2017

741-752

1 reference

28 August 2017

7

1 reference

Stem cells, cancer, and cancer stem cells

28 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Cancer stem cells: Models, mechanisms and implications for improved treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Cancer stem cells: models and concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

"Destemming" cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Characterization of clonogenic multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Phenotypic characterization of human colorectal cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A tumorigenic subpopulation with stem cell properties in melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification and expansion of the tumorigenic lung cancer stem cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification of cells initiating human melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Epigenetic stem cell signature in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Therapeutic implications of cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Will cancer stem cells provide new therapeutic targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

21 January 2018

Liver cancer stem cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Chemotherapy resistance of glioblastoma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Characterization of a side population of cancer cells from human gastrointestinal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The prognostic role of a gene signature from tumorigenic breast-cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The CD44+/CD24- phenotype is enriched in basal-like breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The role of ABC transporters in drug resistance, metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(+)CD38(-) progenitor cells from patients with acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Characterization of side population in thyroid cancer cell lines: cancer stem-like cells are enriched partly but not exclusively.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Strengths and limitations of the neurosphere culture system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Chemical genetics reveals a complex functional ground state of neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Targeted therapy for cancer stem cells: the patched pathway and ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Mechanisms controlling pathogenesis and survival of leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

let-7 regulates self renewal and tumorigenicity of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The properties of a mammary gland cancer stem cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Stem cell niche: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

A perivascular niche for brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

The paradox of response and survival in cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Detection and characterization of CD133+ cancer stem cells in human solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

Temozolomide preferentially depletes cancer stem cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440903002059

10.1517/17460440903002059

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23489167