(Q38091729)

28 August 2017

title

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease (English)

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28 August 2017

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Donna K Finch

1

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28 August 2017

Rachel Ettinger

2

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28 August 2017

Jodi L Karnell

3

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28 August 2017

Ronald Herbst

4

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28 August 2017

Matthew A Sleeman

5

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28 August 2017

publication date

20 March 2013

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European Journal of Clinical Investigation

28 August 2017

published in

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28 August 2017

volume

43

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28 August 2017

issue

5

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28 August 2017

page(s)

501-509

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A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1

28 August 2017

cites work

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B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5

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Follicular stromal cells and lymphocyte homing to follicles.

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A chemokine-driven positive feedback loop organizes lymphoid follicles

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A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

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Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

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CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

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CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity

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BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

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Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium

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CXCL13: a novel biomarker of B-cell return following rituximab treatment and synovitis in patients with rheumatoid arthritis

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21 January 2018

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Cracking the BAFF code.

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In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice

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21 January 2018

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In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines

21 January 2018

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T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

21 January 2018

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Unique gene expression program of human germinal center T helper cells

21 January 2018

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CXCL13 blockade disrupts B lymphocyte organization in tertiary lymphoid structures without altering B cell receptor bias or preventing diabetes in nonobese diabetic mice

21 January 2018

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Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice

21 January 2018

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Cutting edge: ectopic expression of the chemokine TCA4/SLC is sufficient to trigger lymphoid neogenesis.

21 January 2018

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Ectopic LTαβ Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted Sulfotransferase

21 January 2018

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21 January 2018

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B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectives

21 January 2018

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A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus

21 January 2018

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Treatment of systemic lupus erythematosus with epratuzumab.

21 January 2018

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Epratuzumab targeting of CD22 affects adhesion molecule expression and migration of B-cells in systemic lupus erythematosus.

21 January 2018

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Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis.

21 January 2018

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B cell follicles and antigen encounters of the third kind

21 January 2018

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

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Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.

21 January 2018

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Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

21 January 2018

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Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment

21 January 2018

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B cells undergo unique compartmentalized redistribution in multiple sclerosis

21 January 2018

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21 January 2018

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Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus

21 January 2018

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Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5

21 January 2018

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Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome

21 January 2018

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Chemokines determine local lymphoneogenesis and a reduction of circulating CXCR4+ T and CCR7 B and T lymphocytes in thyroid autoimmune diseases.

21 January 2018

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The role of CXCR5 and its ligand CXCL13 in the compartmentalization of lymphocytes in thyroids affected by autoimmune thyroid diseases

21 January 2018

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The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis

21 January 2018

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Identification of CXCL13 as a marker for rheumatoid arthritis outcome using an in silico model of the rheumatic joint

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/ECI.12063

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28 August 2017

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