(Q38098875)

28 August 2017

title

The ageing haematopoietic stem cell compartment (English)

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28 August 2017

Hartmut Geiger

1

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28 August 2017

Gerald de Haan

series ordinal

2

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28 August 2017

M Carolina Florian

series ordinal

3

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28 August 2017

publication date

15 April 2013

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Nature Reviews Immunology

28 August 2017

published in

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28 August 2017

volume

13

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28 August 2017

issue

5

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28 August 2017

page(s)

376-389

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Stems cells and the pathways to aging and cancer

28 August 2017

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Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

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Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

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Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence.

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Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.

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31 March 2020

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31 March 2020

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31 March 2020

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Immortal strands? Give me a break

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

31 March 2020

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De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

31 March 2020

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Dnmt3a is essential for hematopoietic stem cell differentiation

31 March 2020

1 reference

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

31 March 2020

1 reference

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells.

31 March 2020

1 reference

Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression

31 March 2020

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Epigenetic regulation of aging stem cells

31 March 2020

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Centrosome misorientation reduces stem cell division during ageing

31 March 2020

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Gene expression profiles associated with aging and mortality in humans

31 March 2020

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Concise review: polarity in stem cells, disease, and aging.

31 March 2020

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31 March 2020

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31 March 2020

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Osteoblastic cells regulate the haematopoietic stem cell niche

31 March 2020

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Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

31 March 2020

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Identification of the haematopoietic stem cell niche and control of the niche size

31 March 2020

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Aging of marrow stromal (skeletal) stem cells and their contribution to age-related bone loss

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

1 reference

Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors.

31 March 2020

1 reference

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells

31 March 2020

1 reference

Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

mTOR-what does it do?

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31 March 2020

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Cdc42--the centre of polarity

31 March 2020

1 reference

Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes

31 March 2020

1 reference

Rapamycin slows aging in mice

31 March 2020

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Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

31 March 2020

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

31 March 2020

1 reference

Extension of chronological life span in yeast by decreased TOR pathway signaling

31 March 2020

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Role of TOR signaling in aging and related biological processes in Drosophila melanogaster

31 March 2020

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

31 March 2020

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Manifestations and mechanisms of stem cell aging.

31 March 2020

1 reference

Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

31 March 2020

1 reference

Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy.

31 March 2020

1 reference

The stem cell niche: tissue physiology at a single cell level

31 March 2020

1 reference

The hematopoietic stem cell niche.

31 March 2020

1 reference

Intercellular transfer to signalling endosomes regulates an ex vivo bone marrow niche

31 March 2020

1 reference

Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche

31 March 2020

1 reference

Bone, microenvironment and hematopoiesis

31 March 2020

1 reference

Stability and flexibility of epigenetic gene regulation in mammalian development

31 March 2020

1 reference

Human DNA methylomes at base resolution show widespread epigenomic differences

31 March 2020

1 reference

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

31 March 2020

1 reference

Hot topics in epigenetic mechanisms of aging: 2011.

31 March 2020

1 reference

Epigenetic modifications: basic mechanisms and role in cardiovascular disease.

31 March 2020

1 reference

The great unravelling: chromatin as a modulator of the aging process

31 March 2020

1 reference

DNA damage, chromatin, and transcription: the trinity of aging

31 March 2020

1 reference

Purification and characterization of mouse hematopoietic stem cells

31 March 2020

1 reference

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

31 March 2020

1 reference

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

31 March 2020

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Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells

31 March 2020

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Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

31 March 2020

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

31 March 2020

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Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

31 March 2020

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Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development.

31 March 2020

1 reference

Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment.

31 March 2020

1 reference

Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations.

31 March 2020

1 reference

12 December 2020

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

1 reference

12 December 2020

Cdc42: a signal coordinator in hematopoietic stem cell maintenance

1 reference

12 December 2020

Quantitation of murine and human hematopoietic stem cells by limiting-dilution analysis in competitively repopulated hosts

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12 December 2020

Connexin-43 gap junctions are involved in multiconnexin-expressing stromal support of hemopoietic progenitors and stem cells

1 reference

12 December 2020

Deterministic regulation of hematopoietic stem cell self-renewal and differentiation.

1 reference

12 December 2020

Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity.

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12 December 2020

The hematopoietic stem cell niche

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NRI3433

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28 August 2017

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