(Q38104684)

28 August 2017

Recent advances in the study of enzyme promiscuity in the tautomerase superfamily (English)

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28 August 2017

Bert-Jan Baas

1

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28 August 2017

Ellen Zandvoort

series ordinal

2

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28 August 2017

Edzard M Geertsema

series ordinal

3

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28 August 2017

Gerrit J Poelarends

series ordinal

4

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28 August 2017

3 May 2013

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28 August 2017

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28 August 2017

14

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28 August 2017

917-926

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28 August 2017

8

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What makes an enzyme promiscuous?

28 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Role of chemistry versus substrate binding in recruiting promiscuous enzyme functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Evolution of Enzymatic Activities in the Enolase Superfamily: Stereochemically Distinct Mechanisms in Two Families of cis , cis -Muconate Lactonizing Enzymes † ‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Enhancing catalytic promiscuity for biocatalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Catalytic promiscuity in biocatalysis: using old enzymes to form new bonds and follow new pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Enzyme promiscuity: a mechanistic and evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the alpha-protons of carboxylic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The chemical versatility of the beta-alpha-beta fold: catalytic promiscuity and divergent evolution in the tautomerase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Enzyme recruitment in evolution of new function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

21 January 2018

Evolution and tinkering

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Catalytic promiscuity and the evolution of new enzymatic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Evolution of enzyme superfamilies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The hydratase activity of malonate semialdehyde decarboxylase: mechanistic and evolutionary implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Enzyme promiscuity: mechanism and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Enzymes with extra talents: moonlighting functions and catalytic promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Structural classification of proteins: new superfamilies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Mechanistic characterization of a bacterial malonate semialdehyde decarboxylase: identification of a new activity on the tautomerase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural studies of the 1,3-dichloropropene catabolic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Bacterial metabolism of 3-chloroacrylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Structural and mechanistic analysis oftrans-3-chloroacrylic acid dehalogenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

A persistent pesticide residue and the unusual catalytic proficiency of a dehalogenating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

trans-3-Chloroacrylic acid dehalogenase from Pseudomonas pavonaceae 170 shares structural and mechanistic similarities with 4-oxalocrotonate tautomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The 4-oxalocrotonate tautomerase- and YwhB-catalyzed hydration of 3E-haloacrylates: implications for the evolution of new enzymatic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Characterization of a newly identified mycobacterial tautomerase with promiscuous dehalogenase and hydratase activities reveals a functional link to a recently diverged cis-3-chloroacrylic acid dehalogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Adaptation of Corynebacterium glutamicum to ammonium limitation: a global analysis using transcriptome and proteome techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Inactivation of 4-oxalocrotonate tautomerase by 2-oxo-3-pentynoate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Reactions of trans-3-chloroacrylic acid dehalogenase with acetylene substrates: consequences of and evidence for a hydration reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

Asymmetric enamine catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The first direct and enantioselective cross-aldol reaction of aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300098

21 January 2018

Identifiers

DOI

10.1002/CBIC.201300098

1 reference

28 August 2017

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