(Q38117742)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23809134%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Insights into thrombin activatable fibrinolysis inhibitor function and regulation (English)

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4 March 2020

3

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4 March 2020

author name string

J H Foley

series ordinal

1

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4 March 2020

P Y Kim

series ordinal

2

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4 March 2020

A Gils

series ordinal

4

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4 March 2020

publication date

1 June 2013

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Journal of Thrombosis and Haemostasis

4 March 2020

published in

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4 March 2020

volume

11 Suppl 1

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4 March 2020

page(s)

306-315

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An arginine specific carboxypeptidase generated in blood during coagulation or inflammation which is unrelated to carboxypeptidase N or its subunits

4 March 2020

cites work

1 reference

Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor

21 January 2018

1 reference

The gene for human carboxypeptidase U (CPU)--a proposed novel regulator of plasminogen activation--maps to 13q14.11.

21 January 2018

1 reference

Characterization of the gene encoding human TAFI (thrombin-activable fibrinolysis inhibitor; plasma procarboxypeptidase B).

21 January 2018

1 reference

Secretion and antifibrinolytic function of thrombin-activatable fibrinolysis inhibitor from human platelets

21 January 2018

1 reference

Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation

21 January 2018

1 reference

Development of a genotype 325-specific proCPU/TAFI ELISA.

21 January 2018

1 reference

Curiouser and curiouser: recent advances in measurement of thrombin-activatable fibrinolysis inhibitor (TAFI) and in understanding its molecular genetics, gene regulation, and biological roles

21 January 2018

1 reference

Post-translational modifications of human thrombin-activatable fibrinolysis inhibitor (TAFI): evidence for a large shift in the isoelectric point and reduced solubility upon activation

21 January 2018

1 reference

Thrombin-activable fibrinolysis inhibitor zymogen does not play a significant role in the attenuation of fibrinolysis

21 January 2018

1 reference

TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex

21 January 2018

1 reference

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

21 January 2018

1 reference

Kinetics of activated thrombin-activatable fibrinolysis inhibitor (TAFIa)-catalyzed cleavage of C-terminal lysine residues of fibrin degradation products and removal of plasminogen-binding sites

21 January 2018

1 reference

Plasmin-mediated activation and inactivation of thrombin-activatable fibrinolysis inhibitor.

21 January 2018

1 reference

Plasmin and the thrombin-thrombomodulin complex both contribute to thrombin-activatable fibrinolysis inhibitor activation in whole blood model thrombi.

21 January 2018

1 reference

Two naturally occurring variants of TAFI (Thr-325 and Ile-325) differ substantially with respect to thermal stability and antifibrinolytic activity of the enzyme.

21 January 2018

1 reference

Generation of a stable activated thrombin activable fibrinolysis inhibitor variant

21 January 2018

1 reference

Characterization of rat thrombin-activatable fibrinolysis inhibitor (TAFI)--a comparative study assessing the biological equivalence of rat, murine and human TAFI

21 January 2018

1 reference

Measurement of procarboxypeptidase U (TAFI) in human plasma: a laboratory challenge

21 January 2018

1 reference

Measurement of carboxypeptidase U (active thrombin-activatable fibrinolysis inhibitor) in plasma: Challenges overcome by a novel selective assay

21 January 2018

1 reference

The role of thrombin activatable fibrinolysis inhibitor and factor XI in platelet-mediated fibrinolysis resistance: a thromboelastographic study in whole blood

21 January 2018

1 reference

An assay for measuring functional activated thrombin-activatable fibrinolysis inhibitor in plasma

21 January 2018

1 reference

Carboxypeptidase U (TAFIa): a new drug target for fibrinolytic therapy?

21 January 2018

1 reference

Plasma carboxypeptidases as regulators of the plasminogen system

21 January 2018

1 reference

A carboxypeptidase inhibitor from the medical leech Hirudo medicinalis. Isolation, sequence analysis, cDNA cloning, recombinant expression, and characterization

21 January 2018

1 reference

A carboxypeptidase inhibitor from the tick Rhipicephalus bursa: isolation, cDNA cloning, recombinant expression, and characterization

21 January 2018

1 reference

Reversible inhibitors of TAFIa can both promote and inhibit fibrinolysis

21 January 2018

1 reference

TAFIa inhibiting nanobodies as profibrinolytic tools and discovery of a new TAFIa conformation.

21 January 2018

1 reference

Stabilization versus inhibition of TAFIa by competitive inhibitors in vitro

21 January 2018

1 reference

Generation and characterization of inhibitory nanobodies towards thrombin activatable fibrinolysis inhibitor

21 January 2018

1 reference

Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon

21 January 2018

1 reference

An inhibitor of activated thrombin-activatable fibrinolysis inhibitor potentiates tissue-type plasminogen activator-induced thrombolysis in a rabbit jugular vein thrombolysis model

21 January 2018

1 reference

Carboxypeptidase B inhibitors reduce tissue factor-induced renal microthrombi in rats

21 January 2018

1 reference

Enhancement of fibrinolysis by EF6265 [(S)-7-amino-2-[[[(R)-2-methyl-1-(3-phenylpropanoylamino)propyl]hydroxyphosphinoyl] methyl]heptanoic acid], a specific inhibitor of plasma carboxypeptidase B.

21 January 2018

1 reference

EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats

21 January 2018

1 reference

Enhancement of rabbit jugular vein thrombolysis by neutralization of factor XI. In vivo evidence for a role of factor XI as an anti-fibrinolytic factor

21 January 2018

1 reference

Murine model of ferric chloride-induced vena cava thrombosis: evidence for effect of potato carboxypeptidase inhibitor

21 January 2018

1 reference

Progress in metallocarboxypeptidases and their small molecular weight inhibitors

21 January 2018

1 reference

Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis

21 January 2018

1 reference

450 million years of hemostasis.

21 January 2018

1 reference

On the specific interaction between the lysine-binding sites in plasmin and complementary sites in α2-antiplasmin and in fibrinogen

21 January 2018

1 reference

Carboxypeptidase U (TAFIa) prevents lysis from proceeding into the propagation phase through a threshold-dependent mechanism

21 January 2018

1 reference

The intrinsic threshold of the fibrinolytic system is modulated by basic carboxypeptidases, but the magnitude of the antifibrinolytic effect of activated thrombin-activable fibrinolysis inhibitor is masked by its instability

21 January 2018

1 reference

Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase

21 January 2018

1 reference

Increased zymogen activity of thrombin-activatable fibrinolysis inhibitor prolongs clot lysis.

21 January 2018

1 reference

An update on the role of carboxypeptidase U (TAFIa) in fibrinolysis

21 January 2018

1 reference

Low thrombin activatable fibrinolysis inhibitor activity levels are associated with an increased risk of a first myocardial infarction in men

21 January 2018

1 reference

Thrombin activatable fibrinolysis inhibitor activation peptide shows association with all major subtypes of ischemic stroke and with TAFI gene variation

21 January 2018

1 reference

The decrease in procarboxypeptidase U (TAFI) concentration in acute ischemic stroke correlates with stroke severity, evolution and outcome

21 January 2018

1 reference

Convalescent plasma levels of TAFI activation peptide predict death and recurrent vascular events in ischemic stroke survivors

21 January 2018

1 reference

High thrombin activatable fibrinolysis inhibitor levels are associated with an increased risk of premature peripheral arterial disease

21 January 2018

1 reference

Thrombin-activatable fibrinolysis inhibitor (TAFI) deficiency is compatible with murine life

21 January 2018

1 reference

In vivo regulation of plasminogen function by plasma carboxypeptidase B.

21 January 2018

1 reference

Demonstration of enhanced endogenous fibrinolysis in thrombin activatable fibrinolysis inhibitor-deficient mice.

21 January 2018

1 reference

Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N.

21 January 2018

1 reference

Thrombin Activatable Fibrinolysis Inhibitor, a Potential Regulator of Vascular Inflammation

21 January 2018

1 reference

Pro-carboxypeptidase R cleaves bradykinin following activation

21 January 2018

1 reference

Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma

21 January 2018

1 reference

Requirement and role of C5a in acute lung inflammatory injury in rats

21 January 2018

1 reference

A role for C5a in augmenting IgG-dependent histamine release from basophils in chronic urticaria

21 January 2018

1 reference

Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo

21 January 2018

1 reference

Evolutionary assembly of blood coagulation proteins

21 January 2018

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Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI-1

21 January 2018

1 reference

Activated thrombin activatable fibrinolysis inhibitor levels are associated with the risk of cardiovascular death in patients with coronary artery disease: the AtheroGenestudy

21 January 2018

1 reference