(Q38121505)

29 August 2017

title

Potential benefits of rho-kinase inhibition in arterial hypertension (English)

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29 August 2017

Olaf Grisk

1

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29 August 2017

publication date

1 October 2013

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Current Hypertension Reports

29 August 2017

published in

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29 August 2017

volume

15

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29 August 2017

issue

5

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29 August 2017

page(s)

506-513

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Blood pressure and the global burden of disease 2000. Part 1: estimates of blood pressure levels

29 August 2017

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21 January 2018

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ROCK inhibitor (Y-27632) disrupts somitogenesis in chick embryos

21 January 2018

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Neural crest cell survival is dependent on Rho kinase and is required for development of the mid face in mouse embryos

21 January 2018

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Possible role of the RhoC/ROCK pathway in progression of clear cell renal cell carcinoma.

21 January 2018

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RACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathway

21 January 2018

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Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death

21 January 2018

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ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

21 January 2018

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

21 January 2018

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Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor

21 January 2018

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Chroman-3-amides as potent Rho kinase inhibitors

21 January 2018

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Potent, selective and orally bioavailable dihydropyrimidine inhibitors of Rho kinase (ROCK1) as potential therapeutic agents for cardiovascular diseases

21 January 2018

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Benzimidazole- and benzoxazole-based inhibitors of Rho kinase

21 January 2018

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Elaborate ligand-based modeling reveal new submicromolar Rho kinase inhibitors

21 January 2018

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Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors

21 January 2018

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Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase

21 January 2018

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Inhibition of renal rho kinase attenuates ischemia/reperfusion-induced injury

21 January 2018

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Is targeting eNOS a key mechanistic insight of cardiovascular defensive potentials of statins?

21 January 2018

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Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

21 January 2018

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Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß 42 by Inhibiting Rho

21 January 2018

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Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition

21 January 2018

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Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2.

21 January 2018

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Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans.

21 January 2018

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Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries

21 January 2018

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Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction

21 January 2018

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Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction

21 January 2018

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Calcium channel blocker and Rho-associated kinase activity in patients with hypertension

21 January 2018

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Procontractile G protein-mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling.

21 January 2018

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ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells

21 January 2018

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Rho-ROCK-LIMK-cofilin pathway regulates shear stress activation of sterol regulatory element binding proteins

21 January 2018

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RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.

21 January 2018

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The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells.

21 January 2018

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Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat

21 January 2018

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Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans

21 January 2018

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Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil

21 January 2018

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Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans

21 January 2018

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Role of rho-kinase in the regulation of vascular tone in hypertensive renal transplant recipients

21 January 2018

1 reference

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Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity

21 January 2018

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Interactions among genetic variants from contractile pathway of vascular smooth muscle cell in essential hypertension susceptibility of Chinese Han population.

21 January 2018

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A major haplotype block at the rho-associated kinase 2 locus is associated with a lower risk of hypertension in a recessive manner: the HYPGENE study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Rho-kinase inhibition reduces pressure-mediated autoregulatory adjustments in afferent arteriolar diameter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Regulation of epithelial tubule formation by Rho family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Tumor necrosis factor α decreases nitric oxide synthase type 3 expression primarily via Rho/Rho kinase in the thick ascending limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Endothelin-1-induced activation of rat renal pelvic contractions depends on cyclooxygenase-1 and Rho kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Genetic variants in Arhgef11 are associated with kidney injury in the Dahl salt-sensitive rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Eplerenone shows renoprotective effect by reducing LOX-1-mediated adhesion molecule, PKCepsilon-MAPK-p90RSK, and Rho-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Fasudil, a Rho-kinase inhibitor, reverses L-NAME exacerbated severe nephrosclerosis in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Renal expression of arachidonic acid metabolizing enzymes and RhoA/Rho kinases in fructose insulin resistant hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Ipragliflozin and other sodium-glucose cotransporter-2 (SGLT2) inhibitors in the treatment of type 2 diabetes: preclinical and clinical data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Inhibition of Rho-kinase in the brainstem augments baroreflex control of heart rate in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Pressor response induced by central angiotensin II is mediated by activation of Rho/Rho-kinase pathway via AT1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Fasudil attenuates sympathetic nervous activity in the adrenal medulla of spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Stimulation of norepinephrine transporter function by fasudil, a Rho kinase inhibitor, in cultured bovine adrenal medullary cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0373-0

Blood pressure and the global burden of disease 2000. Part II: estimates of attributable burden

21 January 2018

1 reference

12 December 2020

Trans-synaptic induction of adrenal tyrosine hydroxylase.

1 reference

12 December 2020

Inhibition of Rho-kinase attenuates nephrosclerosis and improves survival in salt-loaded spontaneously hypertensive stroke-prone rats

1 reference

12 December 2020

Renal microvascular constriction to membrane depolarization and other stimuli: pivotal role for rho-kinase

1 reference

12 December 2020

Renal sympathetic denervation for treatment of drug-resistant hypertension: one-year results from the Symplicity HTN-2 randomized, controlled trial

1 reference

12 December 2020

Rho kinase and Ca2+ entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs promote axon regeneration via RhoA inhibition

1 reference

12 December 2020

Long-term administration of rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats

1 reference

12 December 2020

Systemic availability of the active metabolite hydroxy-fasudil after administration of fasudil to different sites of the human gastrointestinal tract

1 reference

12 December 2020

10.1007/S11906-013-0373-0

Identifiers

DOI

1 reference

Dimensions Publication ID

29 August 2017

1001742758

0 references

1 reference