(Q38122700)

29 August 2017

Keeping mitochondria in shape: a matter of life and death (English)

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29 August 2017

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Luca Scorrano

1

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29 August 2017

1 August 2013

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European Journal of Clinical Investigation

29 August 2017

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29 August 2017

43

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29 August 2017

8

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29 August 2017

886-893

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Chemiosmotic hypothesis of oxidative phosphorylation

29 August 2017

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

21 January 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

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Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

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(De)constructing mitochondria: what for?

21 January 2018

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An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship

21 January 2018

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Cell death: critical control points

21 January 2018

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Mitochondrial shape changes: orchestrating cell pathophysiology.

21 January 2018

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The fine structure of mitochondria

21 January 2018

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The internal structure of mitochondria

21 January 2018

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Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria

21 January 2018

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Mitochondria are morphologically and functionally heterogeneous within cells.

21 January 2018

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Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate

21 January 2018

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Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae

21 January 2018

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Mitochondrial dynamics in mammalian health and disease

21 January 2018

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Shared components of mitochondrial and peroxisomal division

21 January 2018

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Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells

21 January 2018

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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

21 January 2018

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Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin

21 January 2018

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Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

21 January 2018

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Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

21 January 2018

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CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology

21 January 2018

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Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

21 January 2018

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Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death

21 January 2018

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Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

21 January 2018

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

21 January 2018

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Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli

21 January 2018

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Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia

21 January 2018

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The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle

21 January 2018

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hFis1, a novel component of the mammalian mitochondrial fission machinery

21 January 2018

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Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1

21 January 2018

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The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

21 January 2018

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Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

21 January 2018

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The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis

21 January 2018

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

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High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy

21 January 2018

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Mitochondrial fission and remodelling contributes to muscle atrophy.

21 January 2018

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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

21 January 2018

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The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

21 January 2018

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MiD49 and MiD51, new components of the mitochondrial fission machinery

21 January 2018

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Two Mitofusin Proteins, Mammalian Homologues of FZO, with Distinct Functions Are Both Required for Mitochondrial Fusion

21 January 2018

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Structural basis of mitochondrial tethering by mitofusin complexes.

21 January 2018

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Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

21 January 2018

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Dysregulation of HSG triggers vascular proliferative disorders

21 January 2018

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Mitofusin 2 tethers endoplasmic reticulum to mitochondria

21 January 2018

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OPA1 requires mitofusin 1 to promote mitochondrial fusion

21 January 2018

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The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

21 January 2018

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OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria

21 January 2018

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Quality control of mitochondria: protection against neurodegeneration and ageing

21 January 2018

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Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

21 January 2018

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Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage

21 January 2018

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OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

21 January 2018

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Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

21 January 2018

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Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

21 January 2018

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Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

21 January 2018

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OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

21 January 2018

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Orchestration of lymphocyte chemotaxis by mitochondrial dynamics

21 January 2018

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Mitochondrial regulation of store-operated calcium signaling in T lymphocytes

21 January 2018

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Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria

21 January 2018

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Membrane architecture of mitochondria in neurons of the central nervous system

21 January 2018

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Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis

21 January 2018

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Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 January 2018

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Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA

21 January 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

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The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

21 January 2018

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

21 January 2018

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Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

21 January 2018

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Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons.

21 January 2018

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

21 January 2018

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Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization

21 January 2018

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Role of Bax and Bak in mitochondrial morphogenesis

21 January 2018

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

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Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

21 January 2018

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Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.

21 January 2018

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Opening the doors to cytochrome c: changes in mitochondrial shape and apoptosis.

21 January 2018

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A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

21 January 2018

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Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization

21 January 2018

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The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms

21 January 2018

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Optic atrophy 1-dependent mitochondrial remodeling controls steroidogenesis in trophoblasts.

21 January 2018

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The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock

21 January 2018

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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

21 January 2018

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Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

21 January 2018

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Mitochondria supply membranes for autophagosome biogenesis during starvation

21 January 2018

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ER tubules mark sites of mitochondrial division

21 January 2018

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Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

21 January 2018

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PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis

21 January 2018

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Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

21 January 2018

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Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk

21 January 2018

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Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

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MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

21 January 2018

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Trichoplein/mitostatin regulates endoplasmic reticulum-mitochondria juxtaposition

21 January 2018

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An ER-mitochondria tethering complex revealed by a synthetic biology screen

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/ECI.12135

1 reference

29 August 2017

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PubMed ID

23869410