(Q38124366)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Robert Stöhr

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

language of work or name

English

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publication date

1 August 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

454

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6 March 2020

issue

1

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6 March 2020

page(s)

1-11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

Etiology of insulin resistance

6 March 2020

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Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells

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Insulin stimulates both endothelin and nitric oxide activity in the human forearm.

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Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosis

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Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

21 January 2018

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Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice

21 January 2018

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Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice

21 January 2018

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Cell biology of atherosclerosis

21 January 2018

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Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: a balanced overview

21 January 2018

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Insulin resistance and the endothelium

21 January 2018

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Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage

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Inflammation in atherosclerosis: transition from theory to practice

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Macrophages, inflammation, and insulin resistance

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Alternative macrophage activation and metabolism

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

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Blood monocytes consist of two principal subsets with distinct migratory properties

21 January 2018

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Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

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Alternative activation of macrophages: an immunologic functional perspective

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

21 January 2018

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HIF-1alpha is essential for myeloid cell-mediated inflammation

21 January 2018

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Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E

21 January 2018

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Premature coronary-artery atherosclerosis in systemic lupus erythematosus

21 January 2018

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A glimpse on the phenomenon of macrophage polarization during atherosclerosis

21 January 2018

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Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

21 January 2018

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Importance of primary capture and L-selectin-dependent secondary capture in leukocyte accumulation in inflammation and atherosclerosis in vivo.

21 January 2018

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Inflammation, atherosclerosis, and coronary artery disease

21 January 2018

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Macrophage diversity and polarization in atherosclerosis: a question of balance

21 January 2018

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Stabilization of atherosclerotic plaques: new mechanisms and clinical targets

21 January 2018

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The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

21 January 2018

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Macrophage plasticity in experimental atherosclerosis

21 January 2018

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

21 January 2018

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Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease

21 January 2018

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Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques

21 January 2018

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Concept of vulnerable/unstable plaque

21 January 2018

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Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.

21 January 2018

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Mechanisms and consequences of efferocytosis in advanced atherosclerosis

21 January 2018

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Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

21 January 2018

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Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.

21 January 2018

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

21 January 2018

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

21 January 2018

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A central role for JNK in obesity and insulin resistance

21 January 2018

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JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

21 January 2018

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Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation

21 January 2018

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Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis

21 January 2018

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Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance

21 January 2018

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Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

21 January 2018

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Insulin suppresses endotoxin-induced oxidative, nitrosative, and inflammatory stress in humans

21 January 2018

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Suppressive effect of insulin infusion on chemokines and chemokine receptors

21 January 2018

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Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect?

21 January 2018

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FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

21 January 2018

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Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

21 January 2018

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Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance

21 January 2018

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Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

21 January 2018

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Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis

21 January 2018

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Role for Akt3/protein kinase Bgamma in attainment of normal brain size

21 January 2018

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Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease

21 January 2018

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Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice

21 January 2018

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Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization

21 January 2018

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FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis

21 January 2018

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Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice

21 January 2018

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Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.

21 January 2018

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IKK-beta links inflammation to obesity-induced insulin resistance

21 January 2018

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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

21 January 2018

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Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

21 January 2018

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MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity

21 January 2018

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TLR4 links innate immunity and fatty acid-induced insulin resistance

21 January 2018

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Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages.

21 January 2018

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Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

21 January 2018

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Obesity and lipodystrophy--where do the circles intersect?

21 January 2018

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Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

21 January 2018

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Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability

21 January 2018

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Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha

21 January 2018

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The role of ADAM17 in metabolic inflammation.

21 January 2018

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Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice

21 January 2018

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TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1.

21 January 2018

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Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages

21 January 2018

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Decreased IRS2 and TIMP3 expression in monocytes from offspring of type 2 diabetic patients is correlated with insulin resistance and increased intima-media thickness

21 January 2018

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TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice.

21 January 2018

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Macrophage ADAM17 deficiency augments CD36-dependent apoptotic cell uptake and the linked anti-inflammatory phenotype

21 January 2018

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Glucose tolerance and the risk of cardiovascular disease: the Zutphen Study.

21 January 2018

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Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group

21 January 2018

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Immune modulation of atherosclerosis

21 January 2018

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T cells in atherogenesis: for better or for worse?

21 January 2018

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Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction.

21 January 2018

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Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20130121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23889252%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference