(Q38125425)

29 August 2017

Virus-encoded endonucleases: expected and novel functions (English)

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29 August 2017

G Sullivan Read

1

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PubMed ID

23900973

29 August 2017

language of work or name

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30 July 2013

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Wiley interdisciplinary reviews. RNA

29 August 2017

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29 August 2017

4

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29 August 2017

6

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29 August 2017

693-708

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Mechanisms of endonuclease-mediated mRNA decay

29 August 2017

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Many roads to maturity: microRNA biogenesis pathways and their regulation

21 January 2018

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mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein

21 January 2018

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The herpes simplex virus 1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell type-dependent manner.

21 January 2018

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Evidence for translational regulation by the herpes simplex virus virion host shutoff protein

21 January 2018

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mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease

21 January 2018

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mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.

21 January 2018

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mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor

21 January 2018

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The virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.

21 January 2018

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Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus

21 January 2018

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Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41

21 January 2018

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Early Virion-associated Suppression of Cellular Protein Synthesis by Herpes Simplex Virus is Accompanied by Inactivation of mRNA

21 January 2018

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Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs

21 January 2018

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Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state

21 January 2018

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The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection

21 January 2018

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Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein

21 January 2018

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The virion host shutoff function of herpes simplex virus degrades the 5' end of a target mRNA before the 3' end.

21 January 2018

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Selective ablation of virion host shutoff protein RNase activity attenuates herpes simplex virus 2 in mice

21 January 2018

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Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants

21 January 2018

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Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice

21 January 2018

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Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?

21 January 2018

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Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.

21 January 2018

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The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.

21 January 2018

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Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo

21 January 2018

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The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells

21 January 2018

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The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

21 January 2018

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Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.

21 January 2018

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Transcriptional response of a common permissive cell type to infection by two diverse alphaherpesviruses

21 January 2018

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Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.

21 January 2018

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The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific

21 January 2018

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Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs

21 January 2018

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The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs

21 January 2018

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Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene

21 January 2018

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Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.

21 January 2018

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The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.

21 January 2018

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MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

21 January 2018

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The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

21 January 2018

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Herpes simplex virus ICP27 activation of stress kinases JNK and p38.

21 January 2018

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Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase

21 January 2018

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Analysis of herpes simplex virus-induced mRNA destabilizing activity using an in vitro mRNA decay system

21 January 2018

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The Stress-Inducible Immediate-Early Responsive Gene IEX-1 Is Activated in Cells Infected with Herpes Simplex Virus 1, but Several Viral Mechanisms, Including 3′ Degradation of Its RNA, Preclude Expression of the Gene

21 January 2018

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The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins

21 January 2018

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The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A

21 January 2018

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mRNA helicases: the tacticians of translational control

21 January 2018

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Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

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eIF4A: the godfather of the DEAD box helicases

21 January 2018

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Interactions between eIF4AI and its accessory factors eIF4B and eIF4H

21 January 2018

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The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase

21 January 2018

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Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation

21 January 2018

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Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F.

21 January 2018

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Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H

21 January 2018

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Emerging therapeutics targeting mRNA translation

21 January 2018

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Selective pharmacological targeting of a DEAD box RNA helicase.

21 January 2018

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Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs

21 January 2018

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The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection

21 January 2018

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Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking

21 January 2018

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The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes

21 January 2018

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The vhs1 mutant form of herpes simplex virus virion host shutoff protein retains significant internal ribosome entry site-directed RNA cleavage activity.

21 January 2018

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Eukaryotic initiation factors 4G and 4A mediate conformational changes downstream of the initiation codon of the encephalomyocarditis virus internal ribosomal entry site

21 January 2018

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Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation

21 January 2018

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Translation eukaryotic initiation factor 4G recognizes a specific structural element within the internal ribosome entry site of encephalomyocarditis virus RNA.

21 January 2018

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Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus

21 January 2018

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Initiation of protein synthesis from the A site of the ribosome

21 January 2018

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A common strategy for host RNA degradation by divergent viruses

21 January 2018

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Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA

21 January 2018

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Deletion of the herpes simplex virus 1 UL49 gene results in mRNA and protein translation defects that are complemented by secondary mutations in UL41.

21 January 2018

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VP22 of herpes simplex virus 1 promotes protein synthesis at late times in infection and accumulation of a subset of viral mRNAs at early times in infection

21 January 2018

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Characterization of a UL49-null mutant: VP22 of herpes simplex virus type 1 facilitates viral spread in cultured cells and the mouse cornea

21 January 2018

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Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.

21 January 2018

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Packaging of the virion host shutoff (Vhs) protein of herpes simplex virus: two forms of the Vhs polypeptide are associated with intranuclear B and C capsids, but only one is associated with enveloped virions

21 January 2018

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Control of VP16 translation by the herpes simplex virus type 1 immediate-early protein ICP27.

21 January 2018

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The virion host shutoff protein of herpes simplex virus inhibits reporter gene expression in the absence of other viral gene products

21 January 2018

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Translational regulation of gene expression during conditions of cell stress

21 January 2018

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Re-programming of translation following cell stress allows IRES-mediated translation to predominate

21 January 2018

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Coordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1.

21 January 2018

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Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover

21 January 2018

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Getting the message direct manipulation of host mRNA accumulation during gammaherpesvirus lytic infection

21 January 2018

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Host shutoff is a conserved phenotype of gammaherpesvirus infection and is orchestrated exclusively from the cytoplasm

21 January 2018

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Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

21 January 2018

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The exonuclease and host shutoff functions of the SOX protein of Kaposi's sarcoma-associated herpesvirus are genetically separable

21 January 2018

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Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation

21 January 2018

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Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation.

21 January 2018

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21 January 2018

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Influenza virus mRNA translation revisited: is the eIF4E cap-binding factor required for viral mRNA translation?

21 January 2018

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Erratum: Regulation of cytoplasmic mRNA decay

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WRNA.1188

1 reference

29 August 2017

1 reference

PubMed ID

23900973