(Q38130854)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Metalloproteinases and their natural inhibitors in inflammation and immunity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

0 references

1

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8 March 2020

author name string

Aditya Murthy

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Ashley Weiss

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

publication date

1 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

8 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

649-665

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969736%20AND%20SRC:MED&resulttype=core&format=json

Collagenolytic activity in amphibian tissues: a tissue culture assay

8 March 2020

cites work

1 reference

Molecular characterization and expression of the gene encoding human erythroid-potentiating activity

31 March 2020

1 reference

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

31 March 2020

1 reference

Structure and function of matrix metalloproteinases and TIMPs

31 March 2020

1 reference

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

31 March 2020

1 reference

Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure.

31 March 2020

1 reference

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

31 March 2020

1 reference

The regulation of matrix metalloproteinases and their inhibitors.

31 March 2020

1 reference

Epigenetic regulation of matrix metalloproteinases and their collagen substrates in cancer

31 March 2020

1 reference

Cellular turnover and extracellular matrix remodeling in female reproductive tissues: functions of metalloproteinases and their inhibitors

31 March 2020

1 reference

Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.

31 March 2020

1 reference

Stromal TIMP3 regulates liver lymphocyte populations and provides protection against Th1 T cell-driven autoimmune hepatitis

31 March 2020

1 reference

Purification and identification of 91-kDa neutrophil gelatinase. Release by the activating peptide interleukin-8.

31 March 2020

1 reference

Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis.

31 March 2020

1 reference

Direct proteomic quantification of the secretome of activated immune cells.

31 March 2020

1 reference

Functional interactions between matrix metalloproteinases and glycosaminoglycans

31 March 2020

1 reference

The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3

31 March 2020

1 reference

Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity is in the detail

31 March 2020

1 reference

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

31 March 2020

1 reference

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site

31 March 2020

1 reference

TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.

31 March 2020

1 reference

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17.

31 March 2020

1 reference

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS

31 March 2020

1 reference

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

31 March 2020

1 reference

Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.

31 March 2020

1 reference

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.

31 March 2020

1 reference

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

31 March 2020

1 reference

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

31 March 2020

1 reference

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

31 March 2020

1 reference

An essential role for ectodomain shedding in mammalian development

31 March 2020

1 reference

Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages

31 March 2020

1 reference

Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock

31 March 2020

1 reference

Tissue inhibitor of metalloproteinase 3 regulates TNF-dependent systemic inflammation.

31 March 2020

1 reference

Abnormal TNF activity in Timp3 −/− mice leads to chronic hepatic inflammation and failure of liver regeneration

31 March 2020

1 reference

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

31 March 2020

1 reference

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

31 March 2020

1 reference

Lymphotoxin-alphabeta heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis

31 March 2020

1 reference

Fine-tuning of dendritic cell biology by the TNF superfamily

31 March 2020

1 reference

Matrix metalloproteinase-2 conditions human dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and OX40L-dependent pathway

31 March 2020

1 reference

Cutting edge: soluble IL-6R is produced by IL-6R ectodomain shedding in activated CD4 T cells

31 March 2020

1 reference

ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by gamma-secretase

31 March 2020

1 reference

Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding

31 March 2020

1 reference

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

31 March 2020

1 reference

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

31 March 2020

1 reference

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

31 March 2020

1 reference

Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism.

31 March 2020

1 reference

Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress

31 March 2020

1 reference

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism

31 March 2020

1 reference

Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis

31 March 2020

1 reference

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

31 March 2020

1 reference

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

31 March 2020

1 reference

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

31 March 2020

1 reference

The Helicobacter pylori virulence effector CagA abrogates human β-defensin 3 expression via inactivation of EGFR signaling

31 March 2020

1 reference

Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit

31 March 2020

1 reference

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

31 March 2020

1 reference

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

31 March 2020

1 reference

Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region

31 March 2020

1 reference

Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

31 March 2020

1 reference

Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling

31 March 2020

1 reference

ADAM10 is essential for proteolytic activation of Notch during thymocyte development.

31 March 2020

1 reference

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

31 March 2020

1 reference

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo

31 March 2020

1 reference

Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17.

31 March 2020

1 reference

Inflammatory skin and bowel disease linked to ADAM17 deletion

31 March 2020

1 reference

Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin

31 March 2020

1 reference

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity

31 March 2020

1 reference

The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling

31 March 2020

1 reference

Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

31 March 2020

1 reference

Epidermal ADAM17 is dispensable for notch activation

31 March 2020

1 reference

The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis

31 March 2020

1 reference

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.

31 March 2020

1 reference

Inflammasomes in health and disease

31 March 2020

1 reference

Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1beta

31 March 2020

1 reference

Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation

31 March 2020

1 reference

Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli

31 March 2020

1 reference

Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

31 March 2020

1 reference

LPS responsiveness and neutrophil chemotaxis in vivo require PMN MMP-8 activity

31 March 2020

1 reference

In vivo processing of CXCL5 (LIX) by matrix metalloproteinase (MMP)-2 and MMP-9 promotes early neutrophil recruitment in IL-1β-induced peritonitis.

31 March 2020

1 reference

Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3

31 March 2020

1 reference

Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice

31 March 2020

1 reference

Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury

31 March 2020

1 reference

L-selectin: mechanisms and physiological significance of ectodomain cleavage.

31 March 2020

1 reference

ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment

31 March 2020

1 reference

Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites

31 March 2020

1 reference

Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.

31 March 2020

1 reference

Innate immune responses are increased in chronic obstructive pulmonary disease

31 March 2020

1 reference

Matrix metalloproteinase-9 increases in the sputum from allergic occupational asthma patients after specific inhalation challenge

31 March 2020

1 reference

ADAMTS-12 metalloprotease is necessary for normal inflammatory response

31 March 2020

1 reference

ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils

31 March 2020

1 reference

TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence.

31 March 2020

1 reference

Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB

31 March 2020

1 reference

MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function.

31 March 2020

1 reference

Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx

31 March 2020

1 reference

Shedding and gamma-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43.

31 March 2020

1 reference

Presenilin/gamma-secretase and alpha-secretase-like peptidases cleave human MHC Class I proteins

31 March 2020

1 reference

Serum CD40/CD40L system in Graves' disease and Hashimoto's thyroiditis related to soluble Fas, FasL and humoral markers of autoimmune response

31 March 2020

1 reference

Modulation of integrin α4β1 by ADAM28 promotes lymphocyte adhesion and transendothelial migration

31 March 2020

1 reference

The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes

31 March 2020

1 reference

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

31 March 2020

1 reference

Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands.

31 March 2020

1 reference

Cutting edge: the metalloproteinase ADAM17/TNF-alpha-converting enzyme regulates proteolytic shedding of the MHC class I-related chain B protein

31 March 2020

1 reference

TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1.

31 March 2020

1 reference

Overexpression of tissue inhibitor of metalloproteinase 3 in macrophages reduces atherosclerosis in low-density lipoprotein receptor knockout mice

31 March 2020

1 reference

Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology

31 March 2020

1 reference

Cell distribution differences of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in patients with Kawasaki disease

31 March 2020

1 reference

Regulation of Th1/Th2 polarization by tissue inhibitor of metalloproteinase-3 via modulating dendritic cells

31 March 2020

1 reference

Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis

31 March 2020

1 reference

Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Hemopexin domains as multifunctional liganding modules in matrix metalloproteinases and other proteins

31 March 2020

1 reference

TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs

31 March 2020

1 reference

TIMP-3 recruits quiescent hematopoietic stem cells into active cell cycle and expands multipotent progenitor pool

31 March 2020

1 reference

Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo

31 March 2020

1 reference

Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1.

31 March 2020

1 reference

Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels

31 March 2020

1 reference

Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors

31 March 2020

1 reference

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

31 March 2020

1 reference

Defensins: antimicrobial peptides of innate immunity

31 March 2020

1 reference

Human neutrophils secrete gelatinase B in vitro and in vivo in response to endotoxin and proinflammatory mediators

31 March 2020

1 reference

Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis

31 March 2020

1 reference

Matrix metalloproteinase 9 (MMP-9)-dependent processing of βig-h3 protein regulates cell migration, invasion, and adhesion

31 March 2020

1 reference

Expression of stromelysin-3 in atherosclerotic lesions: regulation via CD40-CD40 ligand signaling in vitro and in vivo

31 March 2020

1 reference

Oxidatively modified high density lipoprotein promotes inflammatory response in human monocytes-macrophages by enhanced production of ROS, TNF-α, MMP-9, and MMP-2.

31 March 2020

1 reference

Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: role of activated macrophages and inflammatory cytokines

31 March 2020

1 reference

Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase

31 March 2020

1 reference

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

31 March 2020

1 reference

Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability

31 March 2020

1 reference

Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases

31 March 2020

1 reference

Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses

31 March 2020

1 reference

Matrix metalloprotease 1a deficiency suppresses tumor growth and angiogenesis.

31 March 2020

1 reference

Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy.

31 March 2020

1 reference

Matrix metalloproteinase deficiencies affect contact hypersensitivity: stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response

31 March 2020

1 reference

Matrix metalloproteinase-3 (stromelysin-1) in acute inflammatory tissue injury

31 March 2020

1 reference

Enteric defensins are essential regulators of intestinal microbial ecology

31 March 2020

1 reference

Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).

31 March 2020

1 reference

Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced toll-like receptor signaling

31 March 2020

1 reference

Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis

31 March 2020

1 reference

Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae

31 March 2020

1 reference

Macrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases

31 March 2020

1 reference

Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy

31 March 2020

1 reference

Deficiency of matrix metalloproteinase-13 increases inflammation after acute lung injury

31 March 2020

1 reference

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

31 March 2020

1 reference

MMP19 is essential for T cell development and T cell-mediated cutaneous immune responses

31 March 2020

1 reference

Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans

31 March 2020

1 reference

Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice

31 March 2020

1 reference

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation

31 March 2020

1 reference

Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia

31 March 2020

1 reference

ADAM8: a new therapeutic target for asthma

31 March 2020

1 reference

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

31 March 2020

1 reference

The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation

31 March 2020

1 reference

Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.

31 March 2020

1 reference

A novel pathway of aerobic benzoate catabolism in the bacteria Azoarcus evansii and Bacillus stearothermophilus

31 March 2020

1 reference

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice

31 March 2020

1 reference

Mice with tissue inhibitor of metalloproteinases 4 (Timp4) deletion succumb to induced myocardial infarction but not to cardiac pressure overload.

31 March 2020

1 reference

MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease

31 March 2020

1 reference

Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.

31 March 2020

1 reference

Deletion of the mouse meprin beta metalloprotease gene diminishes the ability of leukocytes to disseminate through extracellular matrix

31 March 2020

1 reference

Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease.

31 March 2020

1 reference

The C4 and C2 but not C1 components of complement are responsible for the complement activation triggered by the Ra-reactive factor.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23969736

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gelatinase B functions as regulator and effector in leukocyte biology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23969736

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23969736