(Q38161532)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Pathogenic immune mechanisms at the neuromuscular synapse: the role of specific antibody-binding epitopes in myasthenia gravis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Jan J Verschuuren

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

M G Huijbers

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

A F Lipka

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

J J Plomp

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

S M van der Maarel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

29 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

Journal of Internal Medicine

29 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

12-26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs

29 February 2020

cites work

1 reference

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21 January 2018

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21 January 2018

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A systematic review of population based epidemiological studies in Myasthenia Gravis.

21 January 2018

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An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis

21 January 2018

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An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus

21 January 2018

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The membrane attack complex of complement at the endplate in myasthenia gravis.

21 January 2018

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Anatomy of the antigenic structure of a large membrane autoantigen, the muscle-type nicotinic acetylcholine receptor

21 January 2018

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Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies

21 January 2018

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Acquired slow-channel syndrome: a form of myasthenia gravis with prolonged open time of the acetylcholine receptor channel.

21 January 2018

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Mapping the main immunogenic region and toxin-binding site of the nicotinic acetylcholine receptor

21 January 2018

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Antigenic structure of the human muscle nicotinic acetylcholine receptor main immunogenic region

21 January 2018

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Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits

21 January 2018

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Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity

21 January 2018

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Myasthenogenicity of the main immunogenic region and endogenous muscle nicotinic acetylcholine receptors

21 January 2018

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21 January 2018

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Anti-CTLA-4 antibody treatment triggers determinant spreading and enhances murine myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Breakage of tolerance to hidden cytoplasmic epitopes of the acetylcholine receptor in experimental autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

The significance of erythrocyte antigen site density

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Rapsyn antibodies in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Anti-Heat Shock Protein 70 antibody levels are increased in myasthenia gravis and Guillain-Barré syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Thymic B lymphocyte clones from patients with myasthenia gravis secrete monoclonal striational autoantibodies reacting with myosin, alpha actinin, or actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease

21 January 2018

1 reference

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Specific immunotherapy of experimental myasthenia gravis by a novel mechanism

21 January 2018

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https://api.crossref.org/works/10.1111%2FJOIM.12163

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Effects of the rate of acetylcholine receptor synthesis on the severity of experimental autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Complement associated pathogenic mechanisms in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Antigen-specific modulation of experimental myasthenia gravis: nasal tolerization with recombinant fragments of the human acetylcholine receptor alpha-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Oral tolerance in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Prevention of experimental myasthenia gravis by nasal administration of synthetic acetylcholine receptor T epitope sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Immunosuppression of rat myasthenia gravis by oral administration of a syngeneic acetylcholine receptor fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Mucosal tolerance: a two-edged sword to prevent and treat autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Prevention of experimental autoimmune myasthenia gravis by manipulation of the immune network with a complementary peptide for the acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Expression and characterization of soluble forms of the extracellular domains of the beta, gamma and epsilon subunits of the human muscle acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Expression of soluble ligand- and antibody-binding extracellular domain of human muscle acetylcholine receptor alpha subunit in yeast Pichia pastoris. Role of glycosylation in alpha-bungarotoxin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Antigen-specific apheresis of pathogenic autoantibodies from myasthenia gravis sera.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Recent approaches to the development of antigen-specific immunotherapies for myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Strong association of MuSK antibody-positive myasthenia gravis and HLA-DR14-DQ5

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Response to therapy in myasthenia gravis with anti-MuSK antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Nonresponsiveness to anticholinesterase agents in patients with MuSK-antibody-positive MG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Long-lasting treatment effect of rituximab in MuSK myasthenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Detection and characterization of MuSK antibodies in seronegative myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Clinical fluctuations in MuSK myasthenia gravis are related to antigen-specific IgG4 instead of IgG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Immunoglobulin G4: an odd antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Clinical and experimental features of MuSK antibody positive MG in Japan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Crystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

To build a synapse: signaling pathways in neuromuscular junction assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Biglycan is an extracellular MuSK binding protein important for synapse stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

MuSK is required for anchoring acetylcholinesterase at the neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Lrp4 is a receptor for Agrin and forms a complex with MuSK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

LRP4 serves as a coreceptor of agrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Anti-MuSK autoantibodies block binding of collagen Q to MuSK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

MuSK controls where motor axons grow and form synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Passive and active immunization models of MuSK-Ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Pre- and postsynaptic neuromuscular junction abnormalities in musk myasthenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Are MuSK antibodies the primary cause of myasthenic symptoms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Structural basis of agrin-LRP4-MuSK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

An improved diagnostic assay for Lambert-Eaton myasthenic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

The Lambert-Eaton myasthenic syndrome. A review of 50 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Lambert-Eaton myasthenic syndrome: tumor versus nontumor forms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Differences in clinical features between the Lambert-Eaton myasthenic syndrome with and without cancer: an analysis of 227 published cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Difference in distribution of muscle weakness between myasthenia gravis and the Lambert-Eaton myasthenic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Autonomic dysfunction in the Lambert-Eaton myasthenic syndrome: serologic and clinical correlates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Transient neonatal Lambert-Eaton syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Cross-linking of presynaptic calcium channels: a mechanism of action for Lambert-Eaton myasthenic syndrome antibodies at the mouse neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Inhibition of calcium currents and exocytosis by Lambert-Eaton syndrome antibodies in human lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Molecular determinants of Ca2+ channel function and drug action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Linear B-cell epitopes in Lambert-Eaton myasthenic syndrome defined by cell-free synthetic peptide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Lambert-eaton myasthenic syndrome differential reactivity of tumor versus non-tumor patients to subunits of the voltage-gated calcium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Lambert-Eaton myasthenic syndrome: search for alternative autoimmune targets and possible compensatory mechanisms based on presynaptic calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Antibodies against the calcium channel beta-subunit in Lambert-Eaton myasthenic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Antibodies against the beta subunit of voltage-dependent calcium channels in Lambert-Eaton myasthenic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Antibodies to active zone protein ERC1 in Lambert-Eaton myasthenic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Autoantibodies against M1 muscarinic acetylcholine receptor in myasthenic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Calcium channel subtypes contributing to acetylcholine release from normal, 4-aminopyridine-treated and myasthenic syndrome auto-antibodies-affected neuromuscular junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12163

21 January 2018

Identifiers

DOI

10.1111/JOIM.12163

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json

release_qaznauk4irembpjnaagm72qwka

29 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qaznauk4irembpjnaagm72qwka

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24215230%20AND%20SRC:MED&resulttype=core&format=json