(Q38162995)

30 August 2017

title

Modulating Ca2+ release by the IP3R/Ca2+ channel as a potential therapeutic treatment for neurological diseases (English)

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30 August 2017

Carmen C M Chan

1

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30 August 2017

publication date

1 September 2013

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Pharmaceutical patent analyst

30 August 2017

published in

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30 August 2017

volume

2

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30 August 2017

issue

5

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30 August 2017

page(s)

629-636

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IP3 receptor/Ca2+ channel: from discovery to new signaling concepts

30 August 2017

cites work

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The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor.

21 January 2018

1 reference

Inositol trisphosphate receptor Ca2+ release channels.

21 January 2018

1 reference

The inositol 1,4,5-trisphosphate receptors

21 January 2018

1 reference

Huntington's disease: from pathology and genetics to potential therapies

21 January 2018

1 reference

Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series

21 January 2018

1 reference

Deranged neuronal calcium signaling and Huntington disease.

21 January 2018

1 reference

Role of inositol 1,4,5-trisphosphate receptors in pathogenesis of Huntington's disease and spinocerebellar ataxias

21 January 2018

1 reference

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

21 January 2018

1 reference

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

21 January 2018

1 reference

HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons

21 January 2018

1 reference

Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model

21 January 2018

1 reference

Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

21 January 2018

1 reference

Deranged calcium signaling in Purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias

21 January 2018

1 reference

Purkinje cell long-term depression is prevented by T-588, a neuroprotective compound that reduces cytosolic calcium release from intracellular stores

21 January 2018

1 reference

Human ataxias: a genetic dissection of inositol triphosphate receptor (ITPR1)-dependent signaling

21 January 2018

1 reference

Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.

21 January 2018

1 reference

The pathogenesis of spinocerebellar ataxia

21 January 2018

1 reference

Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.

21 January 2018

1 reference

Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice

21 January 2018

1 reference

Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3

21 January 2018

1 reference

Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16

21 January 2018

1 reference

Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans

21 January 2018

1 reference

Inositol trisphosphate receptor Ca2+ release channels in neurological diseases

21 January 2018

1 reference

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

Cytotoxicity of intracellular aβ42 amyloid oligomers involves Ca2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate

21 January 2018

1 reference

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

21 January 2018

1 reference

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.

21 January 2018

1 reference

ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study

21 January 2018

1 reference

Calcium signaling pathways mediating synaptic potentiation triggered by amyotrophic lateral sclerosis IgG in motor nerve terminals.

21 January 2018

1 reference

Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1

21 January 2018

1 reference

Bcl-2 interaction with the inositol 1,4,5-trisphosphate receptor: role in Ca(2+) signaling and disease

21 January 2018

1 reference

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

21 January 2018

1 reference

Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease

21 January 2018

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A novel recombinant hyperaffinity inositol 1,4,5-trisphosphate (IP(3)) absorbent traps IP(3), resulting in specific inhibition of IP(3)-mediated calcium signaling

21 January 2018

1 reference

Selective destruction of protein function by chromophore-assisted laser inactivation

21 January 2018

1 reference

Spatiotemporal laser inactivation of inositol 1,4,5-trisphosphate receptors using synthetic small-molecule probes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/PPA.13.42

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30 August 2017

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