(Q38168664)

30 August 2017

title

Mitochondrial dysfunction in the pathophysiology of renal diseases (English)

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30 August 2017

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Ruochen Che

1

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30 August 2017

Yanggang Yuan

series ordinal

2

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30 August 2017

Songming Huang

series ordinal

3

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30 August 2017

Aihua Zhang

series ordinal

4

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30 August 2017

publication date

4 December 2013

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American Journal of Physiology - Renal Physiology

30 August 2017

published in

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30 August 2017

volume

306

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30 August 2017

issue

4

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30 August 2017

page(s)

F367-78

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The pathogenesis of acute kidney injury and the toxic triangle of oxygen, reactive oxygen species and nitric oxide

30 August 2017

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Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

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Inhibition of MTOR disrupts autophagic flux in podocytes

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IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses.

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Mitochondrial tRNA(Phe) mutation as a cause of end-stage renal disease in childhood

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The spectrum of focal segmental glomerulosclerosis: new insights

21 January 2018

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Cyclosporine A-induced apoptosis in renal tubular cells is related to oxidative damage and mitochondrial fission

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Molecular mechanisms of superoxide production by the mitochondrial respiratory chain.

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A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease

21 January 2018

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Ethylmalonic encephalopathy associated with crescentic glomerulonephritis

21 January 2018

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Renal involvement in mitochondrial cytopathies

21 January 2018

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"Bartter-like" phenotype in Kearns-Sayre syndrome.

21 January 2018

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Initial experience in the treatment of inherited mitochondrial disease with EPI-743.

21 January 2018

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Oxygen and renal metabolism

21 January 2018

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21 January 2018

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Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite

21 January 2018

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Role of mitofusin 2 in the renal stress response

21 January 2018

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Renal tubular involvement mimicking Bartter syndrome in a patient with Kearns-Sayre syndrome.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial dysregulation and oxidative stress in patients with chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Focal segmental glomerulosclerosis associated with mitochondrial cytopathy: report of two cases with special emphasis on podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

The spectrum of systemic involvement in adults presenting with renal lesion and mitochondrial tRNA(Leu) gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Multiphoton imaging reveals differences in mitochondrial function between nephron segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Apoptosis and acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Cellular adaptive changes in AKI: mitigating renal hypoxic injury.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

IHG-1 promotes mitochondrial biogenesis by stabilizing PGC-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

CoQ(10) deficiencies and MNGIE: two treatable mitochondrial disorders

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Baculovirus complementation restores a novel NDUFAF2 mutation causing complex I deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial encephalocardio-myopathy with early neonatal onset due to TMEM70 mutation

21 January 2018

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The many faces of insulin-like peptide signalling in the brain

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Aldosterone-induced mesangial cell proliferation is mediated by EGF receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Podocyte energy metabolism and glomerular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial causes of renal insufficiency and hearing loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Uric acid and chronic kidney disease: which is chasing which?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Phase I trial of rosiglitazone in FSGS: I. Report of the FONT Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Superoxide enhances Na-K-2Cl cotransporter activity in the thick ascending limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Allopurinol benefits left ventricular mass and endothelial dysfunction in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Correction of the consequences of mitochondrial 3243A>G mutation in the MT-TL1 gene causing the MELAS syndrome by tRNA import into mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Renal glutathione transport: Identification of carriers, physiological functions, and controversies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

A mitochondrial DNA deletion presenting with corneal clouding and severe Fanconi syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

PKC-delta promotes renal tubular cell apoptosis associated with proteinuria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

New insights into epithelial-mesenchymal transition in kidney fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Comparing genomic expression patterns across species identifies shared transcriptional profile in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial disease--its impact, etiology, and pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

An autopsy case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with intestinal bleeding in chronic renal failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Unraveling the biological roles of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Follow-up of phase I trial of adalimumab and rosiglitazone in FSGS: III. Report of the FONT study group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Chronic kidney disease, severe arterial and arteriolar sclerosis and kidney neoplasia: on the spectrum of kidney involvement in MELAS syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial dysfunction and molecular pathways of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Diagnosis of mitochondrial DNA depletion syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Renal parenchymal oxygenation and hypoxia adaptation in acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Antenatal mitochondrial disease caused by mitochondrial ribosomal protein (MRPS22) mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Renal cell carcinoma in a pediatric patient with an inherited mitochondrial mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Effect of thiazolidinediones on albuminuria and proteinuria in diabetes: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Apoptosis in podocytes induced by TGF-beta and Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Renal involvement in MELAS syndrome - a series of 5 cases and review of the literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Oxidative stress, anti-oxidant therapies and chronic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Cytochrome c: potential as a noninvasive biomarker of drug-induced acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Calpains, mitochondria, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial dysfunction is an early event in aldosterone-induced podocyte injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

J-shaped mortality relationship for uric acid in CKD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Amelioration of rhabdomyolysis-induced renal mitochondrial injury and apoptosis through suppression of Drp-1 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Unusual clinical presentations in four cases of Leigh disease, cytochrome C oxidase deficiency, and SURF1 gene mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Succinyl-CoA ligase deficiency: a mitochondrial hepatoencephalomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Parkin interacts with Ambra1 to induce mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mutation in the mitochondrial translation elongation factor EFTs results in severe infantile liver failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Early-onset liver mtDNA depletion and late-onset proteinuric nephropathy in Mpv17 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Correcting human mitochondrial mutations with targeted RNA import

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial dysfunction accounts for aldosterone-induced epithelial-to-mesenchymal transition of renal proximal tubular epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

A PPARgamma agonist inhibits aldosterone-induced mesangial cell proliferation by blocking ROS-dependent EGFR intracellular signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Proximal tubular cytochrome c efflux: determinant, and potential marker, of mitochondrial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Role of BNIP3 and NIX in cell death, autophagy, and mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

Mitochondrial dysfunction mediates aldosterone-induced podocyte damage: a therapeutic target of PPARγ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00571.2013

The phenoptosis problem: what is causing the death of an organism? Lessons from acute kidney injury.

21 January 2018

1 reference

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10.1152/AJPRENAL.00571.2013

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference