(Q38169656)

30 August 2017

title

T-cell adoptive immunotherapy for acute lymphoblastic leukemia (English)

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30 August 2017

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Terry J Fry

1

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30 August 2017

Crystal L Mackall

series ordinal

2

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30 August 2017

publication date

1 January 2013

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Hematology / the Education Program of the American Society of Hematology

30 August 2017

published in

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30 August 2017

volume

2013

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30 August 2017

page(s)

348-353

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

30 August 2017

cites work

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Pediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: the GRAALL-2003 study.

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The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

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Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial

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Identification of cell surface proteins as potential immunotherapy targets in 12 pediatric cancers

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Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial

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B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

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CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody

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CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

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12 December 2020

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

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Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane.

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12 December 2020

T cell activation by antibody-like immunoreceptors: increase in affinity of the single-chain fragment domain above threshold does not increase T cell activation against antigen-positive target cells but decreases selectivity.

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Chimeric NK-receptor-bearing T cells mediate antitumor immunotherapy.

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12 December 2020

CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells.

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Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells.

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Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells

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The myth of the second remission of acute leukemia in the adult

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

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Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias

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Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia

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Generation of CD19-chimeric antigen receptor modified CD8+ T cells derived from virus-specific central memory T cells

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Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity

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Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

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Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

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IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.

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CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis

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CAReful epitope selection matters

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Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells

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12 December 2020

Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain

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Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia

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High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia

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Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition

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Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival.

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Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

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12 December 2020

Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study

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12 December 2020

Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts.

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12 December 2020

10.1182/ASHEDUCATION-2013.1.348

Identifiers

DOI

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30 August 2017

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